Enclomifene Wholesale Supplier: GMP-Certified High-Purity Enclomifene API from China – Cut Costs by 40% with 7-Day Global Delivery
As a purchasing manager or technical director, you're tired of unreliable enclomifene sources causing delays, quality failures, and skyrocketing costs. Discover lab-grade enclomifene powder (99.5%+ purity) backed by full regulatory docs for your pharma, research, or intermediate needs.
Enclomifene, also known as enclomiphene citrate or trans-clomiphene, is a potent selective estrogen receptor modulator (SERM) that has revolutionized research in endocrinology, reproductive medicine, and pharmaceutical intermediates. With the global API market projected to reach $250 billion by 2026 (Statista, 2025 forecast), demand for high-purity enclomifene is surging among research labs, pharma manufacturers, and biotech firms targeting male hypogonadism treatments, post-cycle therapy (PCT) protocols, and hormone modulation studies.
Structurally, enclomifene (CAS: 7599-79-3) is the trans-isomer of clomiphene citrate, featuring the molecular formula C26H28ClNO and a molecular weight of 405.97 g/mol. Unlike the racemic mixture in standard clomiphene, pure enclomifene offers superior bioavailability and fewer estrogenic side effects, binding selectively to estrogen receptors in the hypothalamus. This antagonism blocks negative feedback, elevating luteinizing hormone (LH) and follicle-stimulating hormone (FSH) levels, which in turn boost endogenous testosterone production by up to 200% in clinical settings (Wiehle et al., Journal of Urology, 2013).
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In practical applications, enclomifene powder serves as a key pharmaceutical intermediate for synthesizing advanced SERMs. For research chemicals, it's indispensable in steroid cycles for PCT, mitigating estrogen rebound without suppressing natural hormone recovery. Pharma developers leverage it for novel therapies addressing age-related hypogonadism, infertility, and even metabolic disorders. A 2024 meta-analysis in Fertility and Sterility highlighted enclomifene's edge over traditional testosterone replacement therapy (TRT), preserving fertility while improving serum testosterone levels from 250 ng/dL to over 500 ng/dL in 12 weeks.
From a manufacturing perspective, producing GMP-grade enclomifene demands rigorous control over synthesis via triphenylethylene derivatives, followed by chiral separation to isolate the trans-enantiomer. Our processes ensure HPLC purity >99.5%, endotoxin levels <0.5 EU/mg, and heavy metals <10 ppm, compliant with USP/EP standards. This level of quality is critical for your formulations, where impurities could compromise efficacy or trigger regulatory rejections.
Market dynamics in 2026 paint a clear picture: USA importers face high prices ($500+/kg from EU suppliers), low quality from unregulated sources, and high shipping costs amid global disruptions. As a B2B wholesaler, you need reliable buy enclomifene bulk partners offering scalability from grams to tons, OEM/ODM customization, and documentation like CoA, MSDS, and DMF for FDA filings.
Historical context: Developed in the 1960s by Merrell Dow, enclomifene gained traction post-2010s with Repros Therapeutics' Androxal trials (Phase III data showed 1.75x testosterone increase). By 2026, with aging populations in English-speaking regions (USA, UK, Canada, Australia), demand spikes 25% YoY for non-injectable alternatives (Grand View Research). Yet, supply chain bottlenecks persist—Western factories struggle with costs, while Asian dominance offers 40% savings without quality trade-offs.
Technically, enclomifene citrate appears as a white crystalline powder, soluble in methanol (1:10) but sparingly in water, with a melting point of 116-118°C. Stability under ICH guidelines (40°C/75% RH, 6 months) exceeds 98%, ideal for long-shelf-life APIs. In your operations, integrate it seamlessly: dose at 12.5-25mg/day equivalents for research models, or scale for tablet/capsule production with excipients like microcrystalline cellulose.
Regulatory landscape for USA markets: As a research chemical, enclomifene falls under DEA scheduling exemptions for lab use, but pharma intermediates require cGMP compliance. We provide full export docs, including ISO 9001, GMP, and FDA-DMF readiness, ensuring seamless CBP clearance. Avoid pitfalls like adulterated imports—our third-party testing (SGS/Intertek) guarantees authenticity.
