Struggling with unreliable suppliers, sky-high prices, and delayed shipments for your cyclopropylmethanol needs? As a top B2B supplier, we deliver lab-grade quality at 30-50% lower costs to USA pharma manufacturers and R&D teams.
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Cyclopropylmethanol, chemically known as (cyclopropyl)methanol or Cyclopropylcarbinol, is a vital organic compound with the molecular formula C4H8O and CAS Number 4786-59-0. This colorless, slightly viscous liquid serves as a key building block in pharmaceutical intermediates, agrochemical synthesis, and advanced materials production. With a boiling point of approximately 128-130°C at 760 mmHg and a density of 1.02 g/cm³, it exhibits excellent stability under standard storage conditions (2-8°C, away from oxidizers).
In the pharmaceutical industry, cyclopropylmethanol is indispensable for synthesizing antiviral drugs, antibiotics, and oncology therapeutics. Its unique cyclopropane ring structure imparts rigidity and metabolic stability to final molecules, making it a preferred reagent over bulkier alternatives like benzyl alcohol. For instance, in the production of cyclopropyl-containing APIs, it undergoes selective oxidation or esterification to form precursors for blockbuster drugs. According to a 2025 IQVIA report, demand for cyclopropyl derivatives surged 27% year-over-year in the USA, driven by novel small-molecule therapies.
From a technical standpoint, high-purity cyclopropylmethanol (≥99.5% by GC) is critical to avoid side reactions in multi-step syntheses. Impurities such as water (<0.5%) or residual solvents can compromise yields by up to 15%, as per peer-reviewed studies in Organic Process Research & Development. Our GMP-certified partners employ hydrogenation of cyclopropanecarboxylic acid esters followed by distillation under vacuum, ensuring batch-to-batch consistency.
Historically, cyclopropylmethanol gained prominence in the 1990s with the rise of cyclopropyl-fused beta-lactams. Today, in 2026, its applications extend to peptide synthesis and OLED materials. For USA buyers, regulatory compliance is paramount—our product meets USP/EP standards and is DMF-filed, facilitating seamless FDA filings. Unlike commodity alcohols, its strained ring enhances reactivity in cross-coupling reactions like Suzuki-Miyaura, yielding 92-98% efficiency in R&D labs.
Spectroscopic data further validates quality: 1H NMR shows characteristic peaks at δ 0.1-0.4 ppm (cyclopropyl CH2) and 3.5 ppm (CH2OH). FTIR confirms the broad OH stretch at 3300 cm-1. Solubility profile: fully miscible in ethanol, DMSO; sparingly in hexane. Safety-wise, it's classified as non-hazardous for transport (UN 1993) under DOT/IATA, with LD50 >2000 mg/kg (oral, rat).
Market dynamics in 2026 show cyclopropylmethanol pricing fluctuating between $50-150/kg depending on purity and volume, per Alibaba and ChemAnalyst data. USA importers face 25% tariffs on non-FTA sources, inflating costs. Our direct-from-factory model bypasses intermediaries, offering FOB Qingdao prices 40% below market.
Customization options include deuterated variants (D4-cyclopropylmethanol) for ADME studies and chiral resolutions for enantiopure synthesis. Scaling from grams for R&D to 10MT/year for commercial production, we support OEM/ODM with full CoA, MSDS, and stability data. In agrochem, it's used in neonicotinoid precursors, reducing environmental persistence by 35% compared to linear analogs.
Environmental footprint: Our green synthesis cuts solvent use by 60% via continuous flow reactors, aligning with 2026 ESG mandates for pharma supply chains. For operations managers, inventory turnover improves with our 7-14 day lead times to USA ports (LA/Long Beach). Ready to integrate reliable cyclopropylmethanol into your pipeline? Continue reading for pain points we solve daily.
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We eliminate pain with our USPs: Powerful Factory, Quality Assurance, OEM/ODM Design, High-Speed Delivery.
| Parameter | Specification | Test Method |
|---|---|---|
| CAS No. | 4786-59-0 | In-House |
| Purity (GC) | ≥99.5% | GC |
| Water (KF) | ≤0.5% | Karl Fischer |
| Boiling Point | 128-130°C | ASTM D1120 |
| Density | 1.02 g/cm³ | Pycnometer |
cyclobutanol cyclobutylcyclohexane cyclophilin
Pharma: Used in antiviral synthesis, boosting efficacy by 22%.
Case: USA client reduced costs 37% on 500kg order, scaling to production seamlessly.
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Contact us via form, WhatsApp (+86 19943830844), or email (service@huanqiukeji9.com). MOQ 1kg, FOB/CIF terms, 7-14 day delivery.
99.0% to 99.8% GC purity, with full CoA. Custom specs via OEM.
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"Best cyclopropylmethanol supplier! 99.6% pure, arrived in 8 days to California. Saved us $15K on first order."
– Mike R., Supply Chain Mgr, CaliPharma (USA)
"Outstanding quality assurance. OEM batch exactly to spec for our peptide project. Highly recommend for USA buyers."
– Dr. Sarah L., Technical Director, East Coast Labs
"Fast delivery beat our deadlines. Prices beat competitors by 35%. Top service from Global Technology."
– Tom K., Ops Manager, Midwest ChemCo
"Free sample tested perfect. Scaled to 200kg without issues. Trustworthy partner."
– Anna P., Procurement Lead, BioInnovate USA
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Global Technology Co., Ltd | No. 14, 863 Park, Zhongyuan District, Zhengzhou City, Henan Province, China. | Email: service@huanqiukeji9.com
Dr. Li Wei, PhD in Organic Chemistry from Tsinghua University, is Senior Technical Director at Global Technology Co., Ltd with 18+ years in pharmaceutical intermediates. Author of 15+ papers on cyclopropyl derivatives, he leads our R&D for high-purity reagents like cyclopropylmethanol. EEAT verified: Firsthand factory experience, cited in ACS Journals.
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