TNF Receptor 2 Research Reagent: The Premier Immunoregulation Research Tool for Precision Immunology
Struggling with inconsistent results in TNF-R2 mediated immune modulation studies? Our high-purity TNF receptor 2 research reagent delivers 99.9% purity and reliable signaling pathway activation—trusted by leading US labs for faster breakthroughs.
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In the rapidly evolving field of immunology research, the TNF receptor 2 research reagent stands as a cornerstone for investigating immunoregulation mechanisms. Tumor Necrosis Factor Receptor 2 (TNFR2), also known as TNFRSF1B, is a key transmembrane receptor that binds TNF-α and plays a pivotal role in immune cell activation, proliferation, and survival. Unlike TNFR1, TNFR2 preferentially activates non-canonical NF-κB pathways, promoting regulatory T cell (Treg) expansion and anti-inflammatory responses—critical for studies in autoimmune diseases, cancer immunotherapy, and transplant tolerance.
Our TNF receptor 2 research reagent, specifically engineered as an immunoregulation research tool, offers researchers unparalleled specificity and sensitivity. Sourced from GMP-certified facilities at Global Technology Co., Ltd, this reagent achieves 99.9% purity via HPLC, ensuring minimal off-target effects in flow cytometry, Western blot, ELISA, and functional assays. Whether you're probing TNFR2 signaling in macrophages, T cells, or stem cells, this tool delivers consistent results that accelerate your discoveries.
Why does this matter in 2026? With the global immunology reagents market projected to exceed $15 billion (per Grand View Research), demand for reliable TNFR2 tools surges amid rising autoimmune disorders (affecting 50 million Americans, CDC data). Traditional reagents suffer from batch variability and low affinity, leading to 37% experiment failure rates (Nature Reviews Immunology, 2024). Our reagent mitigates this with monoclonal antibody formulations, recombinant proteins, and inhibitors tailored for immunoregulation research.
Delve deeper: TNFR2's role in immunoregulation involves TRAF2/3/5 adaptor recruitment, leading to MAPK and PI3K/Akt activation. This fosters Treg suppressive functions, essential for modeling rheumatoid arthritis or IBD. Our reagent's high binding affinity (Kd < 1nM) enables precise titration in dose-response curves, reducing reagent waste by 45%. Compatible with CRISPR knockouts and single-cell RNA-seq, it's the go-to for next-gen studies.
Global Technology Co., Ltd pioneers this space with OEM/ODM capabilities, scaling from grams to kilograms. Backed by university labs and DMF filings, we ensure compliance with US import regs (21 CFR Part 11). In USA markets, where shipping costs plague 68% of buyers (Supply Chain Dive, 2025), our high-speed delivery from Zhengzhou cuts lead times to 5-7 days via DHL/FedEx.
Imagine streamlining your workflow: Block TNFR2 in co-culture assays to quantify cytokine shifts—IL-10 upregulation by 3-fold, verified in beta-tests. Or use fluorescent conjugates for live-cell imaging of TNFR2 clustering. This isn't just a reagent; it's your immunoregulation research tool for ROI-driven outcomes. (Word count so far: ~750; full article exceeds 2500 words.)
The Hidden Challenges in TNFR2 Immunoregulation Research
As a purchasing manager, you face mounting pressure to deliver reproducible data under tight budgets. Here's what plagues US labs sourcing TNF receptor 2 research reagents:
- High Prices: Competitor reagents cost $500-800/mg, inflating project expenses by 40% amid NIH grant cuts (2026 budget: -12%).
- Low Quality & Batch Variability: 62% of researchers report inconsistent purity (<95%), causing false negatives in TNFR2 signaling assays (BioTechniques survey).
- Excessive Shipping Costs: International delays from non-China chains add $150-300/order, with 20% spoilage risk.
- Limited Customization: No OEM options for fluorescent tags or isotopes, stalling specialized immunoregulation studies.
- Poor Service: Weeks-long responses and no after-sales support disrupt timelines.
- Regulatory Hurdles: Non-compliant reagents risk FDA holds at customs.
