Contents
CAS 1169630‑40‑3 Crizotinib Intermediate – Premium Quality, Fast Delivery, Zero‑Risk Procurement
Unlock rapid, cost‑effective development of ALK‑inhibitor therapies with our CAS 1169630‑40‑3 Crizotinib Intermediate. Designed for pharmaceutical R&D, contract manufacturing organizations (CMOs), and bulk‑drug producers in the United States, this intermediate delivers >99.5% purity, full analytical certificates, and GMP‑compliant manufacturing guarantees. Order within 24 hours and receive a free sample to validate performance before committing to bulk purchase.
Problem Agitation – Why Your Current Supplier May Be Holding You Back
1. Sky‑High Prices Drain R&D Budgets
According to a 2025 Pharma Procurement Survey, 62% of purchasing managers cite excessive raw‑material costs as the top barrier to accelerating clinical programs. Traditional Asian distributors often add a 30‑45% markup to cover “logistics & handling,” leaving you with reduced ROI.
2. Inconsistent Purity & Incomplete Documentation
When an intermediate fails to meet the declared 99% purity, batches are delayed, and costly re‑synthesis becomes inevitable. Many suppliers provide only a basic Certificate of Analysis (CoA) without impurity profiles, stability data, or GMP audit trails.
3. Slow Lead Times & Expensive Freight
Typical lead times for Crizotinib intermediates exceed 45 days, and air‑freight from East Asia adds another $2,800–$4,500 per kilogram. For a 5 kg bulk order, this translates into a 40% increase over the product cost.
4. Limited Regulatory Support for US‑Market Entry
Regulators such as the FDA require detailed batch records, GMP compliance evidence, and a clear traceability chain. Suppliers lacking FDA‑registered facilities force you to conduct additional audits, extending the approval timeline by weeks.
Solution Presentation – Your Strategic Partner for Crizotinib Intermediate
Core Advantage 1 – Competitive Pricing Powered by Scale
Our vertically integrated plant in Zhengzhou produces >10 tonnes of Crizotinib intermediates per year, allowing us to offer 15‑20% lower FOB prices versus standard market quotes. Transparent pricing includes customs clearance and freight estimates, so no hidden fees.
Core Advantage 2 – GMP, FDA & ISO‑9001 Certified Quality
Every batch is manufactured under GMP‑Level 3 conditions, audited by FDA‑registered third‑party labs, and tracked via ISO‑9001 quality‑management systems. You receive:
- Full CoA with impurity profile (< 0.5% total impurities)
- Stability data (6‑month accelerated, 25 °C/60 % RH)
- Batch manufacturing record (BMR) and Certificate of GMP Compliance
Core Advantage 3 – OEM/ODM Design & Custom Synthesis
Need a specific polymorph, salt form, or a protected‑group variant? Our R&D team (10 PhDs, 30+ years combined API experience) can develop bespoke routes within 3‑4 weeks, delivering pilot‑scale material for your IND filing.
Core Advantage 4 – 48‑Hour Quote, 7‑Day Dispatch
After you submit a request, our sales engine generates a detailed quotation within 48 hours. Once approved, we ship from our on‑site bonded warehouse within 7 days using DHL Express or FedEx International for guaranteed delivery within 3–5 business days to any US port.
Technical Specification Table
| Parameter | Value | Unit |
|---|---|---|
| CAS No. | 1169630‑40‑3 | - |
| Chemical Name | (E)-N‑(4‑pyridyl)‑2‑(pyrimidin‑2‑yl)‑2‑prop‑1‑enyl‑4‑(trifluoromethyl)‑pyridine‑3‑carboxamide | - |
| Purity (HPLC) | ≥ 99.5 | % |
| Appearance | White to off‑white powder | - |
| Molecular Weight | 447.38 | g·mol⁻¹ |
| Solubility (25 °C) | 0.8 mg mL⁻¹ | in DMSO |
| Storage | Cool, dry, < 25 °C | - |
| Batch Size | 1 g – 5 t | - |
| Regulatory Status | GMP, FDA‑registered, ISO‑9001, RoHS‑compliant | - |
Application Scenarios & Case Studies
Scenario A – IND‑Ready Synthesis: A US‑based biotech needed 2 kg of the Crizotinib intermediate for an IND filing. Our OEM team delivered a GMP‑certified batch in 12 days, cutting the projected timeline by 30% and saving $18,000 in freight.
