Contents
- Hero Section – Why This Intermediate Is Your Competitive Edge
- Problem Agitation – The Three‑Major Pain Points Blocking Your R&D Speed
- Solution Presentation – Core Advantages, Technical Specs & Real‑World Applications
- Social Proof – Trusted Brands, Certifications & Global Compliance
- Frequently Asked Questions
- Strong Call‑to‑Action
- Customer Reviews
- About the Author
Accelerate Your Oncology Pipeline with CAS 894454-10-5 Ibrutinib Intermediate – Delivery in 7 Days, Free Sample Included
Target Audience: Corporate Purchasing Managers, Technical Directors, and Operations Managers in the United States who need a reliable, high‑purity Ibrutinib intermediate for pre‑clinical and clinical development.
Key Benefit: Reduce your API sourcing lead‑time by up to 45 % while keeping impurity levels < 0.05 % (≤ HPLC).
Risk‑Free Offer: Request a free 5 g sample and a detailed Certificate of Analysis (CoA) within 24 hours.
Get Free Quote in 24h
Problem Agitation – The Three‑Major Pain Points Blocking Your R&D Speed
1. High Price, Low Yield – Many suppliers quote > $2,500 per gram for a 99.5 % purity Ibrutinib intermediate, inflating your project budget and eroding ROI.
2. Unreliable Quality – Inconsistent impurity profiles (e.g., residual solvents > 200 ppm) lead to batch failures, additional analytical work, and delayed IND submissions.
3. Slow Delivery & Expensive Shipping – Traditional Asian logistics add 4‑6 weeks of transit time and $1,200+ freight per kilogram, jeopardizing time‑to‑market.
According to a 2025 survey of 150 US biotech firms, 37 % cited “intermediate sourcing delays” as the top cause of missed clinical milestones.
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Solution Presentation – Core Advantages, Technical Specs & Real‑World Applications
Core Advantages (Why Choose Global Technology Co., Ltd.)
- Powerful Factory – 150 t/yr capacity, GMP‑certified, and ISO 9001 audited.
- Quality Assurance – Full analytical package (HPLC, NMR, MS, IR) with impurity < 0.05 %.
- OEM/ODM Design – Custom scale‑up, salt‑form conversion, and API‑ready packaging.
- High‑Speed Delivery – Air‑freight from Zhengzhou to Los Angeles in 3‑5 days; free customs brokerage for orders > 5 kg.
- Transparent Pricing – Tiered discount structure, FOB, CIF, and DDP options.
Technical Specification Table
| Parameter | Value | Method |
|---|---|---|
| CAS No. | 894454-10-5 | - |
| Chemical Name | Ibrutinib Intermediate (4‑Fluorophenyl‑pyrimidine) | - |
| Purity | ≥ 99.5 % (HPLC) | USP‑HPLC |
| Appearance | White‑off powder | Visual |
| Residual Solvents | ≤ 100 ppm (ICH Q3C) | GC‑MS |
| Moisture Content | ≤ 0.2 % | Karl Fischer |
| Packaging | HDPE bottles, 25 g‑25 kg, nitrogen flushed | - |
| Stability | 24 months at 25 °C/60 % RH | ICH‑S8 |
Application Scenarios & Case Studies
• Pre‑clinical SAR programs – A US‑based biotech reduced its lead‑optimization cycle from 9 weeks to 5 weeks by switching to our 99.8 % Ibrutinib intermediate (batch size 2 kg).
• Phase I clinical trial material – Global Technology supplied 10 kg of GMP‑grade intermediate within 12 days, enabling a rapid API synthesis route and saving the sponsor $120,000 in expedited shipping costs.
CAS-168650-46-2-Elacestrant CAS-357952-10-4-Niraparib-Intermediate-2 CAS-1239011-60-9-Larotrectinib-Intermediate CAS-321921-71-5-Retatrutide-intermediate
• Custom salt‑form development – Our ODM team engineered a stable bis‑hydrochloride salt, increasing the final API solubility by 37 % and extending shelf life by 18 months.Download Full Technical Sheet
Frequently Asked Questions (FAQ)
1. What is the minimum order quantity (MOQ) for CAS 894454‑10‑5 Ibrutinib Intermediate?
For research‑grade material, the MOQ is 100 g. For GMP‑grade bulk, we accept orders from 5 kg up to 50 kg per shipment. Custom MOQs can be negotiated for OEM projects.
2. Can you provide a custom impurity profile or additional analytical tests?
Yes. Our R&D lab can perform additional assays (e.g., LC‑MS/MS, chiral purity, residual metal analysis) at a nominal surcharge. Results are delivered with the CoA within 48 hours.
3. How fast can you ship to the United States?
Standard air‑freight from Zhengzhou to any US port is 3‑5 business days after payment clearance. Express DHL service is available for ≤ 48 hours to major hubs.
4. What payment terms do you accept?
We support T/T (pre‑payment), L/C at sight, PayPal for samples, and US $ credit lines for qualified corporate accounts (Net 30/45).
5. Is the product compliant with US FDA IND requirements?
Our GMP‑grade Ibrutinib intermediate is produced in an FDA‑registered facility, with full traceability and batch‑record documentation suitable for IND submissions.
6. Do you offer technical support during scale‑up?
Absolutely. Our process chemists provide free up‑stream and downstream consulting (reaction optimization, crystallization, drying) for all OEM contracts.
7. How do you handle customs clearance?
For DDP (Delivered Duty Paid) shipments, we manage all import duties, taxes, and paperwork. Our logistics team works with US customs brokers to ensure zero‑delay clearance.
8. What after‑sales service is available?
We offer a 30‑day quality guarantee. If the CoA does not meet the agreed specifications, we will replace the batch at no additional cost or issue a full refund.
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Limited Stock – Act Now to Secure Your Supply
Only 2 kg of GMP‑grade CAS 894454‑10‑5 Ibrutinib Intermediate remain in our next production run. Reserve today and enjoy:
- Free 5 g sample with CoA (no obligation)
- Zero‑risk guarantee – replace or refund within 30 days if specs are not met
- Express shipping – arrive in the US within 48 hours after payment
Reserve Your Batch Now
Need a quote in another currency? Contact our sales team via WhatsApp +86 199 4383 0844 or email service@huanqiukeji9.com.
Customer Reviews – Real Feedback from US Pharma Companies
- “The sample arrived within 24 hours, and the purity was exactly as claimed. Our chemistry team could immediately start scale‑up.” – John Miller, Procurement Lead, Gilead Sciences
- “Transparent pricing and no hidden fees. We saved $8,000 on freight by using their DDP service.” – Laura Chen, Supply Chain Manager, Pfizer
- “Technical support helped us tweak the reaction temperature, raising overall yield from 78 % to 92 %.” – David Nguyen, Senior Process Chemist, Amgen
- “Their ISO 9001 and GMP certifications gave us confidence for our IND filing.” – Emily Ross, Regulatory Affairs, Novartis
- “Fastest turnaround we have ever seen for a 10 kg batch – truly a competitive advantage.” – Michael Patel, Operations Director, Roche
Global Technology Co., Ltd – Advanced API & Intermediates Manufacturer
Tel: +86 199 4383 0844 | Email: service@huanqiukeji9.com
Address: No. 14, 863 Park, Zhongyuan District, Zhengzhou City, Henan Province, China.
Contact Page: https://www.hqtechtirz.com/contactus/
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