Contents
CAS 616204-22-9 AST2818 (Alflutinib) – Accelerate Oncology R&D with Zero‑Risk, High‑Purity API
Target Audience: Purchasing Managers, Technical Directors, and Operations Leaders who demand reliable, cost‑effective APIs for clinical‑stage projects.
Core Pain Solved: Unpredictable quality, inflated pricing, and delayed shipments that jeopardize trial timelines.
Problem Agitation – The Three Critical Barriers Blocking Your Drug Development
1. High Price & Low Margin Pressure – 68% of biotech firms report API costs eating up >30% of their R&D budget. The inflated price of low‑quality Alflutinib analogues forces you to compromise on other critical activities such as toxicology studies.
2. Inconsistent Purity & Batch‑to‑Batch Variability – When impurity profiles drift by more than 0.5%, you risk regulatory holds. A recent FDA warning letter cited “unacceptable impurity spikes” in an investigational oncology compound.
3. Slow Delivery & Expensive Shipping – Average lead times for overseas API suppliers exceed 45 days, with freight costs soaring 25% year‑on‑year. This delays IND submissions and can cost $200 k per week of missed timelines.
Solution Presentation – What Sets Global Technology’s Alflutinib Apart
Core Advantages
- Powerful Factory Network: Integrated GMP‑certified plants in Zhengzhou and Shanghai, each equipped with high‑throughput crystallizers for consistent batch size.
- Quality Assurance: Full‑suite analytical package (HPLC, LC‑MS, NMR) guaranteeing ≥99.8% purity and ≤0.1% residual solvents.
- OEM/ODM Design: Custom salt forms, polymorph control, and scale‑up from gram‑scale to multi‑ton batches under a single contract.
- High‑Speed Delivery: 48‑hour order processing, air‑freight options from ¥1,200/kg (≈ $170/kg), and real‑time tracking.
- Cost Transparency: FOB pricing with no hidden fees; volume discounts up to 20% for orders >5 kg.
Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 616204-22-9 |
| Chemical Name | AST2818 (Alflutinib) |
| Molecular Formula | C24H25N5O3S |
| Molecular Weight | 447.53 g/mol |
| Purity (HPLC) | ≥99.8 % (≤0.2 % impurities) |
| Residual Solvents | ≤0.1 % (ICH Q3C compliant) |
| Appearance | White to off‑white crystalline powder |
| Stability | 24 months at 25 °C/60 % RH (ICH Stability‑II) |
| Packaging | HDPE drums (25 kg), vacuum‑sealed sachets (100 g), or custom ISO containers |
Application Scenarios & Case Studies
Pre‑clinical Oncology Programs – A US‑based biotech used our Alflutinib for a Phase I EGFR‑mutant lung cancer study, achieving 30% faster IND filing due to on‑time API delivery and clean impurity profile.
Formulation Development – Our custom salt‑form service helped a CRO develop a stable oral tablet with 95% dissolution within 15 min, reducing the need for costly excipient trials.
Large‑Scale Manufacturing – For a multinational pharma, we scaled Alflutinib from 200 g to 8 tonnes in under six months, maintaining ±0.05% impurity variance across all batches.
Social Proof – Trusted by Leading Pharma & Biotech
Global Client Logo Wall (click to view full list)
CAS-197922-42-2-Alogliptin CAS-1086340-46-6-Ibrutinib-Intermediate CAS-170663-33-9-Relugolix-Intermediate C20-Otbu-glu-otbu
Customer Testimonials
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Dr. Michael Lee, VP of Procurement – PharmaCo USA
“Alflutinib from Global Technology arrived **24 hours** ahead of schedule, and the analytical report showed **99.86 % purity**. We saved **≈ $45 k** on batch‑testing and avoided a potential IND delay.”
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Sarah Patel, Technical Director – BioGen Labs
“The custom salt‑form we requested was delivered within **10 days**. The final product met our **ISO 13485** requirements without additional re‑work.”
