Oligopeptide-50

Oligopeptide-50

Oligopeptide-50

Oligopeptide-50

Oligopeptide-50

Oligopeptide-50 is a synthetically engineered peptide designed for advanced cosmetic and dermatological applications, with a primary focus on promoting hair follicle health and stimulating hair growth. This biomimetic peptide is formulated to target key cellular pathways within the hair follicle, supporting follicular function, extending the growth phase, and mitigating hair loss factors. It is a specialized active ingredient in hair care formulations aimed at improving hair density, thickness, and strength.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Oligopeptide-50
CAS NO.
/
Appearance
White to off-white lyophilized powder
Molecular Formula
C₃₁H₅₁N₉O₁₁S 
Molecular Weight
773.86 g/mol
Purity (RP-HPLC)
≥98.0%
Solubility

Soluble in water (≥10 mg/mL), dilute acetic acid, or DMSO

Endotoxin< 1.0 EU/mg
Biological Activity
Melanogenesis regulator: competitively inhibits α-MSH binding to MC1R, reduces UV-induced melanin production, and supports skin brightening; also exhibits mild anti-inflammatory activity
Storage Conditions
Store at -20°C to -8°C for long-term storage; 4°C for short-term (≤1 week); avoid repeated freeze-thaw cycles; protect from light and moisture
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

Oligopeptide-50 works through a multi-faceted cellular signaling approach to support the hair growth cycle:

  1. Stimulation of Dermal Papilla Cells (DPCs): It directly activates dermal papilla cells, the critical command center of the hair follicle, which regulates growth and cycling. This activation promotes the secretion of growth factors vital for hair follicle health.

  2. Extension of Anagen (Growth) Phase: By modulating signaling pathways such as Wnt/β-catenin, the peptide promotes the prolongation of the anagen phase, delaying the transition to the regression (catagen) and resting (telogen) phases.

  3. Inhibition of Apoptosis: Oligopeptide-50 helps reduce programmed cell death (apoptosis) in follicular keratinocytes, preserving the structural integrity of the hair bulb and supporting sustained hair fiber production.

  4. Potential Anti-Androgenic Modulation: It may help mitigate the negative effects of androgens like DHT on sensitive hair follicles by supporting follicular resilience, making it relevant for androgenetic alopecia.

2.PRODUCT INDICATIONS

This product is indicated for trichological research and the formulation of high-performance hair growth and scalp care products. Key applications include:

  • As a key active ingredient in hair growth serums, scalp lotions, and shampoos for treating pattern hair loss (androgenetic alopecia) in both men and women.

  • In products designed to counteract hair thinning, increase hair density, and improve hair shaft diameter.

  • For scalp treatments aimed at revitalizing hair follicles and improving the overall scalp microenvironment.

  • As part of professional hair regrowth therapies and clinical-grade formulations for hair restoration.

  • In products targeting telogen effluvium (temporary shedding) to help restore normal hair growth cycles.

3.CLINICAL EFFICACY OF PRODUCT

Oligopeptide-50 is supported by in vitro data demonstrating its proliferative and protective effects on hair follicle cells, as well as clinical evaluations on topical formulations. Evidence from studies typically shows:
  • Significant Improvement in Hair Density: Measurable increase in the number of terminal hairs per unit area over a treatment period.

  • Reduction in Daily Hair Shedding: Decreased hair loss, contributing to overall hair retention and volume.

  • Promotion of Thicker Hair Fibers: Improvement in hair shaft diameter, leading to the appearance of fuller, stronger hair.

  • Enhanced Anagen Hair Percentage: Shift in the hair cycle towards a higher proportion of actively growing hairs.

  • Good Tolerability: A favorable safety profile suitable for long-term use on the scalp.

    4.Certificate

    • GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

    Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


    We prioritize:

    1.A rigorous quality management system

    2.Batch traceability and stability data

    3.Professional laboratory testing and validation

    4.Compliance with international trade standards


    Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

    5.DELIVERY & SHIPPING

    We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

    Professional and Secure Packaging

    Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

    We can also customize packaging according to customer needs.

    Shipping Methods 

    Main Method: International Air Freight

    We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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    Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

    We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


    Hot Tags: Pentapeptide-25, Anti-aging peptide, Collagen booster, Skin firming, Wrinkle reducer, Cosmetic ingredient, Peptide synthesis, Skincare, CAS 1000313-64-36, Synthetic peptide, Dermal repair, Extracellular matrix, Fibroblast activation, Topical serum, Cosmetic research, High purity peptide, Supplier, Manufacturer, Bulk order, Cosmetic raw materialResearch peptide, Pharmaceutical


    If you have any product requirements, please send an email to:business@huanqiukeji9.com;whatsapp:852 7084 6510

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