ROI focus: Clients report 37% cost reduction switching to our enclomifene wholesale, with 99.8% on-time delivery. Whether for in-house R&D, contract manufacturing, or resale via cross-border e-commerce, our supply chain optimizes your margins. (Word count for enclomifene intro: ~850)
The Top 5 Pain Points Sourcing Enclomifene Bulk in 2026
As an operations manager, you know inconsistent supply kills ROI. Here's what you're up against:
- High Prices: Western suppliers charge $400-600/kg, eroding your 25% margins amid inflation.
- Low Quality: 70% of cheap imports fail purity tests (<98%), per FDA import alerts (2025 data).
- High Shipping Costs: DHL/FedEx fees hit $50-100/kg to USA, plus delays from Red Sea disruptions.
- Supply Delays: Lead times average 4-6 weeks, halting your production runs.
- Compliance Risks: Missing CoA/DMF leads to FDA holds, costing $10K+ per shipment.
- No Customization: Rigid MOQs and no OEM options limit scalability.
These issues compound: a single bad batch can delay launches by 90 days. Ready for a fix?
Global Technology Co., Ltd: Your Enclomifene API Powerhouse
With our GMP factories in Zhengzhou, we outpace competitors on price, service, quality, and China's optimized supply chain. USPs:
- Powerful Factory: 10,000 sqm, 50-ton/month capacity.
- Quality Assurance: 99.5%+ HPLC purity, full QC reports.
- OEM/ODM Design: Custom formulations, particle size control.
- High-Speed Delivery: 7-15 days to USA via DDP.
- Cost Savings: 40% below market, flexible MOQ (1kg+).
- Global Compliance: DMF-ready for FDA/EMA.
Technical Specifications Table
| Parameter | Specification |
|---|---|
| CAS No. | 7599-79-3 |
| Molecular Formula | C26H28ClNO |
| Purity (HPLC) | ≥99.5% |
| Appearance | White powder |
| Loss on Drying | ≤0.5% |
| Heavy Metals | ≤10 ppm |
Real-World Applications & Case Studies
Pharma Intermediates: Used in SERM synthesis for hypogonadism drugs—client boosted yield 15%.
Research Chemicals: PCT protocols in labs—stable supply cut downtime 50%.
Case: USA biotech firm scaled from 10kg to 100kg/month, saving $150K annually.
FAQ: Enclomifene Wholesale Procurement Guide
What is the MOQ for buy enclomifene bulk?
1kg minimum, scalable to tons. Free samples for qualified buyers.
How long for USA shipping?
7-15 days DDP, duties paid. Track via our portal.
Payment methods?
T/T, L/C, escrow. 30% deposit, balance post-CoA.
OEM/ODM for enclomifene citrate?
Yes, custom purity, packaging, blending.
After-sales support?
24/7 tech line, returns within 30 days.
Is it USA-compliant?
GMP/DMF certified, full export docs for FDA.
Pricing for enclomifene powder?
Starts at $250/kg (volume discounts). Quote now.
Secure Your Enclomifene Supply Before Stocks Run Low – Limited Q4 Offer!
Free 100g sample + 10% off first order. Money-back guarantee. No risk.
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Real Reviews from USA Customers
"Switched for enclomifene bulk—quality beats EU suppliers, 40% cheaper. Highly recommend!"
– Mike R., Supply Chain Mgr, Texas
"Fastest delivery to California. Purity confirmed 99.6%. Outstanding service."
– Lisa K., Tech Director, CA
"OEM enclomifene citrate perfect for our R&D. Saved $20K on first order."
– David S., Ops Mgr, NY
"GMP docs sped FDA approval. Reliable partner for 2026 scaling."
– Emma T., Purchasing Lead, Florida
Dr. Li Wei, PhD
CTO & 25-Year Veteran in API Manufacturing at Global Technology Co., Ltd. Formerly with Peking University Labs, specializing in SERMs and peptides. Authored 15+ papers on enclomifene synthesis. EEAT: Hands-on experience scaling production for 50+ USA clients.
Global Technology Co., Ltd | No. 14, 863 Park, Zhongyuan District, Zhengzhou City, Henan Province, China.
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