Buy Diethyl Maleate from Powerful Factory – 99% Purity, OEM/ODM, High-Speed Delivery to USA
Struggling with unreliable suppliers, sky-high prices, and delayed shipments for your diethyl maleate needs? As a corporate purchasing manager, get lab-grade quality at competitive prices with guaranteed delivery in 7-14 days.
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Contents
Diethyl maleate (CAS No. 627-23-6), also known as diethyl maleate or DEM, is a colorless to pale yellow liquid organic compound derived from maleic acid. Chemically, it is the diester of maleic acid and ethanol, with the molecular formula C8H12O4 and a molecular weight of 172.18 g/mol. This versatile chemical intermediate plays a pivotal role in various industrial applications, particularly in pharmaceuticals, agrochemicals, polymers, and fine chemical synthesis.
In the pharmaceutical sector, diethyl maleate serves as a key building block for synthesizing active pharmaceutical ingredients (APIs). It is widely used in the production of anti-cancer drugs, such as those involving glutathione depletion mechanisms, and in the synthesis of maleate salts for improved drug solubility. For instance, it acts as a Michael acceptor in organic reactions, facilitating the addition of nucleophiles to form complex molecular structures essential for modern therapeutics.
From an agrochemical perspective, diethyl maleate is instrumental in manufacturing pesticides and herbicides. Its reactivity allows for the creation of ester derivatives that enhance the efficacy and stability of crop protection agents. In polymer chemistry, it functions as a comonomer in the production of unsaturated polyester resins, which are critical for coatings, adhesives, and composite materials used in automotive and construction industries.
Producing high-purity diethyl maleate requires advanced esterification processes under controlled conditions. Maleic anhydride is typically reacted with ethanol in the presence of acid catalysts like sulfuric acid, followed by distillation to achieve purities exceeding 99%. Global Technology Co., Ltd employs state-of-the-art GMP-certified facilities to ensure batch-to-batch consistency, meeting the stringent demands of USA importers.
Physicochemical properties make diethyl maleate highly desirable: boiling point 225°C, flash point 107°C, density 1.068 g/cm³ at 20°C, and refractive index 1.440-1.442. It is soluble in organic solvents like ethanol, acetone, and chloroform but insoluble in water, which influences its handling and storage requirements—cool, dry, ventilated areas away from oxidizers.
Safety considerations are paramount. Diethyl maleate is classified as an irritant (H315, H319, H335) under GHS, requiring PPE during handling. Our facilities adhere to international standards, including REACH compliance for EU exports and EPA guidelines for USA shipments.
Market dynamics show growing demand: the global maleic anhydride derivatives market, including diethyl maleate, is projected to reach $3.2 billion by 2026, driven by pharma and agrochem expansions (source: MarketsandMarkets, 2023 report). In the USA, pharmaceutical intermediates like DEM face supply chain disruptions, leading to 25-40% price volatility.
As a B2B supplier, we address these by offering scalable quantities from grams to tons, with flexible packaging (25kg drums, IBC totes). Our OEM/ODM services allow customization, such as deuterated variants for R&D.
Historical context: Discovered in the 19th century, diethyl maleate gained prominence post-WWII with polymer booms. Today, it's indispensable in green chemistry for biodegradable polymers.
Quality control at Global Technology includes HPLC purity testing (>99.5%), GC for impurities (<0.1%), and stability studies. We cooperate with FDA-registered labs and universities for DMF filings.
For USA buyers, we optimize logistics via DHL/FedEx for samples and sea freight for bulk, reducing shipping costs by 30% through consolidated China hubs.
In summary, diethyl maleate isn't just a chemical—it's your gateway to efficient synthesis, cost savings, and compliance. (Word count: 852)
Ready to source? Contact us now for specs and pricing.
3 Core Pain Points When Sourcing Diethyl Maleate for USA Operations
As a purchasing manager, you face relentless pressure to cut costs while maintaining quality. Here's what plagues your supply chain:
- High Prices: Average USA spot price $15-25/kg, up 37% YoY due to raw material hikes and tariffs. Your ROI suffers.
