Boc-Tyr(tBu)-Aib-OH CAS NO. 126121-07-7
Boc-Tyr(tBu)-Aib-OH CAS NO. 126121-07-7
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Boc-Tyr(tBu)-Aib-OH |
| CAS NO. | 126121-07-7 |
| Appearance | White to off-white crystalline powder |
| Molecular Formula | C₂₃H₃₆N₂O₆ |
| Molecular Weight | 436.55 g/mol |
| Purity (RP-HPLC) | ≥ 95.0% |
| Solubility | Soluble in DMF, DMSO, methanol, chloroform; partially soluble in acetonitrile. |
| Endotoxin | < 1.0 EU/mg (if for research/analytical grade) |
| Biological Activity | Protected dipeptide building block; used in peptide synthesis to introduce conformationally constrained Aib (2-aminoisobutyric acid) residue. |
| Storage Conditions | Store at 2-8°C, protected from light and moisture. |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
As a synthetic peptide building block, Boc-Tyr(tBu)-Aib-OH functions as a key intermediate in constructing biologically active peptides rather than possessing direct biological activity itself. The Aib residue introduces conformational rigidity that can stabilize α-helical or 3₁₀-helical structures in final peptide sequences, while the tyrosine provides sites for potential phosphorylation or receptor interaction. When incorporated into therapeutic peptides, this combination enhances receptor binding specificity, improves proteolytic stability, and increases membrane permeability, leading to peptides with optimized pharmacological properties and therapeutic potential.
2.PRODUCT INDICATIONS
- Peptide Therapeutic Development: Intermediate for synthesizing constrained peptides targeting GPCRs, enzymes, and protein-protein interactions
- Medicinal Chemistry Research: Building block for structure-activity relationship studies in metabolic, neurological, and oncological disorders
- Drug Discovery Programs: Essential component in developing peptide-based drugs with enhanced stability and bioavailability
- Academic Research: Tool for studying peptide conformation, stability, and biological function in various disease models
- Custom Peptide Synthesis: Key material for producing specialized peptides for both research and therapeutic applications
3.CLINICAL EFFICACY OF PRODUCT
- Enhanced Peptide Stability: Proven to increase in vivo half-life and metabolic stability of therapeutic peptides in preclinical models
- Improved Bioavailability: Demonstrated enhanced membrane permeability and tissue distribution in pharmacokinetic studies
- Research Reproducibility: Consistent batch-to-batch quality ensures reliable experimental outcomes in peptide synthesis
- Therapeutic Potential: Successfully utilized in developing peptide candidates showing promise in metabolic, inflammatory, and neurological disorders
- Quality Assurance: Meets stringent pharmaceutical standards for purity, stability, and process consistency
4.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
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