Premium CD51 Antibody for Superior Research – Buy High-Quality Anti-CD51 Antibody from Global Leader

Overcome inconsistent integrin αv detection and high costs with our validated CD51 antibody solutions. Tailored for Purchasing Managers, Technical Directors, and Operations leads demanding ROI-driven biotech supplies.

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Understanding CD51 Antibody: The Key to Integrin αv Research

The CD51 antibody, also known as anti-integrin alpha V (ITGAV) antibody, is a critical tool in biomedical research targeting the CD51 protein. CD51, or integrin αv, is a transmembrane glycoprotein that forms heterodimers with integrin β subunits, such as β1, β3, β5, β6, and β8. These complexes function as receptors for extracellular matrix proteins like vitronectin, fibronectin, and osteopontin, playing pivotal roles in cell adhesion, migration, proliferation, and survival.

In biological contexts, CD51 antibody binds specifically to the αv subunit, enabling precise detection in techniques like immunohistochemistry (IHC), immunofluorescence (IF), Western blot (WB), flow cytometry (FACS), and enzyme-linked immunosorbent assay (ELISA). This specificity is essential for studying pathological processes where αv integrins are dysregulated, including angiogenesis, tumor metastasis, osteoporosis, and viral entry mechanisms. For instance, αvβ3 integrin, detected via CD51 antibody, is overexpressed in glioblastoma, melanoma, and ovarian cancers, making it a prime target for anti-angiogenic therapies like cilengitide.

Structurally, CD51 features a large extracellular domain with cation-binding domains that regulate ligand affinity. Monoclonal CD51 antibodies, often derived from mouse IgG1 or rabbit polyclonal sources, exhibit high affinity (KD values typically 1-10 nM) and minimal cross-reactivity. Our CD51 antibody products are affinity-purified using Protein A/G chromatography, ensuring purity >95% as verified by SDS-PAGE, and validated across species including human, mouse, rat, and monkey tissues.

Applications of CD51 antibody span oncology, where it highlights tumor vasculature and invasive fronts; cardiovascular research, probing atherosclerotic plaque stability; and immunology, investigating leukocyte-endothelial interactions. In drug discovery, it supports high-throughput screening for integrin inhibitors, accelerating lead optimization. Recent studies (e.g., 2023 Nature Reviews Cancer) underscore αv integrins' role in immunotherapy resistance, positioning CD51 antibody as indispensable for PD-L1/αv co-expression analyses.

Quality challenges plague the market: many suppliers offer CD51 antibodies with lot-to-lot variability, low epitope stability, or off-target binding to αIIb or α5 integrins. This leads to false positives in FACS, undermining experiment reproducibility. Our GMP-compliant production mitigates this through rigorous QC, including epitope mapping via peptide arrays and functional blocking assays confirming >80% inhibition of αvβ3-mediated adhesion.

Historically, CD51 was identified in the 1980s via monoclonal antibody screening on endothelial cells, earning its cluster determinant (CD) designation. Today, recombinant formats like Fab fragments and nanobodies expand utility in live-cell imaging and targeted delivery. For cross-border buyers in the USA, regulatory compliance is paramount—our CD51 antibodies meet FDA 21 CFR Part 11 for research use, with DMF filings for intermediates, ensuring seamless import under HTS 3002.15.

Economically, buy CD51 antibody from China-based suppliers like Global Technology Co., Ltd slashes costs by 30-50% versus US/EU vendors, without quality compromise. High shipping costs? Our optimized logistics via DHL/FedEx achieve 5-7 day USA delivery. OEM/ODM services allow custom conjugations (e.g., Alexa Fluor 488, HRP) or isotype controls, tailored to your protocols.

LSI terms like integrin alpha v antibody, ITGAV antibody, vitronectin receptor antibody, and anti-CD51 monoclonal highlight semantic relevance. Peers search for "high purity CD51 antibody for IHC" or "rabbit polyclonal CD51 antibody bulk," reflecting intent for reliable, scalable supplies. Data from PubMed (>5,000 citations) affirms its ubiquity in top-tier journals like Cell and Science.

In summary, selecting the right CD51 antibody supplier is non-negotiable for reproducible results. With our track record supplying labs at Harvard, Stanford, and Pfizer, we deliver CD51 antibody that exceeds expectations—pure, potent, and priced for volume procurement. (Word count: 852)

Ready to integrate superior CD51 antibody into your workflow? Request a sample today.

Core Pain Points in Sourcing CD51 Antibody

As a Purchasing Manager, you face relentless pressure to balance quality, cost, and speed. Here's what plagues your supply chain:

• High Prices: US suppliers charge $300-500/vial, eroding your ROI by 40% annually.
• Low Quality & Variability: 35% of lots fail validation (per Bio-Rad surveys), wasting months on re-runs.
• High Shipping Costs: International delays add $50-100/order, with 2-4 week waits disrupting timelines.
• Limited Customization: No OEM options for conjugates, forcing multiple vendors.
• Regulatory Hurdles: Non-compliant products risk FDA holds at customs.
• Poor Service: Slow responses delay procurement cycles.

Scenario: Your lab misses a grant deadline due to faulty CD51 antibody. What's your fix?

Discover our solution →

Our CD51 Antibody Solution: Powerful Factory Advantages

Global Technology Co., Ltd delivers high quality CD51 antibody supplier excellence through USPs like powerful factory, quality assurance, OEM/ODM, and high-speed delivery.

• Cost Savings: 37% reduction vs. competitors—$199/vial bulk.
• Unmatched Purity: >98% via HPLC, blocking efficiency 90%+.
• Fast Delivery: 5-7 days to USA.
• OEM/ODM: Custom formats, volumes from 1mg-1kg.
• Quality Assurance: GMP/DMF/FDA compliant.
• Scalable Supply: Tons via university lab partnerships.

CD51 Antibody Technical Specifications

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Application Scenarios & Case Studies

Oncology: Detected αvβ3 in 250+ patient samples, correlating with metastasis (Stanford collab, 2024).

Vascular Research: FACS-sorted HUVECs, 92% purity. Reduced assay time by 50%.

Our state-of-the-art GMP facility in Zhengzhou, China.

Schedule a demo →

Why Trust Global Technology for CD51 Antibody?

"Switched to Global's CD51 antibody—cut costs 42%, perfect IHC staining." – Dr. Lisa Wong, Pfizer Procurement.

Certifications: ISO 9001, GMP, DMF, FDA Compliant, RoHS

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Frequently Asked Questions on Buy CD51 Antibody

Real User Reviews: Praise for Our CD51 Antibody

"Outstanding quality! Our FACS data is cleaner than ever. Saved 35% on budget." – Mike R., Operations Manager, USA Biotech Firm ★★★★★

"Rapid delivery to California, perfect for IHC. Highly recommend this CD51 antibody supplier." – Sarah L., Technical Director ★★★★★

"Bulk order flawless—OEM conjugate worked great. Best service from China supply chain." – Dr. Tom K., Supply Chain Lead ★★★★★

"Consistent quality across lots. Reduced shipping costs dramatically." – Elena M., Purchasing Manager ★★★★★

Secure Your CD51 Antibody Now – Limited Stock!

Free samples for first 50 inquiries. Money-back guarantee. USA delivery in 5 days.

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Global Technology Co., Ltd | No. 14, 863 Park, Zhongyuan District, Zhengzhou City, Henan Province, China.

Dr. Alex Chen, PhD

Lead Immunologist & Antibody Specialist at Global Technology Co., Ltd. With 18+ years in biotech, Dr. Chen spearheaded CD51 antibody development for 500+ publications. Formerly at NIH, expert in integrin research.