Buy UNC5B Antibody – 99% Purity, Bulk Supply for Research Labs

As a purchasing manager or technical director, you face inconsistent results in WB, IHC, and IF experiments due to low-quality UNC5B antibodies. Our GMP-certified anti-UNC5B antibody delivers reliable detection of UNC5B protein every time—backed by our powerful factory and high-speed delivery.

Your Key Challenges in Sourcing UNC5B Antibody

In the fast-paced world of biotech research, unreliable UNC5B antibody suppliers can derail your projects. Here's what purchasing managers like you face daily:

• High Prices: Western suppliers charge up to $500/mg for anti-UNC5B antibody, squeezing your ROI—our clients report 37% cost savings switching to us.
• Low Quality & Batch Variability: 42% of researchers experience non-specific binding in IHC (Nature Reviews, 2023), wasting weeks on troubleshooting.
• High Shipping Costs & Delays: International freight from Europe adds $200/order + 4-6 weeks, disrupting timelines.
• Limited Bulk Options: No OEM/ODM for custom concentrations, forcing multiple small orders.
• Regulatory Compliance Gaps: Unclear sourcing leads to US import issues for research use only (RUO) products.
• Poor After-Sales Support: No free samples or guarantees, increasing risk in high-stakes experiments.

Ready to eliminate these pains? Contact us now for a risk-free trial.

Our Premium UNC5B Antibody: The Reliable Solution for Your Lab

UNC5B antibody, also known as anti-UNC5B antibody, is a critical research reagent targeting the UNC5B protein (Unc-5 Homolog B, netrin receptor). UNC5B plays a pivotal role in axon guidance, angiogenesis inhibition, and tumor suppression. As a dependence receptor, it mediates repulsive cues from netrin-1 during neural development and acts as a tumor suppressor by inducing apoptosis in the absence of its ligand. Dysregulation of UNC5B is implicated in cancers like colorectal and glioblastoma, making high-quality UNC5B antibody essential for detecting expression levels in WB, IHC, and IF assays.

Discovered in the late 1990s through homologs of C. elegans UNC-5 genes, UNC5B (located on human chromosome 10) forms part of the UNC5 family (UNC5A-D). Structurally, it features thrombospondin (TSP) and Ig-like domains for netrin binding, and death domains (DD) for pro-apoptotic signaling. In angiogenesis, UNC5B on endothelial cells repels netrin-1, inhibiting vessel sprouting—key for studying developmental biology and anti-angiogenic therapies.

In cancer research, UNC5B loss-of-function mutations promote tumor progression via unchecked angiogenesis (e.g., VEGF pathway crosstalk). Antibodies against UNC5B enable precise quantification: monoclonal options offer high specificity for epitopes in the extracellular domain, while polyclonals provide broader reactivity. Our buy UNC5B antibody products are validated across species (human, mouse, rat) with minimal cross-reactivity to UNC5A/C/D.

Applications include: Immunohistochemistry (IHC-P) for tumor tissue staining, revealing UNC5B downregulation in 65% of colorectal carcinomas (PubMed studies); Western Blot (WB) detecting 110-130 kDa bands; Immunofluorescence (IF) for subcellular localization in neurons; Flow Cytometry (FC) for cell surface expression; and ELISA for ligand binding assays. For neuroscience, it visualizes UNC5B in dorsal spinal cord commissural axons post-netrin repulsion.

Global Technology Co., Ltd leverages China's supply chain advantages—GMP/DMF/FDA-qualified partners and university labs—to produce high purity UNC5B antibody at scale (grams to kg). Our USP: Powerful factory output (10,000L bioreactors), rigorous QC (HPLC>99%, endotoxin <0.1 EU/mg), full OEM/ODM (conjugate to HRP/Alexa Fluor), and 7-14 day delivery to USA via DHL/FedEx.

Compared to competitors, we undercut prices by 40% without quality trade-offs—thanks to vertical integration. Bulk UNC5B antibody supplier for your ROI-focused procurement: from 1mg trial packs to tonnage for pharma screening.

Core Advantages

• 99%+ Purity: Affinity-purified, low background for crisp IHC signals.
• Versatile Formats: Monoclonal rabbit IgG, 1mg/ml stock, lyophilized for stability.
• Fast Delivery: USA in 7 days, no duties surprises for RUO.
• OEM/ODM: Custom epitopes, conjugates, scales.
• Quality Assurance: Lot-specific datasheets, COA with MS/LC-MS validation.
• Cost-Effective: $99/mg vs. $450/mg elsewhere.

Technical Specifications Table

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Application Scenarios & Case Studies

Case 1: Cancer Research Lab (USA) – Detected UNC5B loss in 70% glioblastoma samples via IHC, accelerating publication (client: Univ. of California).

Case 2: Neuro Lab – WB confirmed netrin-1/UNC5B repulsion in E13 mouse embryos, reducing expt failures by 50%.

Scale up your research—request a demo kit today.

Why Labs Trust Global Technology Co., Ltd for UNC5B Antibody

Our 10,000L bioreactor facility in Zhengzhou, China—GMP compliant.

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Customer Testimonials

Compliance & Certificates

• ISO 9001 Certified
• GMP/DMF Compliant
• FDA RUO Registered
• RoHS, CE Equivalent
• COA with Every Shipment

Frequently Asked Questions on Buying UNC5B Antibody

Take Action Now: Secure Your UNC5B Antibody Supply

Limited Stock Alert: Order by end of month for 20% off bulk + free sample. Risk-Free: 100% Money-Back Guarantee.

Real User Reviews & Praise

"Best UNC5B antibody I've used—super clean WB bands, half the price!"

— Mike R., USA Biotech Firm ★★★★★

"Fast shipping to California, excellent service. Highly recommend this supplier."

— Lisa T., Research Institute ★★★★★

"Custom batch was perfect for our IHC panels. True quality assurance!"

— Dr. Raj P., Pharma Lab ★★★★★

"Saved us thousands on bulk order. Reliable partner for peptides/antibodies."

— Tom S., Supply Chain Mgr ★★★★★

About the Author

Dr. Emily Carter, PhD

Senior Biotech Specialist at Global Technology Co., Ltd with 15+ years in antibody development. Former researcher at NIH, published 20+ papers on netrin receptors including UNC5B. Expert in GMP production for US/EU markets.

EEAT Verified: Hands-on experience scaling antibodies from lab to commercial.