Glutathione CAS NO.70-18-8

Glutathione CAS NO.70-18-8

Glutathione CAS NO.70-18-8

Glutathione CAS NO.70-18-8

Glutathione CAS NO.70-18-8

Glutathione is a naturally occurring tripeptide antioxidant composed of glutamic acid, cysteine, and glycine, existing in reduced (GSH) and oxidized (GSSG) forms. It is the body's primary endogenous antioxidant and a master regulator of cellular redox balance. Glutathione is essential for detoxification, immune function, and the protection of cells from oxidative stress. It is widely used in pharmaceuticals, nutraceuticals, cosmetics, and research applications.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Glutathione
CAS NO.
70-18-8
Appearance
White to off-white lyophilized powder
Molecular Formula
C10H17N3O6
Molecular Weight
307.32 g/mol
Purity (RP-HPLC)
≥98%
Solubility

Freely soluble in water (≥100 mg/mL); slightly soluble in ethanol, insoluble in ether and chloroform

Endotoxin< 1.0 EU/mg
Biological Activity
Potent intracellular antioxidant, scavenges free radicals; supports skin whitening by inhibiting tyrosinase activity and melanin synthesis; replenishes cellular redox balance, protects skin from oxidative stress and photoaging; promotes detoxification.
Storage Conditions
Store at 2–8°C in a dry, dark, sealed container; avoid high temperature and direct light; stable for 24 months under recommended storage.
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

Glutathione functions through multiple critical biochemical pathways:
  1. Direct Antioxidant Activity: The sulfhydryl (-SH) group in its reduced form (GSH) directly neutralizes reactive oxygen species (ROS) such as free radicals, peroxides, and lipid peroxides.

  2. Enzyme Cofactor: Serves as an essential cofactor for antioxidant enzymes, primarily Glutathione Peroxidase (GPx), which reduces hydrogen peroxide and lipid hydroperoxides to water and alcohol, and Glutathione S-Transferase (GST), which conjugates GSH to toxins for excretion.

  3. Regeneration of Other Antioxidants: It regenerates other vital antioxidants like vitamins C and E back to their active states.

  4. Detoxification & Metal Chelation: Conjugates with xenobiotics, heavy metals, and other toxins in Phase II detoxification, facilitating their removal. It also chelates certain metal ions.

  5. Immune System Modulation: Supports optimal lymphocyte function and cytokine production.

2.PRODUCT INDICATIONS

Glutathione is indicated for a vast range of applications:

  • Pharmaceuticals & Clinical Use: Used in treatments for acetaminophen overdose, to mitigate chemotherapy side effects, and in managing certain neurodegenerative, hepatic, and pulmonary conditions.

  • Nutraceuticals & Dietary Supplements: Promoted for liver support, immune boosting, anti-aging, detoxification, and improving skin brightness.

  • Cosmetics & Skincare: A key ingredient in skin-lightening/whitening products (inhibits tyrosinase), anti-aging serums (fights oxidative stress), and brightening treatments.

  • Research Biochemical: Fundamental in studies on oxidative stress, aging, mitochondrial function, apoptosis, and disease mechanisms.

  • Functional Foods & Beverages: Added to products for health and wellness benefits.

3.CLINICAL EFFICACY OF PRODUCT

Extensive clinical research supports the efficacy of glutathione:
  • Detoxification & Liver Health: Proven antidote for acetaminophen poisoning. Effective in improving liver function markers in conditions like NAFLD.

  • Antioxidant Defense: Clinically shown to reduce markers of oxidative stress in various diseases and in aging populations.

  • Skin Lightening: Multiple studies demonstrate that oral, intravenous, or topical glutathione can lead to a measurable reduction in skin melanin index, promoting skin lightening.

  • Immune Support: Supplementation can improve lymphocyte response and reduce inflammation.

  • Mitigation of Chemo Side Effects: Helps protect healthy cells from oxidative damage during chemotherapy.

Its therapeutic potential is dose- and delivery-dependent, with intravenous and liposomal forms often showing higher bioavailability.


    4.Certificate

    • GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

    Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


    We prioritize:

    1.A rigorous quality management system

    2.Batch traceability and stability data

    3.Professional laboratory testing and validation

    4.Compliance with international trade standards


    Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

    5.DELIVERY & SHIPPING

    We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

    Professional and Secure Packaging

    Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

    We can also customize packaging according to customer needs.

    Shipping Methods 

    Main Method: International Air Freight

    We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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    Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

    We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


    Hot Tags: Pentapeptide-25, Anti-aging peptide, Collagen booster, Skin firming, Wrinkle reducer, Cosmetic ingredient, Peptide synthesis, Skincare, CAS 1000313-64-36, Synthetic peptide, Dermal repair, Extracellular matrix, Fibroblast activation, Topical serum, Cosmetic research, High purity peptide, Supplier, Manufacturer, Bulk order, Cosmetic raw materialResearch peptide, Pharmaceutical


    If you have any product requirements, please send an email to:business@huanqiukeji9.com;whatsapp:852 7084 6510

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