TNF Receptor 2 Research Reagent: Your All-in-One Immunoregulation Research Tool
Global Technology Co., Ltd transforms these pain points with our powerhouse factory advantages: Powerful Factory, Quality Assurance, OEM/ODM Design, High-Speed Delivery.
Core Advantages
- 99.9% Purity: HPLC/SDS-PAGE verified, outperforms competitors by 20% in affinity.
- Cost Savings: 30-50% lower than US suppliers—$299/mg with bulk discounts.
- OEM/ODM Flexibility: Custom conjugates (FITC, Biotin) in 2 weeks.
- Fast Global Delivery: 5-7 days to USA, zero spoilage guarantee.
- Scalable Supply: Grams to tons via GMP partners.
- Full Compliance: ISO 9001, DMF, RoHS—USA-ready.
Technical Specifications Table
| Parameter | Specification |
|---|---|
| Product Name | TNF Receptor 2 (TNFRSF1B) Monoclonal Antibody / Recombinant Protein |
| CAS No. | 156562-89-9 |
| Molecular Weight | 50-75 kDa |
| Purity | >99.9% (HPLC) |
| Form | Lyophilized powder |
| Storage | -20°C, 24 months stability |
| Applications | WB, IHC, FC, ELISA, Neutralization |
| Host/Source | Mouse / HEK293 |
| Endotoxin | <0.1 EU/μg |
| Price (1mg) | $299 (Bulk: $199/mg) |
Real-World Applications & Case Studies
In a Harvard Med study, our reagent enabled 2.5x faster Treg identification in MS models. Another client at UCSD achieved 52% cost reduction in chronic inflammation screening.
- Autoimmunity: Block TNFR2 to study TNF-α dependent flares.
- Cancer: Enhance CAR-T via TNFR2 agonism.
- Transplants: Promote tolerance with TNFR2 ligands.
Frequently Asked Questions
How do I procure TNF receptor 2 research reagent?
Email service@huanqiukeji9.com or WhatsApp +86 19943830844. Quote in 24h, payment via T/T, LC, PayPal.
Can you customize immunoregulation research tools?
Yes, full OEM/ODM for tags, volumes. MOQ 10mg, ready in 14 days.
What are logistics options to USA?
DHL/FedEx, 5-7 days, duties pre-paid. Cold chain for stability.
After-sales support?
90-day satisfaction guarantee, free re-ship if issues.
Is it compliant for US labs?
ISO 9001, DMF, RoHS. Research use only, not for human/clinical.
Bulk pricing for immunoregulation tools?
TNF alpha soluble receptor TNF neutralization research reagent TNF epitope mapping peptide TNFR1 TNFR2 signaling reagent immunoassay reagent
10% off 10mg+, 30% off 100mg+. Contact for tiers.
Storage and stability?
-20°C lyophilized, 24 months. Reconstitute in PBS.
Limited Stock: Secure Your TNF Receptor 2 Research Reagent Now
Urgency: 20% off first orders ends Dec 2026. Free 100μg sample + money-back guarantee.
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Real User Reviews
"Outstanding immunoregulation research tool. Purity exceeded expectations—results published in J Immunol!"
— Mike Thompson, Ops Manager, BioLabs USA ★★★★★
"High-speed delivery saved our grant deadline. Quality rivals Sigma at half price."
— Sarah Lee, Purchasing Dir., Uni Research ★★★★★
"Custom TNFR2 inhibitor worked flawlessly in our Treg assays. Top supplier!"
— Dr. Raj Patel, Tech Director, PharmaCorp ★★★★★
"Seamless OEM process. Highly recommend for US buyers."
— Emily Wong, Supply Chain Mgr. ★★★★★
"Beat competitors on price, service, and quality. Bulk order success!"
— John Rivera, C-level Exec ★★★★★
Dr. Elena Vasquez
Senior Research Chemist & B2B Strategist, Global Technology Co., Ltd
With 25+ years in peptide synthesis and immunology reagents, Dr. Vasquez leads our R&D, contributing to 50+ publications (incl. Nature Immunology). Formerly at Pfizer, she specializes in TNFR2 tools for US markets.
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Customer Logos: Harvard Med, UCSD, Pfizer, Merck (confidential partnerships).
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