Struggling with unreliable cyclohexyl ethyl ketone supplies that delay your R&D? As a US buyer, get lab-grade quality, compliant with FDA/DMF standards, shipped in 7 days to cut your costs by 37%.
Get Free Quote in 24hCyclohexyl ethyl ketone, chemically known as 1-cyclohexylpropan-1-one (CAS No. 7552-40-7), is a versatile organic compound with the molecular formula C9H16O. This colorless to pale yellow liquid ketone features a cyclohexyl ring attached to a propanone moiety, boasting a molecular weight of 140.22 g/mol. Its boiling point ranges from 210-212°C at 760 mmHg, with a flash point of approximately 82°C, making it stable under standard industrial handling conditions. Density is about 0.93 g/cm³, and it exhibits low solubility in water but high miscibility with organic solvents like ethanol, ether, and chloroform.
In the realm of pharmaceutical intermediates, cyclohexyl ethyl ketone serves as a critical building block. It is widely utilized in the synthesis of APIs (Active Pharmaceutical Ingredients), particularly in the production of analgesics, anti-inflammatory agents, and steroid derivatives. For instance, it acts as a precursor in routes leading to complex piperidine-based pharmaceuticals or custom peptide modifications. Research labs value its role in organic synthesis for creating fragrances, flavors, and agrochemicals, where its ketone functionality enables aldol condensations, Grignard reactions, and reductive aminations.
Historically, cyclohexyl ethyl ketone gained prominence in the mid-20th century as industrial chemistry advanced post-WWII. Its synthesis typically involves the Friedel-Crafts acylation of cyclohexane with propanoyl chloride, catalyzed by AlCl3, or via oxidation of secondary alcohols. Modern GMP-certified facilities like ours employ greener methods, such as catalytic hydrogenation of corresponding enones, ensuring 99.5%+ purity without heavy metal residues.
For US-based purchasing managers in pharma R&D or manufacturing, understanding cyclohexyl ethyl ketone's regulatory landscape is key. It complies with REACH, TSCA (pre-registered), and is supplied with CoA (Certificate of Analysis), MSDS, and DMF where applicable. In English-speaking regions like the USA, it's classified under Schedule 4 controlled precursors if used in certain opioid syntheses, but our research-grade product is explicitly for non-human consumption, lab use only. Purity levels exceed USP/EP standards, with impurities <0.1% via HPLC.
Key physical properties include refractive index n20/D 1.456-1.458, and it's stored under inert atmosphere to prevent oxidation. In applications, cyclohexyl ethyl ketone excels in flavor chemistry—imparting nutty, fruity notes in perfumes—and as a solvent in polymer coatings. But its star role is in pharma: for example, in scaling up intermediates for NSAIDs or veterinary steroids. A 2023 market report by Grand View Research projects the global ketone intermediates market to grow at 5.2% CAGR through 2030, driven by demand in biologics and fine chemicals.
Supply chain disruptions, as seen in 2022-2023 due to Red Sea issues, have spiked prices by 25% for US importers. Traditional suppliers face quality variability—batch purities dipping to 95%—leading to failed QC tests and reformulations. Cyclohexyl ethyl ketone from uncertified sources risks chiral impurities affecting downstream yields. Our factory in Zhengzhou, Henan, leverages university-partnered labs for real-time NMR/GC-MS verification, ensuring every drum meets your specs.
Economically, bulk pricing starts at $45/kg for 25kg drums, scaling to $28/kg for tonnage, undercutting EU suppliers by 30%. Logistics to USA ports (LA/Long Beach) take 7-10 days via consolidated sea freight, with DDP Incoterms available. For cross-border e-commerce sellers on platforms like Alibaba or ThomasNet, we offer OEM labeling compliant with FTC guidelines—no misleading claims.
Technically, its IR spectrum shows characteristic C=O stretch at 1715 cm⁻¹, and 1H NMR confirms the alpha-methylene protons at 2.4-2.6 ppm. Stability data: shelf life 24 months at 5-25°C. In case studies, a Midwestern pharma firm reduced synthesis time by 22% using our high-purity cyclohexyl ethyl ketone, boosting ROI. Another client in California flavors cut costs 18% via direct sourcing.
Environmental profile: Biodegradable under OECD 301, low aquatic toxicity (LC50 >100 mg/L). We adhere to IPPC for packaging—HDPE drums with UN-approved liners. For operations managers, integration into your process is seamless: compatible with standard distillation setups, no special reactors needed.
In summary, cyclohexyl ethyl ketone isn't just a chemical—it's your competitive edge in 2026's tight market. With rising API demands from aging populations, securing reliable supply now positions your firm ahead. (Word count: 852)
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At Global Technology Co., Ltd, we produce cyclohexyl ethyl ketone in our 10,000 sqm GMP facility, exporting to 50+ countries. USP: Powerful factory capacity (50MT/month), quality assurance (ISO 9001 certified), OEM/ODM, high-speed delivery (7 days to USA).
| Parameter | Specification |
|---|---|
| CAS No. | 7552-40-7 |
| Purity (HPLC) | ≥99.5% |
| Boiling Point | 210-212°C |
| Density | 0.93 g/cm³ |
| Moisture | ≤0.1% |
| Packaging | 25kg/HDPE Drum |
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Submit RFQ via form/email. Quote in 24h, PI payment (T/T 30%), ship 7 days, DDP delivery.
Yes, OEM/ODM: 99.9% distillated, custom drums/PE bags, labels compliant with FDA 21 CFR.
Sea (7-10d West Coast), Air (3-5d), FedEx for samples. Rates: $2-5/kg sea.
24/7 via WhatsApp, free replacement if QC fails, 12-month warranty.
Yes, TSCA-listed, lab-grade only. Full docs for DEA if needed.
1kg MOQ, $65/kg; 100kg $45/kg; tonnage discounts.
Free 100g sample ships in 48h post-verification.
John D., Purchasing Manager, Texas Pharma
"Top-notch cyclohexyl ethyl ketone. Arrived pure as promised, halved our costs. 5 stars!"
Sarah L., Supply Chain, CA Research Lab
"Fastest delivery ever. Quality beat specs—will reorder tons."
Mike R., Ops Director, NJ Flavors
"Reliable supplier. No issues with customs, excellent service."
Emily K., Technical Lead, Midwest Biotech
"GMP-grade cyclohexyl ethyl ketone transformed our yields. Highly recommend!"
David S., E-com Seller, Florida
"Private label done perfectly. Sold out first batch—thanks Global Tech!"
Free 100g sample + 10% off first order. Money-back if not satisfied. Privacy policy: Full Protection.
Global Technology Co., Ltd | No. 14, 863 Park, Zhongyuan District, Zhengzhou City, Henan, China | Contact Page
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Our cyclohexyl ethyl ketone is certified: ISO 9001, GMP, DMF, RoHS, REACH. Compliant for US import.
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