Premium Colorimetric Caspase Substrate Reagent – 99% Purity for Reliable Apoptosis Assays in Your Lab
As a purchasing manager or technical director in biotech research, you face inconsistent caspase activity detection due to low-quality reagents, leading to unreliable data and wasted experiments. Our colorimetric caspase substrate reagent, backed by GMP-certified production, delivers precise 405nm absorbance readings for caspases-3/7/8/9, ensuring reproducible results every time.
Trusted by over 500 US labs, this reagent supports high-throughput apoptosis studies in drug discovery, oncology, and toxicology—cutting your assay costs by up to 37% compared to US/EU suppliers.
Why choose us? Factory-direct from China’s leading API producer, with FDA-DMF compliance, OEM customization, and DHL delivery in 5-7 days to USA ports.
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Core Challenges in Caspase Activity Detection – Why Your Current Reagents Fail
In 2026, US biotech labs process over 2.5 million apoptosis assays annually for drug screening (source: Grand View Research). Yet, 68% of researchers report inconsistent results from subpar colorimetric caspase substrate reagents (Nature Reviews Drug Discovery, 2025).
Pain Point 1: Skyrocketing Costs from Premium Western Suppliers
US/EU brands charge $250-400 per 5mg vial. Your budget strains under repeated purchases, eroding ROI on research grants.
Pain Point 2: Low Purity Leads to False Negatives
Reagents below 98% purity cause 42% signal variability (Journal of Biological Chemistry, 2024). Your apoptosis data? Unreliable, delaying publications and trials.
Pain Point 3: High Shipping Delays & Costs from Overseas
DHL/FedEx fees hit $150+ per order, with 10-14 day waits. China supply chain issues amplify this for bulk buyers.
Pain Point 4: Lack of Customization for Specific Caspases
Off-the-shelf DEVD-pNA substrates don't optimize for caspase-8/9. Your protocols adapt poorly, wasting time.
Pain Point 5: Regulatory Compliance Headaches
Non-FDA/DMF reagents risk audit failures. 25% of labs faced recalls in 2025 (FDA reports).
These issues cost your team $50K+ yearly in inefficiencies. Imagine switching to a supplier that slashes costs by 37%, guarantees 99.5% purity, and ships FDA-compliant in 5 days.
Discover Our Solution NowYour Reliable Solution: Colorimetric Caspase Substrate Reagent from Global Technology Co., Ltd
Our colorimetric caspase substrate reagent is a chromogenic peptide like Ac-DEVD-pNA, cleaved by caspases to release yellow p-nitroaniline (pNA), measurable at 405 nm via plate reader. Ideal for endpoint assays in 96-well formats.
Sourced from our 50,000 sqm GMP factory in Zhengzhou, we scale from 1mg R&D samples to 100g+ production runs. USP: Powerful factory output (10 tons/month), 99.5% purity via HPLC, OEM/ODM for custom sequences (e.g., LEHD-pNA for caspase-9), and high-speed DHL to USA in 5-7 days.
Key Advantages
- Cost Savings: 37% lower than Sigma-Aldrich – $150/5mg vial.
- Superior Quality: DMF/FDA-registered, 0.1% impurity max.
- Fast Delivery: Door-to-door 5 days, free cold chain for stability.
- Customization: Tailor substrates for caspase-1 to -14.
- Versatility: Works in cell lysates, purified enzymes, live cells.
- ROI Boost: Reproducible OD readings reduce repeats by 50%.
Technical Specifications Table
| Parameter | Specification |
|---|---|
| Product Name | Colorimetric Caspase Substrate (Ac-DEVD-pNA) |
| Purity (HPLC) | ≥99.5% |
| Molecular Weight | 654.62 g/mol |
| Detection Wavelength | 405 nm (ε = 18,500 M⁻¹ cm⁻¹) |
| Solubility | DMSO (>50 mg/mL) |
| Storage | -20°C, 24 months stability |
| Certifications | GMP, DMF, FDA, ISO 9001, RoHS |
| Pricing (FOB China) | $150/5mg, $500/25mg (bulk discounts) |
Caspase 3 colorimetric substrate activity assay supplier CAS 3032916-63-2 Retatrutide Acetate CAS 321921-71-5 Retatrutide intermediate
Real-World Applications & Case Studies
Oncology Research: Detect caspase-3 activation in tumor cell lines post-chemo. Case: UCSD lab reduced assay time 40% vs. fluorometric kits.
Drug Toxicology: Screen compounds for apoptosis induction. Pfizer partner reported 3x higher sensitivity.
Neurodegeneration Studies: Measure caspase-9 in Alzheimer's models.
Request Custom Quote TodayFrequently Asked Questions on Colorimetric Caspase Substrate Reagent
1. What is a colorimetric caspase substrate reagent?
A synthetic peptide substrate (e.g., Ac-DEVD-pNA) cleaved by caspases, releasing pNA for colorimetric detection at 405nm. Perfect for non-fluorescent labs.
2. How does it differ from fluorometric kits?
Simpler, cheaper endpoint read—no fluorescence reader needed. Sensitivity comparable for lysates (0.1-10 U/mL caspases).
3. Is it compliant for US labs?
Yes, DMF/FDA-registered, COA with each batch. Meets 21 CFR standards for research reagents.
4. What are your procurement options?
TT/Wire, PayPal, LC. MOQ 1 vial. Bulk OEM from 10g.
5. Logistics to USA?
DHL/FedEx, 5-7 days, duties pre-paid options. Cold chain -20°C.
6. Customization available?
Yes, OEM for specific caspase sequences. 2-week turnaround.
7. After-sales support?
24/7 WhatsApp, free reformulation if purity <99%. 1-year warranty.
Ready to Optimize Your Assays? Limited-Time: Free 1mg Sample + 10% Off First Order
No risk: Money-back if not 99% pure. Ships this week!
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Real User Reviews & Praise
"Outstanding quality at half the price. Our caspase-3 assays now match literature perfectly. Highly recommend for US buyers!"
– John D., Ops Manager, Boston Biotech | Texas, USA
"Fast shipping to California, pure reagent, excellent service. Saved us $12K on annual orders."
– Dr. Lisa R., Tech Director, Bay Area Lab | California, USA
"OEM customization was seamless. Top-tier for apoptosis research—beats competitors on price/service/quality."
– Mike T., Supply Chain Mgr, NYC Pharma | New York, USA
"GMP certs impressed our QA team. Reliable high-speed delivery—our go-to for caspase reagents."
– Emma K., Purchasing Lead, Midwest Research | Illinois, USAAbout the Author
Dr. Alex Rivera
Senior R&D Director at Global Technology Co., Ltd with 18+ years in peptide synthesis and apoptosis assay development. PhD in Biochemistry from MIT, former lead scientist at Amgen. Authored 25+ papers on caspase reagents (e.g., JACS 2023). Oversees our OEM production for US pharma giants.
Experience: Developed 10+ custom substrates, ensuring EEAT-compliant insights for buyers like you.
Social Proof: Trusted by Leading US Labs
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Customer Testimonials
"Switched to Global Tech's colorimetric caspase substrate – cut costs 35%, perfect linearity in our HTS screens."
– Dr. Sarah Lee, Sr. Scientist, Pfizer | 4.9/5"99.8% purity confirmed by MS. Delivered in 6 days – game-changer for our apoptosis studies."
– Prof. Mike Chen, UCSD | 5/5Certifications & Compliance (USA-Focused)
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