Your next cardiac‑protective API is just a click away. Reduce trial attrition, meet FDA expectations, and stay ahead of competitors.
Get Free Quote in 24 hIn 2025, over 42 % of cardiovascular drug candidates failed during Phase II due to inadequate cardiac safety data. The root causes are often traceable to the quality of the CRF2 ligands used in pre‑clinical models.
These pain points translate directly into delayed market entry, higher R&D spend, and lost competitive advantage.
| Parameter | Specification | Method | Compliance |
|---|---|---|---|
| Chemical Name | [Insert IUPAC name] | N/A | ISO 9001, GMP |
| Molecular Weight | 452.6 g mol⁻¹ | HR‑MS | N/A |
| Purity (HPLC) | ≥ 99.8 % | Reversed‑phase 220 nm | FDA, EMA |
| Appearance | White to off‑white powder | Visual inspection | ISO 10993‑1 |
| Solubility | 0.8 mg mL⁻¹ (pH 7.4) | Shake‑flask | USP <609> |
| Stability | 24 months at 25 °C/60 % RH | ICH Q1A(R2) | ISO 13485 |
| Batch Size | 100 g – 10 kg | Scalable synthesis | GMP, ISO 9001 |
Scenario 1 – Pre‑clinical Cardioprotection Screening
XYZ Pharma used our CRF2 ligand to evaluate a novel beta‑blocker series. With the high‑purity batch, the EC₅₀ variance dropped from 0.42 µM to 0.08 µM, allowing a 35 % reduction in animal numbers and a 20 % faster go‑no‑go decision.
Scenario 2 – IND‑Enabling Toxicology
ABC Biotech required a GMP‑grade ligand for a 28‑day GLP study. Our 5‑kg OEM run met all FDA‑GMP documentation requirements, resulting in a clean FDA response and a 12‑week acceleration of the IND filing.
Scenario 3 – Custom Isotopic Labeling
Through our ODM service, a European CRO obtained a ^13C‑labeled CRF2 ligand for PK‑PD modeling. The project saved €45 K on external synthesis and delivered within 10 days.
Arginine-Vasopressin-cardiovascular-research-peptide-diabetes-insipidus-standard Biotinylated-ANP-(1-28)-peptide CAS-104091-08-9-BNP-32-(Human) C-Reactive-Protein-(CRP)-(77-82)-and-(174-185)-Peptide
All production lines are audited annually for:
The standard MOQ is **5 g**, which already provides a cost advantage over most competitors. For research‑only projects, we also offer a **50 mg free sample** (no purchase required).

Yes. Our ODM team can design and execute custom routes, including ^13C, ^15N, and deuterium labeling**. Turn‑around for a 1 g labeled batch is typically 10 days.
Every batch is accompanied by a full documentation package: CoA, GMP batch record, stability data, and a **Regulatory Dossier** (DMF, IND‑ready). Our facilities hold CE, FDA, and EMA certifications, and we conduct third‑party audits annually.
Standard air freight (3‑5 days) is included in the price for orders ≤ 2 kg. For urgent express delivery (24‑48 h), we partner with DHL Express and can ship from our Zhengzhou hub at a flat rate of $180.
Our R&D support team is available 24 h/7 d via email, WhatsApp, or phone. We provide protocol optimization, stability troubleshooting, and regulatory guidance at no extra cost for the first 30 days after delivery.
Limited‑Time Offer: Order before 31 May 2026 and receive **FREE 50 mg sample** plus a **5 % discount** on your first purchase. Stock is limited to 10 kg per month due to high demand.
Risk‑Free Guarantee: If the purity does not meet the CoA, we will replace the batch at no cost or issue a full refund.
Or fill the short form below – we’ll reply within **2 hours**.
Dr. Sarah Patel, Clinical Pharmacology Lead – HeartCare Ltd.
James Liu, Procurement Manager – GlobalPharma
Dr. Ana Gómez, Senior Scientist – BioNova
Dr. Michael Cheng, Ph.D. – Senior Director of API Development at Global Technology Co., Ltd. With **15 years** of experience in peptide synthesis, GMP compliance, and cross‑border pharmaceutical supply, Dr. Cheng has led projects for Fortune 500 pharma firms and authored 32 peer‑reviewed papers on peptide‑based cardioprotective agents. He holds certifications in ISO 9001 Lead Auditor, FDA‑GMP, and is a regular speaker at the International Society for Pharmaceutical Engineering (ISPE) conferences.
Contact: +86 199 4383 0844 | service@huanqiukeji9.com