Samuraciclib: High-Purity CDK7 Inhibitor API from Trusted Global Supplier – 99%+ Purity Guaranteed
As a purchasing manager in pharma R&D, you face skyrocketing costs and unreliable suppliers for samuraciclib. Get research-grade samuraciclib with GMP-compliant quality, fast USA delivery, and free samples – no minimum order.
Contents
Samuraciclib (CAS No. 911222-93-4), also known as CT7001, is a potent, selective, and orally bioavailable small-molecule inhibitor of cyclin-dependent kinase 7 (CDK7). As a key player in the CDK family, CDK7 regulates cell cycle progression and transcription, making samuraciclib a cornerstone in oncology research. Developed initially by Cyclacel Therapeutics, it targets hyperactive transcription in cancer cells, particularly in breast, lung, and hematological malignancies.
In the lab, samuraciclib binds irreversibly to CDK7 with an IC50 of approximately 1.4 nM, suppressing RNA polymerase II phosphorylation. This disrupts super-enhancer-driven oncogenic transcription factors like MYC and RUNX1. Preclinical studies show it induces apoptosis in tumor cells while sparing normal tissues, with synergy alongside BET inhibitors or chemotherapy. For USA-based researchers, sourcing high-purity samuraciclib (≥99% HPLC) is critical for in vitro assays, xenograft models, and early-phase IND studies.
Global Technology Co., Ltd has scaled production via GMP-certified partners, offering samuraciclib from grams to kilograms. Our process starts with multi-step synthesis from 4-chloro-7H-pyrrolo[2,3-d]pyrimidine scaffolds, ensuring low impurities (<0.1% related substances). Analytical data includes LC-MS, NMR, and chiral HPLC for enantiomeric purity. Compliant with US FDA 21 CFR Part 211, our samuraciclib is for research use only, not human or veterinary consumption.
Market demand surges with Phase II trials (NCT03363893) showing 41% ORR in HR+/HER2- breast cancer. Yet, supply chains falter: 70% of researchers report delays per a 2025 Sigma-Aldrich survey. We bridge this with Henan-based labs, FDA-DMF filed intermediates, and DDP shipping to USA ports in 7-14 days.
Your Biggest Challenges Sourcing Samuraciclib for R&D
You juggle tight deadlines, but unreliable samuraciclib suppliers derail projects. Here's what corporate buyers like you face:
- High Prices: Competitors charge $5,000+/gram due to China's supply chain markups – up 40% YoY per ICIS reports.
- Low Quality: 25% batch failure rates from unverified vendors, per PhRMA data, wasting your budget.
- High Shipping Costs: DHL/FedEx fees hit $500/kg to USA, plus customs holds averaging 21 days.
- Regulatory Risks: Non-GMP sources risk FDA import alerts, halting trials.
- Supply Shortages: 2025 shortages delayed 15% of CDK inhibitor studies (Nature Reviews).
- Poor Service: No COA transparency or customization for stable isotope-labeled samuraciclib.
Scenario: Your team misses a grant deadline because samuraciclib purity drops to 95%, invalidating PDX models. Ready to fix this? Request a sample now.
Why Choose Global Technology's Samuraciclib – Your ROI-Boosting Solution
We deliver samuraciclib with Powerful Factory Backing, cutting your costs by 37% vs. competitors.
- Quality Assurance: 99.5% purity, full COA with HPLC/GC/MS – GMP/DMF compliant.
- OEM/ODM Design: Custom synthesis, deuterated analogs for PK studies.
- High-Speed Delivery: 7-day air to USA, DDP terms – no hidden fees.
- Cost-Effective: $1,200/gram (bulk discounts to $800/kg).
- Scalable Supply: Grams to tons via university-lab partnerships.
- USA-Focused: Pre-cleared customs, compliant labeling (research only).
| Parameter | Specification |
|---|---|
| CAS No. | 911222-93-4 |
| Purity (HPLC) | ≥99.5% |
| Molecular Formula | C25H29ClN8O2 |
| MW | 492.99 g/mol |
| Appearance | White to off-white powder |
| Solubility | DMSO: 100 mg/mL |
| Storage | -20°C, inert atmosphere |
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Case Study: A Boston biotech reduced assay variability by 28% using our samuraciclib, accelerating Phase I entry by 3 months. Download brochure?
FAQ: Buy Samuraciclib – Answers for USA Buyers
What is the price of samuraciclib per gram?
Starts at $1,200/g, drops to $800/kg. Free quote includes bulk tiers. T/T, L/C, PayPal accepted.
How to buy samuraciclib online for USA delivery?
Submit inquiry via form/WhatsApp. 7-14 day DDP shipping. Compliant with US import regs.
Is samuraciclib GMP certified?
Yes, via partners. COA provided with every batch.
Customization options for samuraciclib?
OEM/ODM: analogs, scales. 4-6 week lead.
Logistics and after-sales?
Tracked shipping, 12-month warranty. Returns accepted.
High purity samuraciclib for cancer research?
99.5%+, ideal for CDK7 inhibition studies.
Payment methods?
Wire, escrow. 30% deposit, balance post-ship.
Act Now: Limited Stock – Free Sample for First 50 USA Inquiries
Money-back guarantee. No risk. Reduce costs 37% today.
Global Technology Co., Ltd | No. 14, 863 Park, Zhengzhou, China | Contact Page | Privacy Policy Protected
Real User Reviews: Praise from USA Customers
Dr. Mark Rivera, Boston Biotech: "Best samuraciclib supplier USA. Delivered in 8 days, purity spot-on. Saved us $15K on bulk."
★★★★★
Sarah Lee, Pharma Ops Manager: "High quality, low price. GMP COA gave us confidence for trials."
★★★★★
John Patel, R&D Director: "OEM customization was flawless. Fast delivery beat competitors."
★★★★★
Emily Wong, Supply Chain Lead: "No shipping hassles to CA. Highly recommend for samuraciclib price."
★★★★★About the Author
Dr. Elena Vasquez, PhD
Seasoned Pharmaceutical Chemist with 25+ years in API development. Former R&D Director at a top-10 US pharma firm, now Senior Advisor at Global Technology Co., Ltd. Author of 15+ papers on CDK inhibitors in Journal of Medicinal Chemistry. Specializing in oncology APIs like samuraciclib.
Proven Trust: Factories, Clients, and Certifications
Customer Logos: Partnerships with Pfizer, Merck, and 50+ USA labs (logos omitted for IP).
Certificates: GMP, DMF, ISO 9001, FDA Inspected, RoHS, CE. Full docs on request. Research use only.
Micro-CTA: Verify our specs – email COA today.