CTX IV (6-12) CAS NO.115722-23-1

CTX IV (6-12) CAS NO.115722-23-1

CTX IV (6-12) CAS NO.115722-23-1

CTX IV (6-12) CAS NO.115722-23-1

CTX IV (6-12) CAS NO.115722-23-1

CTX IV (6-12) is a synthetic peptide fragment corresponding to the C-terminal telopeptide region of type I collagen, specifically cleaved by the enzyme cathepsin K during bone resorption. This high-purity peptide serves as a critical reference standard for researchers studying bone turnover, osteoporosis, and other metabolic bone diseases, offering reliable calibration for ELISA and mass spectrometry assays.


TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
CTX IV (6-12)
CAS NO.
115722-23-1
Appearance
White to off-white lyophilized powder
Molecular Formula
C₄₈H₇₀N₁₀O₇
Molecular Weight
899.14 g/mol
Amino Acid Sequence
Not provided (per request)
Purity (RP-HPLC)
≥98.0%
Solubility
Soluble in 1M acetic acid, DMSO, or deionized water
Endotoxin
< 1 EU/mg
Biological Activity
Specific cleavage site for cathepsin K; widely used as a standard for bone resorption biomarker quantification
Storage Conditions
Store at -20°C, protected from light and moisture
Stock Location
USA / Germany / China (optional, based on actual stock)
MOQ
1 mg


1.Mechanism of Action

CTX IV (6-12) acts as a stable biomarker fragment generated during the enzymatic degradation of collagen by osteoclast-derived cathepsin K. Its presence in biological fluids such as urine or serum reflects active bone resorption rates, making it an essential tool for monitoring therapeutic interventions targeting bone loss and for understanding the pathophysiology of skeletal disorders.

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2.Product Indications

This peptide is primarily indicated for use in academic and pharmaceutical research focused on bone metabolism, including studies on osteoporosis, Paget’s disease, primary hyperparathyroidism, and the efficacy of anti-resorptive therapies. It is suitable for laboratories conducting biomarker validation, assay development, and clinical trial sample analysis where precise measurement of bone breakdown markers is required.

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3.Clinical Efficacy of Product

As a gold-standard reference material, CTX IV (6-12) enables accurate, reproducible quantification of collagen degradation products across multiple platforms. Its consistent purity and defined structure ensure high inter-laboratory comparability, supporting robust clinical research outcomes. Researchers rely on this peptide to correlate bone resorption activity with disease progression, treatment response, and fracture risk assessment in both preclinical and clinical settings.

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4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.


Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.


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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


HotTags:CTXIV, #BoneResorption, #OsteoporosisResearch, #CathepsinK, #CollagenFragment, #BiomarkerStandard, #PeptideSupplier, #MetabolicBoneDisease, #ResearchPeptide, #SerumUrineBiomarker

If you have any product requirements, please send an email to:business@huanqiukeji9.com;whatsapp:85270846510


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