Name: HGH 176-191: Burn Fat and Enhance Your Physique
Availability: InStock
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HGH 176-191 CAS NO.66004-57-7

Peptide Fragment 176-191—also known as hGH Fragment 176-191, tyr-hGH 177-191, or AOD-9604—is believed by researchers to potentially promote weight loss and fat burning in a manner similar to that of human growth hormone (hGH). Growth hormone is a protein hormone composed of approximately 190 amino acids, synthesized and secreted by the somatotrophs of the anterior pituitary gland. It plays a crucial role in regulating a variety of complex physiological processes, including growth and metabolism. As a therapeutic agent, growth hormone holds significant value in both human and veterinary medicine.hGH is a naturally occurring hormone which, as its name implies, not only stimulates growth but also promotes the catabolism of adipose tissue and facilitates the release of lipids from fat cells. Peptide Fragment 176-191 constitutes a small "fragment" of the hGH molecule, comprising 16 amino acids. It encompasses the final 16 amino acids of the hGH molecule and is regarded by scientists as the "lipolytic fragment" of hGH. The term "lipolytic" reflects the molecule's purported fat-burning properties. To enhance the peptide's stability, the first amino acid in the hGH Fragment 176-191 sequence has been replaced with tyrosine; consequently, the peptide is also designated as Fragment tyr-hGH 177-191.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	HGH 176-191 (Human Growth Hormone Fragment 176-191)
CAS NO.	66004-57-7
Appearance	White to off-white crystalline powder
Molecular Formula	C₇₈H₁₂₃N₂₃O₂₂S₂
Molecular Weight	1799.1 g/mol
Purity (RP-HPLC)	≥ 98.0%
Solubility	Soluble in water and dilute acids; partially soluble in DMSO; insoluble in non-polar solvents
Endotoxin	≤ 50 EU/mg (for cell culture and in vitro use; may differ by batch)
Biological Activity	Selective growth hormone receptor agonist; mimics lipolytic effects of HGH without stimulating IGF-1; promotes fat metabolism and lean body mass maintenance
Storage Conditions	Lyophilized powder: Store at 2–8°C in a dry, dark place; stable for 24–36 months. Reconstituted solutions: Store at -20°C, protected from light, and use within 1–2 weeks; avoid freeze-thaw cycles
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

HGH 176-191 functions as a selective agonist of the growth hormone receptor, binding to and activating signaling pathways that enhance lipolysis (breakdown of stored fat) and suppress lipogenesis (fat synthesis) in adipose tissue. Unlike full-length HGH, it does not significantly stimulate insulin-like growth factor 1 (IGF-1) production, reducing risks of hyperplasia and organomegaly. This targeted mechanism allows researchers to isolate and study the direct metabolic effects of GH on fat mobilization and energy homeostasis.

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2.PRODUCT INDICATIONS

Intended for research use only, HGH 176-191 is suitable for investigating metabolic disorders including obesity, type 2 diabetes, and age-related muscle loss. It supports studies on adipose tissue remodeling, energy expenditure, and the role of GH in lipid metabolism. The peptide is also valuable for preclinical models exploring therapeutic strategies for weight management and lean mass retention without the complications of systemic GH excess.

3.CLINICAL EFFICACY OF PRODUCT

Growth hormone is indicated for the treatment of growth failure in pediatric patients caused by endogenous growth hormone deficiency, including Turner syndrome, Prader-Willi syndrome (PWS), Idiopathic Short Stature (ISS), short stature or growth failure associated with SHOX gene deficiency, and children born Small for Gestational Age (SGA). It is also indicated for the treatment of growth failure in children with chronic kidney disease, up until the time of renal transplantation. Furthermore, it is indicated for the treatment of adult-onset growth hormone deficiency—whether or not associated with multiple hormone deficiencies (hypopituitarism)—arising from pituitary disease, hypothalamic disease, surgery, radiation therapy, or trauma. It is also used to treat adult-onset growth hormone deficiency of congenital, genetic, acquired, or idiopathic etiology.

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4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

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