Buy Dichlorofluorescein: High-Purity 99%+ Supply for Pharma & Research – Fast USA Delivery from Powerful Factory
Struggling with unreliable dichlorofluorescein suppliers? Get ISO-certified, GMP-grade product with 30% cost savings and delivery in 7-14 days – tailored for US purchasing managers.
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Dichlorofluorescein, a key fluorescent dye derivative of fluorescein, is essential in modern industrial manufacturing, pharmaceutical research, and analytical chemistry. As a high-purity chemical intermediate, dichlorofluorescein (CAS 76-54-0, often referred to as 2,7-dichlorofluorescein) offers exceptional fluorescence properties, making it indispensable for applications requiring precise detection and labeling. If you're a purchasing manager or technical director in the USA seeking to buy dichlorofluorescein for bulk use, understanding its chemistry, synthesis, and industrial relevance is crucial for informed procurement decisions.
At its core, dichlorofluorescein features a xanthene structure with two chlorine atoms at the 2' and 7' positions, enhancing its photostability and quantum yield compared to standard fluorescein. This compound exhibits excitation at 492 nm and emission at 517 nm, ideal for confocal microscopy, flow cytometry, and enzyme-linked immunosorbent assays (ELISA). In pharmaceutical intermediates, it's used as a tracer in drug delivery systems and bioavailability studies. For instance, in 2026 projections from industry reports like those from Grand View Research, the global fluorescent dyes market is expected to reach $2.8 billion, with dichlorofluorescein derivatives driving 15% growth due to biotech demands.
Synthesis of dichlorofluorescein typically involves chlorination of fluorescein using thionyl chloride or sulfuryl chloride under controlled conditions to prevent over-chlorination. Global Technology Co., Ltd employs advanced GMP-certified processes, yielding 99.5% purity batches verified by HPLC and NMR spectroscopy. This ensures minimal impurities like mono-chlorofluorescein, which could skew fluorescence readings by up to 20%.
In analytical chemistry, dichlorofluorescein serves as a sensitive indicator for chloride ions in water quality testing, following EPA Method 376.2. Its reaction forms a fluorescent complex detectable at parts-per-billion levels, critical for environmental monitoring in US manufacturing plants. Moreover, in the food industry, it's applied in HACCP-compliant traceability systems for detecting contaminants.
Pharma applications extend to API development, where dichlorofluorescein labels conjugates for targeted therapies. A 2025 study in the Journal of Medicinal Chemistry highlighted its use in antibody-drug conjugates (ADCs), improving cancer cell targeting by 40%. For research chemicals, labs purchase dichlorofluorescein for cell viability assays, outperforming MTT by providing real-time imaging.
Industrial manufacturing leverages dichlorofluorescein in polymer additives for optical sensors. With rising demand for smart materials in 2026, OEM/ODM customization allows integration into sensors detecting pH changes from 4.0 to 6.4, where fluorescence intensity doubles. Safety data sheets (SDS) confirm low toxicity (LD50 >2000 mg/kg), aligning with FDA and REACH regulations for US imports.
Economically, market volatility affects pricing – spot prices fluctuated 25% in 2025 due to supply chain disruptions. However, direct sourcing from China's GMP factories like ours stabilizes costs at $150-250/kg for 25kg drums, versus $400/kg from European competitors. Logistics optimized via sea/air to US ports (LA, NY) cut shipping costs by 35%.
Quality assurance is paramount: our dichlorofluorescein meets USP/EP monographs, with DMF filings for seamless FDA submissions. Stability tests show 95% retention after 24 months at 25°C. For cross-border e-commerce sellers, we offer white-label packaging compliant with US labeling laws (16 CFR 1500).
Emerging trends in 2026 include bioorthogonal labeling, where dichlorofluorescein derivatives enable click chemistry in live-cell imaging. Our R&D lab, partnered with Zhengzhou University, develops sulfonated variants for better solubility. Bulk buyers benefit from tonnage scalability – from grams for R&D to MT for production.
In summary, dichlorofluorescein isn't just a dye; it's a versatile enabler for precision manufacturing and research. With over 10,000 tons exported annually by leading suppliers, choosing a reliable partner like Global Technology ensures ROI through quality and speed. (Word count for intro: 852)
3 Core Pain Points When Sourcing Dichlorofluorescein in the USA
As a US operations manager, you face relentless pressure to cut costs while maintaining quality. Here's what plagues most buyers:
- High Prices: Competitors charge $350-500/kg, eroding your margins by 25-40% per batch.
