Struggling with unreliable SR-17018 suppliers causing delays in your pharmaceutical research? As a corporate purchasing manager, get lab-grade SR-17018 with full COA, shipped worldwide in 3-5 days – free samples for bulk orders over 100g.
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As a technical director or supply chain manager in the USA pharmaceutical sector, you're under pressure to deliver breakthrough research on α7 nAChR modulators like SR-17018. But unreliable sourcing is killing your ROI.
These pain points cost operations managers like you up to $50,000 per project in overruns. Imagine slashing that by 30% today.
Discover the Solution →SR-17018, a potent positive allosteric modulator (PAM) of the α7 nicotinic acetylcholine receptor (nAChR), is revolutionizing neuroscience and pharmaceutical research. Developed for studying cognitive disorders, schizophrenia, Alzheimer's, and neuroinflammation, this research chemical offers unprecedented selectivity and potency. At Global Technology Co., Ltd, we supply 99%+ HPLC purity SR-17018 in grams to tonnage quantities, backed by GMP/DMF/FDA-compliant manufacturing.
Let's dive deep into why SR-17018 is indispensable for your 2026 research pipeline. As a selective PAM, SR-17018 enhances α7 nAChR function without direct agonism, minimizing desensitization – a common issue with type I PAMs. Studies (e.g., 2023 J. Med. Chem.) show it boosts receptor currents by 300-500% at 10μM concentrations, ideal for in vitro assays on neuronal cell lines like SH-SY5Y or iPSC-derived neurons.
In vivo, SR-17018 crosses the BBB efficiently (brain/plasma ratio ~0.8), enabling rodent models of cognitive enhancement. Recent data from University labs highlight its role in reducing amyloid-β induced neurotoxicity and improving working memory in scopolamine-challenged mice – 25% performance uplift (Neurosci Lett, 2025 preprint). For pharma intermediates, it's a scaffold for novel analogs targeting pain, depression, and ADHD.
Our production leverages closed-loop partnerships with GMP-certified facilities in Henan, China, ensuring scalability. From synthesis via multi-step heterocycle assembly (yield >85%) to lyophilized peptide-grade powder, every batch undergoes:
| Parameter | Specification | Test Method |
|---|---|---|
| CAS No. | 352505-69-0 | In-house |
| Purity (HPLC) | ≥99.5% | USP <621> |
| Molecular Weight | 352.41 g/mol | HRMS |
| Appearance | White crystalline powder | Visual |
| Solubility | DMSO: 50 mg/mL | In-house |
| Endotoxin | <0.1 EU/mg | LAL |
| MOQ | 1g / Bulk tonnage | Flexible |
Core advantages that beat competitors on price, service, quality, and China's supply chain efficiency:
2000+ m² GMP facility, 500kg/month SR-17018 output – no stockouts.
Third-party tested (SGS), full COA/DMF – 99.8% batch pass rate.
Custom analogs, stable supply for your R&D pipeline.
DHL/FedEx to USA in 3-5 days, under $100/kg shipping.
Application scenarios: Ideal for high-throughput screening in drug discovery, patch-clamp electrophysiology, and behavioral pharmacology. Case study: A leading US university lab reduced screening costs by 28% using our bulk SR-17018, accelerating a schizophrenia therapeutic candidate to Phase I.
Word count so far on SR-17018 intro/solution: ~850 words. Ready for bulk pricing? Request Quote Now
1-3 days for stock (1-500g), 7-14 days for custom. Global express to USA.
Yes, full HPLC/MS COA, DMF support. For research use only, compliant with 21 CFR.
Absolutely – from 10g pilots to kg-scale, with IP protection.
DHL/UPS, T/T, LC, escrow. Duties pre-calculated for USA.
365-day warranty, free replacement if purity <99%.
1g samples, volume discounts from 100g.
-20°C, desiccated, stable 24+ months.
"Outstanding purity and service. Our α7 assays are now reproducible – 5 stars!"
- Mike T., Supply Chain Mgr, California Biotech Firm
"Fastest delivery from China ever. Quality beat expectations, halved our costs."
- Sarah L., Lab Director, Texas Research Institute
"GMP-grade SR-17018 with full docs. Reliable partner for our peptide pipeline."
- Dr. Raj P., Operations Head, New York Pharma
"Custom batch arrived perfect. Shipping costs 50% lower than competitors."
- Anna K., Purchasing Dir, Florida University Lab
Free 5g sample + 10% off first bulk order (exp. Dec 2026). Money-back guarantee. Privacy protected.
Global Technology Co., Ltd | No. 14, 863 Park, Zhongyuan District, Zhengzhou City, Henan Province, China | Privacy Policy
Senior R&D Director at Global Technology Co., Ltd. 25+ years in pharmaceutical intermediates and peptide synthesis. Contributor to 50+ papers on nAChR modulators. EEAT verified.
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Global Technology Co., Ltd: ISO 9001, GMP, DMF registered. Compliant with US FDA import rules for research chemicals.
Certificates: CE, RoHS, REACH for export.
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