β- Amyloid (1-34) CAS NO.186359-65-9

β- Amyloid (1-34) CAS NO.186359-65-9

β- Amyloid (1-34) CAS NO.186359-65-9

β- Amyloid (1-34) CAS NO.186359-65-9

β- Amyloid (1-34) CAS NO.186359-65-9

β-Amyloid (1-34) is a synthetic peptide fragment representing the N-terminal region of the full-length β-amyloid protein, which is critically involved in the pathogenesis of Alzheimer’s disease. This peptide is widely used in neuroscience research to study amyloid aggregation, neurotoxicity, and early-stage plaque formation, offering researchers a valuable tool to investigate disease mechanisms and potential therapeutic targets in both academic and pharmaceutical settings.


TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
β-Amyloid (1-34)
CAS NO.
186359-65-9
Appearance
White to off-white lyophilized powder
Molecular Formula
C₁₇₀H₂₅₃N₄₇O₅₂
Molecular Weight
3787.2 g/mol
Amino Acid Sequence
Not provided (per request)
Purity (RP-HPLC)
≥98.0%
Solubility
Soluble in 1M acetic acid, DMSO, or deionized water
Endotoxin
< 1 EU/mg
Biological Activity
Promotes neuronal apoptosis; involved in amyloid plaque formation; used for Alzheimer’s disease research
Storage Conditions
Store at -20°C, protected from light and moisture
Stock Location
USA / Germany / China (optional, based on actual stock)
MOQ
1 mg


1.Mechanism of Action

β-Amyloid (1-34) exerts its biological effects by adopting conformations that facilitate oligomerization and fibrillization, leading to the formation of toxic aggregates that disrupt neuronal membrane integrity, induce oxidative stress, and trigger inflammatory responses. It also interferes with synaptic signaling and promotes apoptotic pathways in neuronal cells, mimicking the early events in Alzheimer’s pathology and serving as a reliable model for studying disease progression at the molecular level.

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2.Product Indications

This peptide is primarily indicated for use in in vitro and in vivo research focused on neurodegenerative diseases, particularly Alzheimer’s disease. It is suitable for applications including amyloid aggregation studies, neurotoxicity assays, drug screening for anti-amyloid compounds, and development of diagnostic tools targeting early amyloid deposition. Researchers in academia, biotech, and pharmaceutical industries will find it indispensable for advancing understanding of neurodegeneration mechanisms.

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3.Clinical Efficacy of Product

While not intended for clinical use, β-Amyloid (1-34) has demonstrated high efficacy in preclinical models as a benchmark for evaluating the impact of potential therapeutics on amyloid-induced neurodegeneration. Its consistent aggregation properties and reproducible neurotoxic profile make it an essential reagent for validating drug candidates aimed at reducing amyloid burden, improving synaptic function, or delaying disease onset in experimental models.

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4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.


Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.


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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


HotTags:Amyloid, #Alzheimers, #Neuroscience, #Peptide, #ResearchChemical, #Neurotoxicity, #DrugDiscovery, #BetaAmyloid, #LabReagent, #Neurodegeneration, #PreclinicalResearch, #amyloidplaque

If you have any product requirements, please send an email to:business@huanqiukeji9.com;whatsapp:85270846510

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