Afrormosine (CAS NO. 550-79-8) is a high-purity natural isoflavone and methoxylated isoflavone metabolite derived from leguminous plants. This premium research chemical is engineered for advanced non-clinical laboratory studies, serving as a critical reference standard in pharmaceutical, nutraceutical, and botanical research. With a purity level of ≥98% (RP-HPLC), it provides scientists with the reliability needed for precise analytical method development and the quantification of isoflavone profiles using HPLC and LC-MS techniques.
At the molecular level, Afrormosine exhibits sophisticated biological activity, primarily acting as an anti-cancer, anti-inflammatory, and antioxidant agent. It is specifically recognized for its ability to inhibit melanoma cell proliferation (such as B16F10) by modulating AKT and ERK signaling pathways while activating p38 and JNK MAPK pathways. Additionally, it serves as a potent PKC inhibitor, reducing neutrophil degranulation and ROS generation, making it an indispensable lead compound for drug discovery and quality control in the fine chemical industry.
| Product Name | Afrormosine | CAS NO. | 550-79-8 |
|---|---|---|---|
| Molecular Formula | C17H14O5 | Molecular Weight | 298.29 g/mol |
| Appearance | White to off-white crystalline powder | Purity (RP-HPLC) | ≥98% |
| Solubility | Soluble in DMSO, methanol, ethanol | Endotoxin | ≤10 EU/mg |
| Storage Conditions | -20°C, protected from light, dry and sealed | MOQ | 1g |
Certified ≥98% purity via RP-HPLC, ensuring consistent and reproducible results in sensitive analytical assays.
Strategically stocked in the USA for fast transit via DHL, FedEx, and UPS to minimize research downtime.
Produced by partners employing GMP-compliant systems with full traceability and rigorous quality control.
Precise modulation of AKT/ERK pathways, ideal for oncology and immunopharmacology research.
Every batch includes a comprehensive COA, HPLC purity report, and MS chromatograms upon request.
Flexible supply capabilities ranging from gram-level research needs to ton-level industrial production.
Full lifecycle tracking from raw material procurement to final synthesis and purification.
Rigorous laboratory testing utilizing third-party validation to ensure purity standards.
Strict storage protocols at -20°C with continuous monitoring to prevent degradation.
Adherence to international trade standards and pharmaceutical raw material regulations.
Specialized packaging solutions to protect light-sensitive chemicals during air freight.
Professional guidance on solubility, handling, and analytical method development.
| Service Metric | Standard Grade | GlobalTech Premium |
|---|---|---|
| Purity Level | <95% | ≥98% (HPLC Certified) |
| Lead Time | 14-21 Days | 3-7 Days (USA Stock) |
| Documentation | Basic COA | COA + HPLC + MS Report |
| Compliance | Variable | GMP/FDA Partner Standards |
| Stability | Standard Storage | Strict -20°C Light-Protected |
Afrormosine is primarily used as a reference standard for identifying isoflavones in leguminous plant extracts and as a lead compound in studying anti-melanoma and anti-inflammatory mechanisms.
It must be stored at -20°C in a dry and sealed container, strictly protected from light to prevent chemical degradation.
No, Afrormosine is strictly indicated for non-clinical laboratory research and is not a clinically approved therapeutic agent for human or animal administration.
The product is soluble in common laboratory solvents including DMSO, methanol, and ethanol.
We provide a complete documentation package, including a Certificate of Analysis (COA), HPLC purity report, and mass spectrometry (MS) chromatograms.
Yes, we support flexible scaling from gram-level research quantities up to ton-level industrial supply through our GMP-certified partners.