Fmoc-His(Trt)-Aib-OH CAS NO.132622-71-8

Fmoc-His(Trt)-Aib-OH (CAS No. 132622-71-8) is a high-purity, protected dipeptide building block used in peptide synthesis. The specific molecular formula and molecular weight are customized based on client-specified sequence requirements, ensuring precise application in complex peptide assembly for pharmaceutical and biochemical research.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Fmoc-His(Trt)-Aib-OH
CAS NO.	132622-71-8
Appearance	White to off-white crystalline powder
Molecular Formula	C₃₉H₃₇N₅O₅
Molecular Weight	667.7 g/mol
Amino Acid Sequence	Fmoc-His(Trt)-Aib-OH
Purity (RP-HPLC)	≥98.0%
Solubility	Soluble in DMF, DMSO, and dichloromethane; slightly soluble in methanol; insoluble in wate
Endotoxin	< 1.0 EU/mg
Biological Activity	Protected peptide building block used in solid-phase peptide synthesis (SPPS) for the introduction of conformationally constrained residues, facilitating the study of peptide structure-activity relationships and drug design.
Storage Conditions	Store at 2-8°C, protected from light and moisture.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

This compound acts as a key intermediate in solid-phase peptide synthesis, where the Fmoc and trityl protecting groups enable controlled, sequential coupling of amino acids. Its structure supports the formation of peptide bonds while maintaining stability during synthesis, particularly for introducing conformationally constrained residues.

2.PRODUCT INDICATIONS

Fmoc-His(Trt)-Aib-OH is primarily used in the synthesis of therapeutic peptides, enzyme inhibitors, and bioactive compounds. It is also applied in research focusing on drug design, structural biology, and the development of peptide-based pharmaceuticals.

3.CLINICAL EFFICACY OF PRODUCT

As a research-grade building block, this compound itself is not used directly in clinical applications. Its value lies in enabling the production of high-purity, structurally defined peptides, which may later undergo preclinical and clinical evaluation for potential therapeutic effects in areas such as oncology, metabolic disorders, or infectious diseases.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.