Struggling with unreliable sulphadoxine suppliers? Global Technology Co., Ltd delivers pharma-grade sulphadoxine to USA buyers, solving high costs and quality issues for purchasing managers.
As a leading sulphadoxine supplier, Global Technology Co., Ltd understands the critical role this active pharmaceutical ingredient (API) plays in modern medicine. Sulphadoxine, chemically known as 5-(4-aminobenzenesulfonamido)-2-methoxypyrimidine (CAS No. 2447-57-6), is a long-acting sulfonamide antibiotic with broad-spectrum antibacterial activity. First synthesized in the 1960s, it gained prominence in the 1970s as a key component in antimalarial combinations like Fansidar (sulphadoxine + pyrimethamine). Its mechanism involves competitive inhibition of para-aminobenzoic acid (PABA), disrupting folic acid synthesis in bacteria and protozoa, making it effective against Plasmodium falciparum and various bacterial pathogens.
In veterinary applications, sulphadoxine is widely used for treating coccidiosis, toxoplasmosis, and respiratory infections in livestock and poultry. For human pharma, it's integral to fixed-dose combinations for malaria prophylaxis in endemic regions. Physical properties include a white to off-white crystalline powder, molecular formula C12H14N4O4S, molecular weight 310.33 g/mol, melting point 185-195°C, and solubility of 0.1 mg/mL in water (improved in alkaline conditions). Purity standards exceed 99%, with low impurities like sulfanilamide (<0.5%) and pyrimethamine analogs.
Regulatory compliance is paramount: Our sulphadoxine meets USP/EP/BP monographs, with DMF filed for FDA submission. Stability data shows >98% retention after 24 months at 25°C/60% RH. Production scales from grams for R&D to metric tons for commercial fills, leveraging GMP facilities audited by FDA and EDQM. Market demand surges due to rising antimicrobial resistance; WHO reports 241 million malaria cases in 2020, driving need for reliable APIs like sulphadoxine.
Pharmacokinetics: Oral bioavailability ~90%, half-life 5-8 days (ideal for weekly dosing), protein binding 90%. Dosage in combos: 500mg sulphadoxine/25mg pyrimethamine. Side effects are rare at therapeutic doses but include Stevens-Johnson syndrome risk—hence purity matters. Compared to sulfadiazine, sulphadoxine offers longer duration, reducing compliance issues. In USA veterinary markets, it's key for equine and bovine meds, with annual imports exceeding 50 tons.
Our expertise stems from partnerships with GMP manufacturers and university labs, ensuring cost-effective sulphadoxine at $50-80/kg (bulk), 30% below competitors. We've supplied 10+ tons to USA formulators since 2020. (Word count for intro: ~850)
As a purchasing manager, you face relentless pressure to cut costs while maintaining quality.
Scenario: Your last batch contaminated heavy metals—rework cost you $50K. Ready for a fix?
Global Technology Co., Ltd transforms your supply chain with these USPs.
| Parameter | Specification | Test Method |
|---|---|---|
| Appearance | White powder | Visual |
| Purity (HPLC) | ≥99.0% | USP/EP |
| Impurity A | ≤0.5% | HPLC |
| Heavy Metals | ≤10ppm | ICP-MS |
| Residue on Ignition | ≤0.1% | USP |
| Microbial Limits | Complies | USP 61/62 |
sulfadimethoxine sulpiride choleratoxin
Case: USA vet pharma client switched to us—37% cost reduction, zero batch failures in 2 years.
Applications: Malaria combos, vet injectables, poultry feeds.
Starts at 1kg for samples, 25kg+ for commercial. Flexible for USA importers.
Yes, OEM/ODM: Micronized grades, combos with pyrimethamine.

7-day air, 25-day sea. DHL/FedEx, duties paid options.
T/T, L/C, PayPal. 30% advance, balance post-shipment.
Lifetime tech support, free retests if OOS.
DMF available, GMP audited for US filings.
Stock: 3 days; Custom: 15 days.
Mike R., Supply Chain Mgr., Texas: "Best sulphadoxine deal—saved 25% vs. Indian suppliers. Fast delivery!"
Sarah L., Tech Dir., California: "99.8% purity confirmed. GMP docs seamless for our FDA sub."
Tom K., Ops Mgr., Florida: "High-speed air ship cut lead time 50%. Top service!"
Emily W., Purchasing Lead, New York: "OEM customization perfect for our vet line. Recommend!"
Urgent: 10% off first order. Free 1kg sample. 100% money-back guarantee.
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