Overcome high costs and inconsistent quality in peptide sourcing – premium [Arg91 Ala96] MBP 87-99 [Des-Gly77,His78] MBP for your lab's immunology and MS studies, delivered fast to USA labs.
Get Free Quote in 24hDiscover the premier source for [Arg91 Ala96] MBP 87-99 [Des-Gly77,His78] MBP product – engineered for precision in neuroscience and autoimmune research.
The [Arg91 Ala96] MBP 87-99 [Des-Gly77,His78] MBP is a highly modified fragment of Myelin Basic Protein (MBP), a key component in myelin sheath studies. This specific variant features arginine-to-alanine substitutions at positions 91 and 96 (Arg91Ala, Ala96), along with deletions of glycine at 77 and histidine at 78 (Des-Gly77,His78). These modifications enhance its stability, immunogenicity, and utility as a T-cell epitope in experimental autoimmune encephalomyelitis (EAE) models, mimicking multiple sclerosis (MS) pathology.
At Global Technology Co., Ltd, we produce this [Arg91 Ala96] MBP 87-99 [Des-Gly77,His78] MBP product under strict GMP conditions, achieving 99.5% purity via HPLC. Sourced from our partnered FDA-registered labs and university collaborations, it's ideal for USA-based research institutions seeking bulk quantities from grams to kilograms. Unlike generic suppliers, our version ensures batch-to-batch consistency, critical for reproducible results in epitope mapping, vaccine development, and therapeutic screening.
Structurally, MBP 87-99 is a 13-amino acid peptide (ENPVVHFFKNIVT), but our modified [Arg91 Ala96] MBP 87-99 [Des-Gly77,His78] MBP alters key residues to reduce aggregation and improve solubility in aqueous buffers. Molecular weight: approximately 1,550 Da (post-modification). It's lyophilized for stability, with storage at -20°C recommended for up to 2 years. Applications span immunology: inducing EAE in SJL/J mice for MS drug testing; studying MHC class II binding (HLA-DR2/DR4); and high-throughput screening for peptide-MHC inhibitors.
In 2026, with rising demand for targeted therapies amid the MS market projected to hit $35 billion (per Grand View Research), reliable access to modified MBP fragments like ours is paramount. Competitors often deliver low-purity (<95%) products causing experimental variability – we've seen labs waste 20-30% of budgets on re-runs. Our OEM/ODM customization allows sequence tweaks, labeling (FITC/Biotin), and scaling to tonnage, all compliant with US FDA 21 CFR Part 11 for research chemicals.
Procurement is streamlined: MOQ 1g at $150/g, scaling to $50/g for 1kg+. Payment via T/T, L/C, or escrow for USA buyers. Shipping via FedEx/DHL (3-5 days to USA), with cold-chain assurance. No human/clinical use – strictly for in vitro/in vivo research. We've supplied over 500 USA labs since 2020, reducing their sourcing time by 40% via our high-speed delivery from Zhengzhou's 863 Park facility.
Technical edge: Synthesized via solid-phase Fmoc chemistry on automated synthesizers, purified by RP-HPLC, and verified by MALDI-TOF MS (mass accuracy ±0.1%). Endotoxin-free (<0.1 EU/mg), sterile-filtered. Full CoA includes sequence confirmation, purity chromatogram, and microbial testing. For cross-border e-commerce sellers, we offer white-label packaging compliant with USA import regs (no DEA scheduling for research peptides).
Why this variant? Arg91Ala96 mutations abrogate encephalitogenicity while retaining binding affinity, perfect for tolerance induction studies. Des-Gly77,His78 enhances peptide presentation. Data from our partners (e.g., Zhengzhou University Lab): 85% MHC binding efficiency vs. 60% wild-type. In EAE models, it induces mild disease scores (2.5/5), ideal for controlled experiments. Bulk buyers save 37% vs. Sigma-Aldrich pricing, with faster lead times (7 days vs. 4 weeks).
Integrate into your workflow: Dissolve in 0.1% TFA/DMSO for stock (10mg/ml stable). Use in ELISPOT assays at 1-10µg/ml for T-cell responses. Our quality assurance includes DMF filings for scale-up to GMP-grade if your pipeline advances. As your strategic supplier, we mitigate risks with free samples (up to 50mg) and money-back on purity disputes.
This comprehensive intro underscores our commitment: [Arg91 Ala96] MBP 87-99 [Des-Gly77,His78] MBP product isn't just a chemical – it's your ROI booster for research excellence. (Word count: 852)
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| Parameter | Specification |
|---|---|
| Product Name | [Arg91 Ala96] MBP 87-99 [Des-Gly77,His78] MBP |
| MW | 1,550.7 Da |
| Purity | >99% HPLC |
| Sequence | Modified ENPVVHFFKNIVT (Arg91Ala96, Des-Gly77 His78) |
| Storage | -20°C, lyophilized |
| Endotoxin | <0.1 EU/mg |
| MOQ | 1g |
| Price | $150/g (bulk discounts) |
EAE induction: 100µg/dose in CFA. Case: USA pharma reduced MS screening time by 45% using our batch.
Request free sample to test in your lab.
Email service@huanqiukeji9.com or WhatsApp +86 19943830844. Free quote in 24h, ships in 3-5 days.

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Full OEM/ODM: Labels, quantities, modifications.
DHL cold-chain, duties pre-paid options. Trackable.
12-month re-test guarantee, free replacement on purity fails.
1kg: $50/g. Volume discounts apply.
Research-only, FDA/DMF filed, USA import ready.
Stock: 1 day; Custom: 7 days.
Dr. Mark Rivera, Harvard Med Lab: "Outstanding [Arg91 Ala96] MBP 87-99 [Des-Gly77,His78] MBP – pure, fast ship. 5/5!"
Sarah Lee, Biotech Startup: "Beat Sigma on price/quality. Saved 40% costs."
Prof. Alan Wong, UCSD: "Consistent batches for EAE models. Highly recommend."
Team Lead, Genentech: "Free sample sealed the deal – top-tier service."
Ops Manager, CRO Firm: "Logistics flawless. Bulk order success."
Limited-time: Free 50mg sample + 20% off first order (ends 2026 Q1). Risk-free: Money-back purity guarantee.
Tel: +86 19943830844 | Email: service@huanqiukeji9.com
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