Tripeptide-29 CAS NO.2239-67-0

Tripeptide-29 CAS NO.2239-67-0

Tripeptide-29 CAS NO.2239-67-0

Tripeptide-29 CAS NO.2239-67-0

Tripeptide-29 CAS NO.2239-67-0

Tripeptide-29 (CAS NO. 2239-67-0) is a synthetic tripeptide, also widely recognized by its sequence name Gly-His-Lys (GHK). It is a naturally occurring copper-binding peptide found in human plasma and tissues, known for its powerful regenerative and protective properties. This multifunctional peptide is a premier ingredient in anti-aging skincare, wound healing formulations, and biomedical research due to its ability to promote tissue repair, stimulate collagen synthesis, and modulate inflammatory responses.


TECHNICAL SPECIFICATIONS

Item
Specification
Product Name
Tripeptide-29
CAS NO.
2239-67-0
Appearance
White to off-white lyophilized powder
Molecular Formula
C₁₄H₂₄N₄O₅
Molecular Weight
344.36 g/mol
Amino Acid SequenceLys-Val-Lys (K-V-K)
Purity (RP-HPLC)
≥ 98.0%
Solubility

Soluble in water, easy to dissolve in dilute aqueous solutions; slightly soluble in methanol and ethanol

Endotoxin< 1.0 EU/mg
Biological Activity
Exhibits potent skin firming and anti-aging effects by stimulating collagen and elastin synthesis, improving skin elasticity and reducing the appearance of fine lines and wrinkles
Storage Conditions
Store at -20°C in a cool, dry place, protected from light and moisture; avoid repeated freeze-thaw cycles
Stock Location
Stock in USA
MOQ
1g


1. Mechanism of Action

Tripeptide-29 (GHK) functions through a multi-targeted regenerative signaling mechanism:

  • Copper Chelation & Delivery: It has a high affinity for copper ions, forming the GHK-Cu complex. This complex acts as a signaling molecule and delivers bioavailable copper to cells, which is a crucial cofactor for enzymes like lysyl oxidase (involved in collagen/elastin cross-linking) and superoxide dismutase (a key antioxidant enzyme).

  • Gene Expression Modulation: GHK influences the expression of over 4,000 human genes, shifting cellular activity from a state of damage/inflammation to a state of repair and regeneration. It upregulates genes for collagen, elastin, glycosaminoglycans (GAGs), and cell-protective antioxidants.

  • Anti-inflammatory & Antioxidant Action: It reduces the expression of inflammatory cytokines and directly scavenges free radicals, creating an optimal environment for healing.

  • Cellular Attraction: It acts as a chemoattractant for immune and repair cells to the site of damage.

2. Product Indications 

Improves skin aging: Provides non-invasive anti-aging solutions for dynamic wrinkles, static wrinkles, and skin laxity.

Barrier function repair: Suitable for skin barrier damage caused by dryness, sensitivity, over-cleansing, or post-cosmetic procedures.

Improved skin texture: Improves rough skin, lack of elasticity, and insufficient radiance.

Synergistic effect: As a base active ingredient, it can synergize with ingredients such as retinol, vitamin C, and hyaluronic acid to enhance overall anti-aging and repair effects.

3. Clinical Efficacy of Product

Tripeptide-29 (GHK) is one of the most extensively studied peptides in regenerative medicine and cosmeceuticals. A substantial body of clinical and preclinical evidence supports its efficacy:

  • Skin Rejuvenation: Proven to significantly improve skin firmness, elasticity, and hydration while reducing wrinkle depth and photodamage.

  • Wound Healing: Clinically shown to accelerate wound closure, reduce inflammation, and promote the regeneration of healthy tissue in various wound models.

  • Hair Growth: Studies demonstrate its ability to stimulate hair follicle activity and promote hair regrowth.

  • Systemic Benefits: Research indicates potential systemic benefits for tissue repair, anti-inflammatory effects, and organ protection.

    4.Certificate

    • GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

    Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


    We prioritize:

    1.A rigorous quality management system

    2.Batch traceability and stability data

    3.Professional laboratory testing and validation

    4.Compliance with international trade standards


    Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

    5.DELIVERY & SHIPPING

    We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

    Professional and Secure Packaging

    Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

    We can also customize packaging according to customer needs.

    Shipping Methods 

    Main Method: International Air Freight

    We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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    Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

    We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


    Hot Tags: Pentapeptide-25, Anti-aging peptide, Collagen booster, Skin firming, Wrinkle reducer, Cosmetic ingredient, Peptide synthesis, Skincare, CAS 1000313-64-36, Synthetic peptide, Dermal repair, Extracellular matrix, Fibroblast activation, Topical serum, Cosmetic research, High purity peptide, Supplier, Manufacturer, Bulk order, Cosmetic raw materialResearch peptide, Pharmaceutical


    If you have any product requirements, please send an email to:business@huanqiukeji9.com;whatsapp:852 7084 6510

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