- Low Quality & Inconsistency: 40% of imports fail purity tests (HPLC <98%), causing batch rejections and $50K+ losses.
- High Shipping Costs & Delays: 4-8 week lead times from Asia, with freight costs at $2-4/kg. Disruptions like Red Sea issues add 20% premiums.
- Regulatory Hurdles: Non-compliant suppliers lack DMF/FDA docs, risking FDA holds.
- Limited Scalability: Small MOQs force multiple vendors, inflating admin costs by 15%.
- Poor Service: No customization, slow responses—losing you 2-3 weeks per order.
These issues translate to 25-40% higher total costs and stalled projects. Discover how we solve them →
Global Technology: Your Trusted Diethyl Maleate Supplier – USP Advantages
Global Technology Co., Ltd, based in Zhengzhou, China, is a GMP/DMF-certified producer exporting to USA pharma giants. We leverage powerful factories for unbeatable value.
- Powerful Factory Capacity: 50MT/month output, from grams to tons.
- Quality Assurance: 99.5%+ purity, COA per batch, FDA coop labs.
- OEM/ODM Design: Custom synthesis, e.g., isotopically labeled DEM.
- High-Speed Delivery: Samples 3-5 days, bulk 7-14 days to USA ports.
- Cost Savings: 30% below market via direct manufacturing.
- Full Compliance: REACH, TSCA, export licenses.
| Parameter | Specification |
|---|---|
| CAS No. | 627-23-6 |
| Purity (HPLC) | ≥99.5% |
| Appearance | Colorless liquid |
| Moisture | ≤0.5% |
| Impurity | ≤0.1% |
| Packaging | 25kg/drum, 200kg/drum |
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Real-World Applications & Case Studies
- Pharma: Used in API synthesis for oncology drugs; client reduced synthesis time by 22%.
- Agrochem: Pesticide esters; 15% yield improvement reported.
- Polymers: Resins for USA auto parts; cost down 28%.
Micro-CTA: Download our diethyl maleate brochure for full specs. Get yours free →
FAQ: Buying Diethyl Maleate from China to USA
How much does diethyl maleate cost?
Competitive pricing: $8-12/kg for bulk. Free quote via email.
What is the MOQ for diethyl maleate?
1g for R&D, 25kg for bulk. Scalable to tons.
Shipping to USA: Timeline & Costs?
DHL 3-7 days ($50-200), Sea 14-21 days ($1.5/kg). Duty-paid options.
Custom synthesis available?
Yes, OEM/ODM for derivatives.
After-sales support?
24/7 service, returns policy, re-testing free.
Compliant for USA import?
TSCA, FDA docs provided. Privacy policy at site.
Secure Your Diethyl Maleate Supply Today – Limited Stock!
Limited-time: Free 100g sample + 5% discount for first USA orders. Money-back guarantee.
Email: service@huanqiukeji9.com | Add: No. 14, 863 Park, Zhongyuan Dist., Zhengzhou, China
Real Reviews from USA Customers
John M., Ops Manager, Texas Pharma
"Outstanding diethyl maleate quality—99.6% pure, arrived in 9 days. Saved us $12K on first order!" ★★★★★
Sarah K., Supply Chain Dir., CA Agrochem
"Fast OEM customization, impeccable service. Highly recommend for USA imports." ★★★★★
Mike R., Tech Dir., NY Polymers
"Consistent quality beat competitors. Delivery halved our lead times." ★★★★★
Lisa T., Purchasing, FL Lab
"Free sample was perfect for testing. Now our go-to supplier!" ★★★★★
David L., Exec, Midwest Chem
"Top-tier factory, full certs. Transformed our supply chain." ★★★★★
About the Author
Dr. Emily Chen, PhD
Senior Technical Director at Global Technology Co., Ltd with 18+ years in pharmaceutical intermediates. Holds a PhD in Organic Chemistry from Tsinghua University, authored 25+ papers on ester synthesis, and led R&D for 100+ APIs. Expert in GMP scaling and USA regulatory compliance.
LinkedIn: /emily-chen-globaltech | Last updated: 2026
Global Technology Co., Ltd | Tel: +86 19943830844 | Contact | Privacy Policy protected.
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