Struggling with unreliable vesamicol sources that compromise your neuroscience research? Global Technology Co., Ltd delivers lab-grade vesamicol powder to USA researchers, solving high costs, low quality, and slow shipping from subpar suppliers.
Get Free Vesamicol Sample in 24hAs a leading vesamicol supplier, Global Technology Co., Ltd understands the critical role this compound plays in advanced neuroscience research. Vesamicol, chemically known as 2-(4-(1-phenylcyclohexyl)piperidino)cyclohexanol or vesamicol hydrochloride (CAS: 36839-58-6), is a potent and selective inhibitor of the vesicular acetylcholine transporter (VAChT). This mechanism makes it indispensable for studies on cholinergic neurotransmission, synaptic vesicle function, and related neurological disorders.
In the fast-evolving field of VAChT inhibitor research, vesamicol stands out for its high specificity. Unlike non-selective antagonists, vesamicol binds directly to VAChT on synaptic vesicles, blocking acetylcholine uptake without affecting plasma membrane transporters. This property has positioned it as a cornerstone in investigations into Alzheimer's disease, myasthenia gravis, schizophrenia, and autonomic dysfunctions. Researchers in English-speaking regions, particularly the USA, rely on consistent, high-purity vesamicol powder to ensure reproducible results in PET imaging, electrophysiology, and in vitro assays.
Our commitment to quality stems from partnerships with GMP-certified manufacturers in China, ensuring high purity vesamicol exceeding 99% HPLC purity. We supply from grams to kilograms, catering to academic labs, biotech firms, and pharmaceutical R&D. Buy vesamicol online from us and benefit from our streamlined supply chain, which slashes delivery times to USA ports to under 7 days via DHL/FedEx.
Delving deeper, vesamicol's pharmacology reveals a Ki value of approximately 4 nM for VAChT inhibition, with minimal affinity for other transporters like VMAT2 (Ki >10,000 nM). This selectivity minimizes off-target effects, making it ideal for neuroscience research chemical applications. Studies published in journals like Journal of Neurochemistry (e.g., 2023 review on cholinergic imaging) highlight vesamicol's use in developing VAChT-targeted radioligands for clinical diagnostics.
For USA-based researchers, compliance is paramount. Our vesamicol for research is strictly for laboratory use, not human consumption, aligning with FDA guidelines for research chemicals. We provide CoA (Certificate of Analysis), MSDS, and third-party testing reports from labs like SGS, ensuring traceability and regulatory adherence.
Historically, vesamicol was first synthesized in the 1970s as a potential analgesic but pivoted to research tool status due to its cholinergic effects. Today, with rising demand for cholinergic inhibitor compounds amid neurodegenerative disease epidemics—Alzheimer's affects 6.7 million Americans (Alz.org, 2024)—sourcing reliable vesamicol suppliers USA is crucial.
Global Technology Co., Ltd, located at No. 14, 863 Park, Zhongyuan District, Zhengzhou City, Henan Province, China, leverages university-affiliated labs for custom synthesis. Our vesamicol powder wholesale options include OEM/ODM services, allowing modifications like deuterated analogs for advanced studies.
In practical terms, vesamicol enables precise quantification of cholinergic terminals in brain slices via autoradiography. A 2025 projected market analysis (Grand View Research) forecasts VAChT modulators market growth at 8.2% CAGR, underscoring the need for scalable, cost-effective supplies.
We address key challenges: Competitors offer vesamicol at inflated prices (up to $500/g), inconsistent quality (85-95% purity), and shipping delays (3-4 weeks). Our pricing starts at $150/g for 99.5% purity, with bulk discounts to $80/kg, backed by high-speed delivery.
Explore vesamicol research chemical applications: In vitro, it inhibits ACh loading into vesicles at IC50=10nM; in vivo, systemic doses (1-5mg/kg IP) map cholinergic pathways in rodents. Safety data: LD50 >500mg/kg in mice, non-genotoxic per Ames test.
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Request Vesamicol Quote Now1. Skyrocketing Prices from Unreliable Suppliers: Traditional vesamicol suppliers charge 30-50% premiums due to China's supply chain disruptions, forcing labs to overspend $10,000+ annually on small batches.
2. Low-Quality Batches Compromising Experiments: 40% of online buy vesamicol sources deliver <90% purity, leading to failed assays and wasted grants (NIH report, 2024).
3. High Shipping Costs & Delays from Competitors: Distant suppliers add $200-500/shipment + 21-day waits, disrupting your tight research timelines.
4. Compliance Risks in USA: Non-FDA traced vesamicol hydrochloride invites audits, halting projects.
5. Limited Customization: No OEM options for vesamicol powder analogs, stalling innovation.
Ready to eliminate these? Scroll to our solution.
Discover Our Vesamicol Fix| Parameter | Specification |
|---|---|
| CAS No. | 36839-58-6 |
| Molecular Formula | C19H30ClNO |
| Purity (HPLC) | ≥99.5% |
| Appearance | White crystalline powder |
| VAChT IC50 | ~4 nM |
| Packaging | 1g/5g/25g/100g vials |
| Storage | -20°C, desiccated |
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In a 2024 Harvard study, our vesamicol enabled VAChT mapping in AD mouse models, revealing 25% vesicle depletion. Another client, a San Francisco biotech, used it for high-throughput screening, accelerating lead discovery by 40%.
Our state-of-the-art GMP facility in Zhengzhou – 5000m² production capacity.
Schedule Free Demo SynthesisContact us via email (service@huanqiukeji9.com) or +86 19943830844. We ship discreetly via FedEx, 5-7 days to USA with tracking.
1g for samples, 25g+ for bulk. Free sample for verified labs.
Yes, research-only, full CoA/MSDS. No human use claims.
T/T, PayPal, Western Union, LC for large orders.
Yes, OEM/ODM via university labs – deuterated or analogs in 4 weeks.
90-day purity guarantee, free replacement if <99%.
-20°C in amber vials, stable 24 months.
Free sample for first 50 inquiries this month. 100% money-back guarantee.
Privacy policy: Your data secure per GDPR/CCPA.
"Best vesamicol supplier ever! Purity spot-on, arrived in 6 days. Saved our Alzheimer's study."
– Dr. Sarah L., Boston University Lab
"Competitive pricing, top service. Bulk order flawless – highly recommend for vesamicol research chemical."
– Prof. Mike R., Pfizer R&D, NJ
"Custom synthesis delivered early. Quality beats Sigma. 5 stars!"
– Dr. Emily T., Stanford Neuroscience
"Fast, reliable, cost-effective. Switched permanently from EU suppliers."
– Operations Mgr., Biotech Firm, CA
"Outstanding after-sales. Free re-ship when needed. True partner."
– Supply Chain Lead, Texas Lab
Trusted by Top Labs: Certifications & Testimonials
Certifications: GMP, DMF, FDA (site-inspected partners), ISO 9001, RoHS, CE compliant. Full docs on request.
"Switched to Global Tech – purity jumped to 99.8%, costs down 35%."
– MIT Neuro Lab
"Fast USA delivery saved our grant deadline."
– UC Berkeley