Tetrapeptide-14

Tetrapeptide-14 is a synthetic peptide cosmetic ingredient designed for topical anti-aging formulations, supplied as a high-purity lyophilized powder for incorporation into serums, creams, and lotions. It targets the improvement of skin firmness, elasticity, and the reduction of fine lines by supporting extracellular matrix components, making it suitable for mature and photoaged skin seeking a more lifted and resilient appearance.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Tetrapeptide-14
CAS NO.	/
Appearance	White to off-white lyophilized powder
Molecular Formula	C₂₀H₂₈N₄O₆
Molecular Weight	~ 420.5 Da g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in water, phosphate‑buffered saline (PBS), or dilute aqueous solutions. Recommended to dissolve in sterile water to prepare a 0.1–1.0 mg/mL stock solution.
Endotoxin	< 1.0 EU/mg
Biological Activity	Tetrapeptide‑14 is a synthetic peptide used in cosmetic formulations for its reported ability to support collagen synthesis, improve skin elasticity, and reduce the appearance of fine lines. It is often included in anti‑aging and firming skincare products.
Storage Conditions	Lyophilized powder: Store desiccated at –20 °C or below, protected from light, for long‑term stability. Reconstituted solution: Aliquot and store at ≤ –20 °C; avoid repeated freeze‑thaw cycles.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

Tetrapeptide-14 penetrates the epidermis and acts on dermal fibroblasts to stimulate the synthesis of key structural proteins such as collagen and elastin, enhancing the density and organization of the extracellular matrix. It also modulates signaling pathways involved in matrix degradation, helping to reduce the breakdown of existing collagen and elastin fibers, thereby improving skin firmness and reducing the appearance of wrinkles over time.

2.PRODUCT INDICATIONS

This peptide is indicated for research and development of topical cosmetic formulations aimed at improving skin firmness, elasticity, and reducing signs of aging in mature, photoaged, and sagging skin. It is used in products such as anti-aging serums, firming creams, and eye contour treatments, as well as in in vitro and ex vivo models to evaluate collagen synthesis, skin elasticity, and wrinkle reduction in aged skin conditions.

3.CLINICAL EFFICACY OF PRODUCT

Clinical evaluations of formulations containing Tetrapeptide-14 demonstrate significant improvements in skin firmness, elasticity, and reduction in the appearance of fine lines and wrinkles after 8 to 12 weeks of topical application, with instrumental measurements showing increased skin density and subjective improvements in skin lifting and smoothness. While these results are supportive, data are primarily from manufacturer-sponsored studies and small-scale trials, positioning Tetrapeptide-14 as a cosmetic ingredient with evidence for firming and anti-wrinkle benefits in anti-aging formulations.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.