Name: PT141 Peptide for Boosting Libido & Natural Sexual Wellness
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PT141 CAS NO. 189691-06-3

PT141, also known by its CAS number 189691 – 06 – 3, is a synthetic peptide with a molecular formula of C₅₂H₇₃N₁₃O₁₁ and a molecular weight of 1057.23 g/mol. This compound acts as a selective agonist of the melanocortin – 4 receptor (MC4R), playing a crucial role in regulating sexual arousal and central nervous system pathways. Unlike traditional PDE5 inhibitors, PT141 exerts its effects centrally in the brain, enhancing dopaminergic and melanocortin signaling to increase sexual desire and arousal in both men and women. It presents a novel approach for treating hypoactive sexual desire disorder (HSDD) and shows potential in various sexual health applications, including enhancing sexual arousal and libido in patients unresponsive to first – line therapies, and as an adjunctive therapy for psychogenic erectile dysfunction and female sexual interest/arousal disorder. With its unique mechanism of action and promising therapeutic prospects, PT141 is a significant product in the field of sexual health research and treatment.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	PT141
CAS NO.	189691 – 06 – 3
Appearance	White to off-white lyophilized powder
Molecular Formula	C₅₂H₇₃N₁₃O₁₁
Molecular Weight	1057.23 g/mol
Amino Acid Sequence	Ac – Nle – Asp – His – D – Phe – Arg – Trp – Gly – Lys – Pro – Val – NH2
Purity (RP-HPLC)	≥ 98.0%
Solubility	Soluble in water and some organic solvents (such as DMSO, etc.)
Endotoxin	< 1.0 EU/mg
Biological Activity	Verified through in vivo and in vitro experiments, it has significant biological activity. In animal models, it can effectively regulate specific physiological functions.
Storage Conditions	Store at -20°C, protected from light, and keep dry. Avoid repeated freezing and thawing.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

PT-141 (Bremelanotide) is a synthetic melanocortin receptor agonist that selectively activates MC4R in the central nervous system, enhancing dopaminergic and melanocortin signaling to increase sexual desire and arousal in both genders. Unlike PDE5 inhibitors, it acts centrally in the brain, bypassing the need for physical stimulation. Administered via subcutaneous injection, effects appear within 30–60 minutes.

2.PRODUCT INDICATIONS

Primary Target: Treatment of hypoactive sexual desire disorder (HSDD) in premenopausal women and men.

Sexual Health: Adjunctive therapy for psychogenic erectile dysfunction and female sexual interest/arousal disorder; investigational use in antidepressant-associated dysfunction.

Research: Studies on melanocortin receptor pharmacology, arousal pathways, and comparative efficacy with PDE5 inhibitors.

3.CLINICAL EFFICACY OF PRODUCT

Libido & Arousal: Trials show significant increases in desire scores and satisfying sexual events in women with HSDD (up to 1.2–1.8× baseline over 8 weeks); men report improved arousal/satisfaction.

Onset: Effects begin 30–60 minutes post-injection, lasting 6–72 hours depending on dose.

Safety: Generally well-tolerated; common adverse events include nausea, flushing, headache, injection-site reactions (transient/dose-dependent); contraindicated in uncontrolled hypertension or cardiovascular history.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.