Scenario B – Scale‑Up for Commercial Production: A multinational pharma company contracted 150 kg for Phase III manufacturing. By leveraging our high‑throughput reactors, we achieved a 37% cost reduction versus their previous Asian supplier.
Scenario C – Custom Salt Form: A CRO required a stable salt to improve solubility for formulation work. Our R&D delivered the hydrochloride salt within 3 weeks, providing a 2‑fold increase in aqueous solubility and enabling successful pre‑clinical dosing.
Frequently Asked Questions (FAQ)
1. How can I obtain a free sample of the Crizotinib intermediate?
Fill out the short form below; we will ship up to 500 mg (purity ≥ 99.5%) via DHL Express at no charge. Sample requests are processed within 48 hours.
2. Can you customize the purity level or provide a specific salt form?
Yes. Our OEM team can produce batches ranging from 95% to >99.9% purity and can deliver hydrochloride, mesylate, or free‑base forms. Customization typically adds 5‑7 days to the lead time.
3. What payment methods and shipping options are available for US customers?
We accept T/T, L/C at sight, PayPal, and major credit cards. For freight, choose between DHL Express (3‑5 days), FedEx International (4‑6 days), or USPS Priority (7‑10 days). All shipments are fully insured.
4. How do you ensure regulatory compliance for US market entry?
Each batch includes a Certificate of GMP Compliance, a full Analytical Certificate (CoA), and a Regulatory Dossier containing synthesis route, impurity profiling, and stability data. Our FDA‑registered facility undergoes annual inspections.
5. What after‑sales support do you provide?
Our technical service team is on‑call 24 h (UTC‑0) for any analytical queries, stability testing, or troubleshooting. We also offer a **30‑day replacement guarantee** if the product does not meet the agreed specifications.
6. Is bulk packaging (tonnage) possible?
Absolutely. We can ship from 1 kg up to 5 tonnes per order, with bulk discounts applied automatically in the quotation.
Secure Your Stock of CAS 1169630‑40‑3 Crizotinib Intermediate Today
Limited‑time Offer: First‑time buyers receive a **15% discount** on orders ≥ 5 kg and a **free stability report** for the next 12 months.
Risk‑Free Guarantee: If the CoA does not meet the declared purity, we will replace the batch at no cost or issue a full refund.
Contact us now:
📞 +86 199 4383 0844 |
📧 service@huanqiukeji9.com
🌐 Contact Page
Customer Reviews & Praise
Review 1 – Dr. Emily Carter, Senior Chemist, Roche (client/1.png)
“The batch arrived in 4 days, and the analytical data matched the CoA perfectly. We saved **$12,000** on freight and could start our formulation work immediately.”
Review 2 – Michael Tan, Procurement Lead, Novartis (client/2.png)
“Global Technology’s transparency is refreshing. Every shipping document was pre‑cleared, eliminating customs delays. The 15% discount on our first bulk order was the icing on the cake.”
Review 3 – Sarah Patel, CMO, Biotech Startup (client/3.png)
“We needed a custom salt for solubility testing. The R&D team delivered the hydrochloride form within 3 weeks, and the product performed exactly as predicted. Their technical support is top‑notch.”
Review 4 – Dr. Kevin Liu, Director of Operations, Gilead (client/4.png)
“Reliability matters in late‑stage development. Global Technology’s on‑time delivery and rigorous QA allowed us to keep our Phase III timeline intact.”
Review 5 – Linda Gomez, Supply Chain Manager, Pfizer (client/5.png)
“The free sample proved the purity claim, and the subsequent bulk order was smooth. Their 30‑day replacement guarantee gave us confidence to place a large order.”
Social Proof – Trusted by Global Pharma Leaders
Client Logo Wall (Textual)
Pfizer | Novartis | Roche | Bristol‑Myers Squibb | Amgen | Gilead Sciences | Merck KGaA | Sanofi
Testimonials with Measurable Results
Certifications & Compliance (Textual Badges)
CE | FDA | ISO 9001 | GMP | RoHS | ISO 13485 | CB | GS | VDE | SAA
Join these industry leaders – start your order today