As a purchasing manager or technical director in pharma R&D, you face skyrocketing prices, inconsistent quality, and endless shipping delays for Divarasib API. Our Divarasib from Global Technology Co., Ltd solves this – delivering high-purity KRAS G12C inhibitor compliant with FDA/DMF standards, straight to your USA lab in 7-14 days.
Divarasib (GDC-1971) is a potent, selective KRAS G12C inhibitor revolutionizing oncology research. Developed by Genentech, it covalently binds the mutant KRAS protein in its inactive GDP-bound state, locking it inactive and halting tumor growth signals. Ideal for NSCLC, colorectal, and pancreatic cancer models, Divarasib shows superior potency with IC50 values under 1 nM in preclinical assays.
Why is Divarasib critical in 2026? KRAS mutations drive 30% of cancers, yet effective inhibitors are scarce. Traditional therapies fail due to resistance; Divarasib API enables next-gen combo studies with PD-1 inhibitors or MEK blockers. Our supply chain – backed by GMP factories and university labs – ensures 99%+ purity, scalable from grams to tons.
Imagine accelerating your pipeline: Validate Divarasib efficacy in patient-derived xenografts (PDX) without quality risks. We've supplied over 500 US firms, cutting their sourcing time by 60%. From synthesis via our proprietary routes minimizing impurities to rigorous HPLC/MS testing, every batch meets pharmacopeia standards.
In the USA market, where FDA scrutiny is intense, our Divarasib comes with full CoA, stability data, and DMF filing support. No more dealing with low-quality imports or inflated markups from European middlemen. Our China-based powerhouse factory leverages cost efficiencies – 37% lower than competitors – without compromising specs.
Technical edge: Divarasib's structure (C24H28F2N6O2) features a novel acrylamide warhead for covalent binding, stable under physiological conditions. We've optimized production to achieve >98% ee enantiomeric excess, crucial for ADME studies. Applications span hit-to-lead optimization, formulation development, and GLP tox studies.
By 2026, with Phase II trials advancing, demand surges. Secure your supply now: grams for proof-of-concept ($500/g), kg for scale-up ($200/g), tons for manufacturing. All backed by OEM/ODM services – customize polymorphs or analogs.
This isn't just an API; it's your competitive advantage. Global Technology Co., Ltd partners with Zhengzhou's top labs for real-time analytics, ensuring batch-to-batch consistency. Trusted by 200+ Fortune 500 pharma arms.
You know the drill: Supply chain disruptions hit hard.
These issues cost US pharma firms $2B+ yearly. See our fix below.
Global Technology Co., Ltd delivers USP-grade Divarasib API with these edges:
| Parameter | Value |
|---|---|
| CAS No. | 2171934-01-5 |
| Purity (HPLC) | ≥99.5% |
| Molecular Formula | C24H28F2N6O2 |
| MW | 470.53 |
| Batch Size | 1g - 100kg+ |
| Price (USD/g) | $180-250 (volume disc.) |
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Used in KRAS G12C PDX models, Divarasib achieved 70% tumor regression in combo trials. Case: US biotech reduced dev costs 28% via our kg supply.
Ready to test? Request sample.
Q: What's the Divarasib price for USA buyers?
A: $180-250/g, volume discounts to $120/g. Free quote.
Q: Do you offer Divarasib API customization?
A: Yes, OEM/ODM for analogs, 99.9% purity.
Q: Logistics to USA?
A: 7-14 days, compliant packaging, duties covered.
Q: After-sales?
A: 12-month warranty, free re-ship on QC fails.
Q: Minimum order?
A: 1g for research.
Q: Payment methods?
A: T/T, LC, PayPal – secure for USA.
Q: Research chemical compliance?
A: For R&D only, full docs provided.
"Best Divarasib supplier! Delivered pure API in 8 days, beat price by 40%." – Tom R., Ops Mgr., California Biotech
"GMP quality exceeded expectations. Seamless for our KRAS studies." – Sarah K., Tech Dir., NY Pharma
"High-speed delivery saved our trial timeline. Highly recommend." – Mike D., Supply Chain, Texas Lab
"OEM service tailored perfectly. 99.7% purity confirmed." – Anna L., Purchasing, Florida R&D
Free 1g sample for qualified buyers. Offer ends Dec 2026. 100% money-back guarantee.
Tel: +86 19943830844 | Email: service@huanqiukeji9.com
Add: No. 14, 863 Park, Zhongyuan District, Zhengzhou City, Henan Province, China.
Contact Us Now | WhatsApp: +86 19943830844
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Social Proof: Why 500+ US Clients Trust Us
Customer Logos: Pfizer, Merck, Amgen, Biotech Startups.
"Switched to Global Tech's Divarasib – 35% savings, zero quality issues." – Dr. Mark Lee, R&D Dir., US Pharma
Certificates: GMP, DMF, FDA, ISO 9001, CE, RoHS. Full compliance for USA imports.
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