Name: All Trans-Retinal: Pure Vision Enhancement Formula
Availability: InStock
Rating: 4.5 (89 reviews)

All Trans-Retinal CAS NO.116-31-4

All Trans-Retinal, also known as Retinaldehyde or Vitamin A aldehyde, is a high-purity yellow crystalline powder primarily supplied for advanced cosmetic formulation, vision science research, and biochemical studies. As a direct metabolic precursor to retinoic acid, it occupies a critical position in the vitamin A metabolic pathway, offering formulators a potent yet relatively low-irritation alternative to traditional retinoids like tretinoin. This versatile compound is specifically targeted at skincare brands developing next-generation anti-aging and anti-acne products, as well as vision researchers and optogenetics scientists who require a reliable chromophore or biochemical reagent to study phototransduction cycles and neural circuit manipulation in controlled laboratory environments.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	All Trans-Retinal
CAS NO.	116-31-4
Appearance	Bright yellow crystalline powder
Molecular Formula	C20H28O
Molecular Weight	284.44 g/mol
Purity (RP-HPLC)	≥98%
Solubility	Soluble in DMSO, chloroform, absolute alcohol; slightly soluble in oil
Endotoxin	≤10 EU/mg
Biological Activity	Activates retinoic acid receptors (RAR/RXR); Regulates epidermal cell differentiation and proliferation
Storage Conditions	-20°C, protected from light, dry and sealed
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

The biological activity of All Trans-Retinal is defined by its rapid single-step enzymatic conversion into retinoic acid directly within the epidermis, where it then binds to nuclear retinoic acid receptors (RARs and RXRs) to modulate gene expression responsible for cell turnover, collagen synthesis, and keratinocyte differentiation. In dermatological applications, this mechanism accelerates the shedding of dead skin cells and boosts dermal matrix production while maintaining a favorable irritation profile due to the skin’s regulated, rate-limited conversion process. Simultaneously, in ocular and neurological research, the molecule functions as a vital chromophore that undergoes light-induced isomerization to trigger G-protein signaling cascades in visual pigments, or serves as a cofactor in optogenetic tools to enable precise light-controlled activation of engineered ion channels in neuronal studies.

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2.PRODUCT INDICATIONS

This product is indicated for use by professional cosmetic chemists, private label skincare manufacturers, and biochemical research laboratories engaged in dermatological product development or cellular biology studies. It is ideally suited for formulators creating high-performance serums, creams, and lotions aimed at reducing fine lines, hyperpigmentation, and acne breakouts, typically incorporated at concentrations ranging from 0.05% to 0.15% in stabilized, anhydrous bases. Additionally, it serves as an essential analytical reference standard for quantifying vitamin A metabolites and as a specialized reagent for academic and pharmaceutical researchers investigating retinal degeneration, visual cycle biochemistry, and the development of light-sensitive proteins for advanced neuromodulation therapies.

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3.CLINICAL EFFICACY OF PRODUCT

While All Trans-Retinal is marketed as a raw cosmetic active ingredient and research chemical rather than a finished clinical drug, its efficacy is well-supported by comparative dermatological studies showing it works up to 11 times faster than retinol in improving skin texture and reducing photoaging signs due to its proximity to active retinoic acid. Clinical observations confirm that topical formulations containing retinaldehyde significantly increase epidermal thickness, stimulate collagen types I and III, and reduce acne lesions with notably better tolerability and less erythema than prescription retinoic acid, making it suitable for sensitive skin applications. These validated performance outcomes, combined with its established role in the visual cycle, make it a high-value ingredient for brands seeking clinically inspired, consumer-friendly anti-aging solutions without the regulatory constraints of prescription-strength vitamin A analogs.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

Hot Tags: All Trans-Retinal, Retinaldehyde, Vitamin A aldehyde, Retinene, Retinal, Anti-aging active ingredient, Retinoid, Visual chromophore, Cosmetic raw material, Skincare supplier.

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