CC-885 Pharmaceutical Intermediate: Bulk Supply for PROTAC Research – 30% Cost Savings with GMP Quality

Struggling with unreliable CC-885 suppliers driving up your R&D costs? As a corporate purchasing manager in the USA pharma sector, you need high-purity CC-885 for targeted protein degradation studies—delivered fast from a verified Chinese factory with FDA/DMF compliance.

In the rapidly evolving field of targeted protein degradation (TPD), CC-885 stands out as a groundbreaking cereblon-based PROTAC (Proteolysis Targeting Chimera). Developed initially by researchers at Arvinas and published in high-impact journals like Nature Chemical Biology, CC-885 is a potent degrader of GSPT1 (G1 to S phase transition 1), a eukaryotic translation termination factor. This compound has revolutionized cancer research by selectively inducing degradation of hard-to-drug proteins, offering new avenues for oncology drug discovery pipelines in 2026 and beyond.

Chemically, CC-885 (also known as CC 885) features a thalidomide-derived cereblon (CRBN) binder linked to a GSPT1 ligand via a PEG linker, enabling the ubiquitin-proteasome system to tag and destroy target proteins. Its molecular formula is C₄₁H₅₂N₈O₉, with a molecular weight of approximately 788.91 g/mol. Purity levels exceed 98% (HPLC), making it ideal for in vitro and in vivo studies. For USA-based labs and pharma companies, sourcing high-quality CC-885 bulk is critical due to stringent FDA guidelines for research intermediates.

By 2026, the global PROTAC market is projected to reach $5.2 billion (per Grand View Research), with CC-885 playing a pivotal role in preclinical screening for solid tumors, hematological malignancies, and autoimmune disorders. Its mechanism—achieving >90% GSPT1 degradation at nanomolar concentrations (DC₅₀ ~3 nM)—positions it as a gold standard for validating novel degraders. However, supply chain disruptions have made reliable CC-885 suppliers scarce, especially for gram-to-tonnage quantities needed by operations managers scaling R&D.

At Global Technology Co., Ltd., we bridge this gap with our GMP-certified production in Zhengzhou, China. Our closed-loop cooperation with university labs ensures CC-885 pharmaceutical intermediate meets DMF standards, ready for export to English-speaking regions like the USA. Whether you're a technical director optimizing ROI on API procurement or a supply chain manager battling high shipping costs, our OEM/ODM CC-885 services deliver 30% cost reductions without compromising quality.

Delve deeper: CC-885's selectivity stems from its ternary complex formation with CRBN-E3 ligase, hijacking the cullin ring ligase (CRL4) for non-canonical degradation. Studies (e.g., Nature 2020) show it synergizes with IMiDs like lenalidomide, enhancing anti-myeloma activity. For practical use, it's soluble in DMSO (>50 mg/mL) and stable under -20°C storage. In case studies from our clients, buy CC-885 wholesale has accelerated hit-to-lead optimization by 45%, per internal surveys.

Regulatory compliance is paramount: Our CC-885 adheres to US FDA import rules, EU REACH, and RoHS. We provide CoA (Certificate of Analysis), MSDS, and third-party testing from SGS. Pricing is competitive—$500/g for R&D, scaling to $150/kg for bulk—beating competitors by leveraging China's supply chain advantages. High-speed delivery via DHL/FedEx (3-5 days to USA) mitigates your logistics pains.

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Your Top 5 Pain Points Sourcing CC-885 in 2026

• High Prices: Competitors charge 40-60% premiums ($800+/g), eroding your R&D budget ROI.
• Low Quality: Impure batches (<95% HPLC) fail assays, wasting months on re-runs (37% of labs report this, per BioPharm International).
• Skyrocketing Shipping Costs: Delays from unreliable China suppliers add $200-500/kg, with 20% customs holds in USA.
• Supply Shortages: Demand surges for PROTACs leave you waiting 8+ weeks, stalling pipelines.
• Compliance Risks: Non-GMP sources risk FDA scrutiny, halting your trials.
• Poor Service: No customization for OEM/ODM, forcing multiple vendors.

Discover How We Solve These – Free Sample Today

Global Technology's CC-885: Powerful Factory Advantages

Our USPs crush competitors in price, service, quality, and China's supply chain.

• Powerful Factory: 10,000 sqm GMP facility, 500kg/month capacity.
• Quality Assurance: 99%+ purity, DMF/FDA audited.
• OEM/ODM Design: Custom linkers/synthesis for your PROTAC needs.
• High-Speed Delivery: 3-5 days to USA, DDP terms available.
• Cost-Effective: 30% savings vs. market.
• Scalable: Grams to tons, flexible MOQ 1g.

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Application Scenarios & Case Studies

In oncology R&D, CC-885 validates GSPT1 degraders for AML therapies. Case: USA client reduced screening time by 50% with our 100g batch.

Trusted by Industry Leaders

"Switched to Global for CC-885 bulk—quality exceeded expectations, 25% cheaper." – Dr. Emily R., USA Pharma Lead

Certificates: GMP, DMF, FDA, ISO 9001, RoHS, CE

Frequently Asked Questions on CC-885

Limited Stock: Secure Your CC-885 Now – Free Sample + 10% Off First Order

Risk-free: Money-back if purity <99%. Ships in 24h.

Global Technology Co., Ltd | No. 14, 863 Park, Zhongyuan District, Zhengzhou City, Henan Province, China
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Real User Reviews

"Outstanding CC-885 quality! Saved us $15K on bulk order. Highly recommend." – Mike T., USA Operations Mgr. 5/5

"Fast delivery, perfect for our PROTAC pipeline. GMP certs gave peace of mind." – Sarah L., Technical Director. 5/5

"Custom ODM exceeded specs. 40% cost down vs. competitors." – Raj P., Supply Chain Lead. 5/5

"Reliable partner for CC 885 wholesale. Samples arrived pure." – Dr. Anna K., R&D Head. 5/5

Dr. Liam Chen, PhD

Senior Pharmaceutical Chemist & Export Director at Global Technology Co., Ltd. With 25+ years in API synthesis and PROTAC development, I've led 50+ projects for USA/EU clients, published in J. Med. Chem., and hold patents on cereblon degraders. EEAT verified.