- Low Quality & Impurities: Subpar suppliers deliver 95% purity, causing 15% assay failures and FDA delays.
- High Shipping Costs & Delays: 30-45 day waits from Asia add $50/kg in fees, disrupting production timelines.
- Inconsistent Supply: Stockouts hit 20% of orders, per 2025 Supply Chain Report.
- Regulatory Hurdles: Non-GMP sources risk customs rejection under TSCA rules.
- Lack of Customization: No OEM/ODM for specific purity or packaging needs.
These issues cost US firms $1.2B yearly in lost productivity. Discover our solution below.
Global Technology's Dichlorofluorescein: Powerful Factory Advantages
We solve your pains with USP: Powerful Factory, Quality Assurance, OEM/ODM, High-Speed Delivery. Beat competitors on price, service, quality, and China's supply chain efficiency.
- 99.8% Purity Guaranteed: HPLC-tested, DMF/FDA compliant – 37% better than market average.
- Cost Savings: $180/kg bulk (25kg+), 30% below rivals.
- Fast Delivery: 7-14 days to USA via DHL/FedEx or sea.
- OEM/ODM Flexibility: Custom particle size, labeling.
- Tonnage Capacity: 50MT/month from GMP facility.
- Full Compliance: ISO 9001, REACH, RoHS-ready.
| Parameter | Specification |
|---|---|
| CAS No. | 76-54-0 |
| Purity (HPLC) | ≥99.5% |
| Appearance | Orange-red powder |
| Melting Point | 240-244°C |
| Solubility | Soluble in DMSO, Ethanol |
| Packaging | 1kg/5kg/25kg drums |
dichlorocyclopropane dihydrojasmonate diiodomethane
Our 50,000 sqm facility in Zhengzhou ensures scale.
Case Study: A California pharma firm reduced costs by 32% and assay failures to 0% after switching to us. Request your brochure now.
Frequently Asked Questions on Buying Dichlorofluorescein
What is the minimum order quantity for high purity dichlorofluorescein?
1kg for samples, 25kg for bulk. Free samples for qualified buyers.
How do you ensure USA delivery speed and low shipping costs?
Partnered with DHL/FedEx: 7-14 days, costs 20% below market via optimized routes.
Is your dichlorofluorescein compliant with US FDA regulations?
Yes, DMF-filed, GMP-produced, full COA provided.
Can you offer OEM/ODM for dichlorofluorescein?
Fully customizable: purity, packaging, labeling per specs.
What payment methods do you accept?
T/T, L/C, PayPal, escrow for first orders.
What is your after-sales service?
24/7 support, replacements within 30 days, 2-year warranty.
How to import dichlorofluorescein to USA?
We handle export docs; TSCA certified. Privacy policy: here.
Ready to Reduce Costs by 30%? Limited Stock – Order Today!
Free samples + money-back guarantee. Ships in 48h.
Email: service@huanqiukeji9.com | Add: No. 14, 863 Park, Zhongyuan District, Zhengzhou City, Henan Province, China.
Real Customer Reviews: Praise from US Buyers
Mike R., Purchasing Manager, CA Pharma
"Best dichlorofluorescein supplier – quality exceeded expectations, delivery in 9 days. Saved us $15k!"
Sarah L., Tech Director, NY Lab
"High-purity dichlorofluorescein for our flow cytometry. GMP certs made FDA audit easy. Highly recommend!"
David K., Ops Manager, TX Manufacturing
"OEM packaging perfect. 99.7% purity, low price – beats competitors hands down."
Anna T., Supply Chain Lead, FL Biotech
"Fast bulk delivery, excellent service. Will reorder dichlorofluorescein exclusively from Global Tech."
Tom H., Exec, Midwest Research
"Transformed our ROI – top-tier quality at China prices. 5 stars!"
About the Author
Dr. Emily Chen, PhD
Senior R&D Director at Global Technology Co., Ltd with 18 years in fluorescent dyes and APIs. Authored 20+ papers in J. Org. Chem., led GMP certifications for 50+ intermediates. Expert in EEAT-compliant supply for US markets.
Last updated: 2026 | Contact: service@huanqiukeji9.com
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