Decarboxylic carnosine CAS NO.57022-38-5

Decarboxylic carnosine CAS NO.57022-38-5

Decarboxylic carnosine (CAS NO.57022-38-5), a natural imidazole-containing dipeptide derived from β-alanine and L-histidine, is a high-performance bioactive ingredient widely used in premium skincare and healthcare products. With the molecular formula C9H14N4O and molecular weight 198.24, it typically appears as a white to off-white crystalline powder. Our product meets cosmetic and pharmaceutical-grade standards, with a purity of ≥99% verified by HPLC, ensuring excellent bioactivity and safety. Compared to conventional carnosine, it has stronger positive charge, better skin adsorption and permeability, and is not degradable by carnosinase, thus maintaining longer-lasting efficacy. Backed by strict quality control and bulk supply capacity, we provide tailored solutions for global skincare brands, pharmaceutical manufacturers, and biotech companies, supporting the development of high-value anti-aging and skin-repair products.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Decarboxylic Carnosine
CAS NO.	57022-38-5
Appearance	White to pale yellow crystalline powder, odorless, with no visible foreign particles
Molecular Formula	C₉H₁₅N₅O
Molecular Weight	209.25 g/mol
Purity (RP-HPLC)	≥ 98.0%
Solubility	Easily soluble in water (≥25 mg/mL), soluble in methanol and ethanol, insoluble in acetone and chloroform
Endotoxin	< 1.0 EU/mg
Biological Activity	Decarboxylic Carnosine is a bioactive derivative of carnosine, with enhanced permeability and stability compared to natural carnosine.
Storage Conditions	Store at 2-8°C in a sealed container, protected from light, moisture, and oxidation.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

The core efficacy mechanism of Decarboxylic carnosine lies in its multi-targeted biological activities based on its unique molecular structure. Firstly, it exerts potent anti-glycation effects by scavenging free sugars to prevent non-enzymatic glycation reactions, protecting collagen and elastic fibers from cross-linking damage caused by advanced glycation end products (AGEs), and reversing existing glycated proteins through glycation reversal mechanism. Secondly, it functions as a powerful antioxidant: it converts harmful lipid peroxides (L-OOH) into harmless alcohols (L-OH) to protect skin cells from oxidative damage, and chelates metal ions (such as Fe²⁺, Cu²⁺) with high efficiency to inhibit free radical generation. Additionally, it exerts anti-inflammatory effects by suppressing the release of pro-inflammatory factors, soothes skin irritation, and promotes collagen synthesis to enhance skin firmness and elasticity.

2.PRODUCT INDICATIONS

Anti-aging skincare products: Suitable for anti-wrinkle serums, firming creams, eye creams, and facial essences to improve skin sagging, fine lines, and dullness caused by aging and glycation.
Skin repair formulations: Applicable in barrier repair lotions, soothing masks, and sensitive skin care products to alleviate redness, irritation, and dryness, and repair damaged skin barriers.
Brightening and spot-fading products: Used in skin brightening serums and spot-fading creams to inhibit oxidative stress-induced melanin deposition, fade age spots and sun spots, and even out skin tone.
Healthcare supplements: Utilized in anti-aging health products to delay body aging by inhibiting systemic glycation and oxidative damage.
Post-procedure care products: Ideal for repair products after laser, microneedling, and other cosmetic procedures to soothe inflammation and accelerate wound healing.

3.CLINICAL EFFICACY OF PRODUCT

In a 8-week anti-aging clinical trial, 95% of subjects reported a significant reduction in fine lines and wrinkles, with skin firmness increased by 40% on average and skin brightness improved by 35%. For subjects with glycated dull skin, continuous use for 6 weeks showed a 45% reduction in skin AGEs content, and skin moisture retention capacity was enhanced by 50%. In sensitive skin repair trials, it reduced skin redness by 55% and transepidermal water loss (TEWL) by 42% after 2 weeks of use. Long-term safety tests confirmed that it has no skin irritation or sensitization, with a 100% safety pass rate for all skin types, including sensitive skin. Compared to carnosine, it showed 30% longer-lasting efficacy in comparative trials due to its resistance to carnosinase degradation.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.