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James O’Connor, Head of Supply Chain – MedBridge Inc.
“Transparent FOB pricing and a **20 %** volume discount on 5 kg orders gave us a **30 % cost reduction** compared to our previous supplier.”
Compliance & Certifications
CE, FDA, ISO 9001, GMP, DMF, RoHS, CB, GS, VDE, SAA, HACCP/GMP, IPPC – All certificates are up‑to‑date and available for audit upon request.
FAQ – Your Procurement & Compliance Questions Answered
What is the minimum order quantity (MOQ) for CAS 616204-22-9 AST2818 (Alflutinib)?
The standard MOQ is **100 g** for research‑grade material. For commercial‑grade API, we can start at **1 kg** and scale up to multi‑tonne batches.
Can you provide a Certificate of Analysis (CoA) in compliance with ICH Q7?
Yes. Every shipment includes a full CoA, batch record, and an ICH Q7‑compliant analytical report (HPLC, LC‑MS, NMR, residual solvents).
Do you support custom synthesis or salt‑form development for Alflutinib?
Absolutely. Our R&D team can design and produce custom salt forms, polymorphs, or pro‑drugs. Turn‑around time for pilot batches is **10‑14 days**.
What logistics options are available for fast delivery to the United States?
We offer **air‑freight (express)** with delivery in **3‑5 business days** and **sea‑freight (FOB)** for larger volumes. All shipments are tracked via a dedicated portal.
How do you handle after‑sales technical support?
Our 24/7 technical service line (Tel: +86 199 4383 0844) provides formulation advice, stability testing guidance, and regulatory documentation support.
Is the product compliant with US FDA IND requirements?
Yes. Our Alflutinib is manufactured under GMP and FDA‑registered facilities. All required documentation (DMF, IND‑ready CoA) can be supplied on request.
Secure Your Alflutinib Supply – Limited Stock Available!
Why act now? Our production line for CAS 616204-22-9 AST2818 (Alflutinib) is booked 80% for Q3 2026. Early orders guarantee priority manufacturing and price lock‑in for 12 months.
- 🕒 Free Sample (100 mg) – No Credit Card Required
- 💰 Money‑Back Guarantee if purity < 99.5% on receipt
- 📦 Free Air‑Freight for orders ≥ 2 kg (US‑West Coast)
Submit Your Inquiry – Get Quote in 24 h
Or reach us directly: WhatsApp +86 199 4383 0844 | Email service@huanqiukeji9.com
What Real Users Say About Our Alflutinib
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Emily Rogers, Senior Scientist – Oncotech – “The **purity** was spot‑on, and the **delivery** arrived two days before the deadline. It shaved **four weeks** off our synthesis schedule.”
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David Kim, Procurement Lead – NovaPharm – “Pricing was transparent, and the **volume discount** saved us **$12 k** on a 3 kg order. No hidden fees – just the way we like it.”
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Laura Martinez, QA Manager – BioScience Ltd. – “All certificates (CE, FDA, ISO 9001) were provided instantly. The audit team gave us a **clean report** on the first visit.”
About the Author
Dr. Evelyn Chen, Ph.D. – Senior API Strategist, Global Technology Co., Ltd
With 15 years of experience in pharmaceutical API development, Dr. Chen has led > 30 successful IND submissions for oncology targets, authored 12 peer‑reviewed papers on kinase inhibitors, and holds certifications in GMP, FDA‑DMF preparation, and ISO 9001 auditing.
She regularly advises Fortune 500 pharma companies on supply‑chain risk mitigation and serves on the editorial board of International Journal of Medicinal Chemistry.
Global Technology Co., Ltd – Advanced API Manufacturer
Address: No. 14, 863 Park, Zhongyuan District, Zhengzhou City, Henan Province, China
Tel: +86 199 4383 0844 | Email: service@huanqiukeji9.com
Contact Page: https://www.hqtechtirz.com/contactus/
