CAS 928006-46-2 ADC Linker – High‑Purity, Fast‑Delivery Solution for Antibody‑Drug Conjugates
Designed for R&D managers, technical directors, and operations leaders who need reliable, cost‑effective ADC linkers without compromising on quality.
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The Real‑World Challenges of ADC Production
1. Sky‑rocketing linker costs – Many suppliers quote > $1,200 per gram for high‑purity ADC linkers, inflating project budgets by 30‑40%.
2. Inconsistent purity & batch‑to‑batch variation – Even a 0.5 % impurity can jeopardize conjugation efficiency, leading to failed clinical batches.
3. Lengthy lead times – Traditional manufacturers in Europe or the US often need 6‑8 weeks for small‑scale synthesis, slowing down R&D cycles.
4. Complex regulatory paperwork – Missing GMP, ISO, or CE documentation forces re‑qualification and adds weeks of delay.
5. High shipping fees & customs hurdles – Air freight from overseas can exceed $200 per kg, and unpredictable customs clearance adds risk.
If any of these pain points appear in your procurement checklist, you are likely losing time, money, and competitive advantage.
See How We Solve Them →Why Our CAS 928006‑46‑2 ADC Linker Is the Competitive Edge
- Cost‑Effective Pricing – $845 / g (≈30 % lower than average market price) without compromising purity.
- Verified High Purity – ≥ 99.5 % HPLC purity, ≤ 0.1 % residual metals, certified by independent third‑party labs.
- Rapid Turn‑Around – Standard 2‑week delivery** for 10 g orders from our Zhengzhou GMP‑certified facility.
- Full Regulatory Package – CE, FDA, ISO 9001, GMP, RoHS, and CB certificates included in every shipment.
- OEM/ODM Design Support – Custom functional groups, linker length, and cleavable motifs available on request.
- Transparent Logistics – DDP (Delivered Duty Paid) to any US port, customs brokerage included, average freight < $120 / kg.
Result: 30‑45 % reduction in total ADC project cost and 50 % faster time‑to‑clinical.
View Technical Specs →Technical Specification Sheet
| Parameter | Value | Unit |
|---|---|---|
| CAS Number | 928006‑46‑2 | ‑ |
| Molecular Formula | C34H48N8O9S | ‑ |
| Molecular Weight | 732.86 | g mol⁻¹ |
| Purity (HPLC) | ≥ 99.5 % | ‑ |
| Appearance | White to off‑white powder | ‑ |
| Solubility | DMSO 50 mg mL⁻¹; DMF 30 mg mL⁻¹ | ‑ |
| Stability | -20 °C to 25 °C, protected from moisture | ‑ |
| Packaging | Vacuum‑sealed HDPE bottle, 10 g, 25 g, 100 g | ‑ |
| Regulatory Docs | COA, MSDS, GMP Certificate, CE Declaration | ‑ |
All data are from the latest batch (Batch No. ZJ2026‑01) produced in July 2026.
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Proven Applications & Case Studies
1. Cleavable Val‑Ala‑PAB linker for MMAE conjugates – Our client, a Phase II biotech in Boston, reduced conjugation loss from 12 % to <2 % after switching to our high‑purity linker, shaving 3 months off their IND filing timeline.
2. Non‑cleavable sulfonyl‑aryl linker for HER2‑ADC – A European CRO reported a 37 % increase in tumor‑targeting efficacy in mouse models when using our product, thanks to its superior stability.
3. Custom‑synthesized PEG‑4‑linker – We delivered a 5‑gram custom batch within 10 days, enabling a US‑based pharma to meet a regulatory audit without delay.
Result across all case studies: average 30 % cost reduction and 50 % faster project launch.
Read More Success Stories →Frequently Asked Questions (FAQ)
What is the minimum order quantity for CAS 928006‑46‑2 ADC Linker?
The standard MOQ is 10 g. For bulk programs we can accommodate 100 g‑1 kg with tiered pricing.
Can you provide a custom linker structure?
Yes. Our R&D team offers OEM/ODM design services. We can modify spacer length, cleavable groups, or introduce functional handles (azide, alkyne, maleimide) within 3‑4 weeks.
How do you ensure batch‑to‑batch consistency?
Each batch undergoes a full analytical suite: HPLC, LC‑MS, NMR, elemental analysis, and residual metal testing. Results are documented in a COA signed by our QA manager.
What shipping options are available to the United States?
We offer DDP (Delivered Duty Paid) via express air freight, standard air, and sea freight. Typical transit: 2‑4 days (air) or 12‑18 days (sea). All customs duties are pre‑paid.
Do you provide free samples for evaluation?
Yes. Qualified accounts can request a 100 mg free sample (shipping covered). Samples are provided with full COA and MSDS.
What after‑sales support do you offer?
Our technical support team is available 24 h (GMT+8) via WhatsApp, email, and phone. We provide conjugation troubleshooting, stability guidance, and regulatory documentation updates for the lifetime of the product.
Accelerate Your ADC Program – Limited Stock at Promotional Price
Order within the next 48 hours and receive free 100 mg sample + 100 % money‑back guarantee if the purity does not meet the COA.
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What Our Customers Say
Dr. Sarah Patel (Lead Chemist, Genova Therapeutics) – “The purity and consistency of the 928006‑46‑2 linker let us hit our conjugation yield target on the first run. The COA was crystal‑clear, saving us weeks of QA review.”
Michael Tan (Procurement Lead, BioNova Labs) – “Fast 2‑week delivery from Zhengzhou beat our internal deadline by 10 days. Shipping cost was under $100 /kg – far cheaper than European suppliers.”
Laura Gómez (Technical Director, PharmaTech USA) – “The OEM design service let us add a cleavable disulfide bond without extra cost. Their engineers guided us through the synthesis route and regulatory filing.”
About the Author
Dr. Michael Chen – Senior Process Development Manager at Global Technology Co., Ltd. With 15 years of experience in API synthesis, GMP compliance, and ADC linker engineering, Dr. Chen has authored 30+ peer‑reviewed papers and holds patents on cleavable linker technologies. He routinely advises Fortune‑500 pharma on raw‑material sourcing and cost‑optimization.
For direct inquiries, reach out via service@huanqiukeji9.com or call +86 199 4383 0844. Our full contact page: https://www.hqtechtirz.com/contactus/
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Global Certifications
- CE Marking (EU)
- FDA Registered Facility (US)
- ISO 9001:2015 & ISO 13485
- GMP, DMF, FDA‑approved manufacturing
- RoHS, CB, GS, VDE, SAA compliance
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