Acetyl hexapeptide-8 CAS NO. 616204-22-9

Acetyl hexapeptide-8 CAS NO. 616204-22-9

Acetyl Hexapeptide-8 (CAS NO. 616204-22-9) is a high-purity synthetic peptide designed for advanced cosmetic applications, especially in anti-aging skincare formulations. As a neurocosmetic peptide, it targets facial expression lines by reducing muscle contractions, resulting in visibly smoother skin. Available as a white to off-white lyophilized powder with ≥95% HPLC purity, it offers excellent solubility and compatibility with various cosmetic bases. This peptide is a scientifically validated ingredient trusted by formulators worldwide for creating effective, non-invasive solutions for wrinkle reduction and skin rejuvenation.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Acetyl Hexapeptide-8
CAS NO.	616204-22-9
Appearance	White to off-white lyophilized powder
Molecular Formula	C₃₄H₆₀N₁₄O₁₂S
Molecular Weight	889.00 g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in water, glycerol, propylene glycol, and ethanol/water mixtures
Endotoxin	< 1.0 EU/mg (if for research/cosmetic grade)
Biological Activity	Neurocosmetic peptide; inhibits SNARE complex formation, reducing neurotransmitter release and muscle contraction (anti-wrinkle activity)
Storage Conditions	Store at -20°C, protected from light and moisture. After reconstitution, store at 2-8°C.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

Acetyl Hexapeptide-8 works by mimicking the N-terminal end of the SNAP-25 protein, a key component of the SNARE complex involved in neurotransmitter release. By competitively inhibiting the formation of the SNARE complex, it reduces the release of catecholamines (such as acetylcholine) at the neuromuscular junction. This leads to decreased muscle contraction intensity and frequency, resulting in the relaxation of facial expression lines and the prevention of new wrinkle formation, without affecting normal muscle function.

2.PRODUCT INDICATIONS

Anti-Aging Skincare: Formulations targeting dynamic wrinkles, such as crow's feet, forehead lines, and frown lines.

Professional Cosmetics: Serums, creams, eye treatments, and targeted correction products.

Preventive Care: Products for younger skin to delay the onset of expression lines.

Combination Therapies: Can be integrated with other anti-aging actives (e.g., antioxidants, retinoids) for enhanced results.

3.CLINICAL EFFICACY OF PRODUCT

Wrinkle Reduction: Clinical studies demonstrate a significant reduction in wrinkle depth and volume, with visible improvements within 4–8 weeks of regular use.

Skin Smoothing: Instrumental measurements confirm enhanced skin texture and reduced roughness.

High Tolerability: Excellent safety profile suitable for all skin types, including sensitive skin, with minimal risk of irritation.

Consumer Satisfaction: High user-reported satisfaction regarding reduced signs of aging and improved skin appearance.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.