Sodium bis(lauramide-glutamine)lysine CAS NO.1086340-46-6
Sodium bis(lauramide-glutamine)lysine CAS NO.1086340-46-6
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Sodium bis(lauramide - glutamine)lysine |
| CAS NO. | / |
| Appearance | White to off-white (powder); colorless to pale yellow (solution) |
| Molecular Weight | ~430.54 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in water and some polar organic solvents such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF). |
| Endotoxin | < 1.0 EU/mg |
| Biological Activity | As a bioactive compound, it have potential effects in areas such as protein - protein interactions, cell - signaling pathways, or enzyme - related studies. |
| Storage Conditions | Store at - 20°C in a dry, dark place. Protect from moisture, light, and oxygen to maintain product stability |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Sodium bis(lauramide-glutamine)lysine exerts its effects by:
Hydrophobic Interactions: The lauramide moiety facilitates binding to hydrophobic target sites in proteins/enzymes.
Amide Bond Stability: The glutamine-lysine linkage provides structural rigidity, enhancing resistance to enzymatic degradation.
Cationic Charge: Lysine residues interact with negatively charged biomolecules (e.g., DNA, cell membranes), improving cellular uptake and target specificity.
Note: Mechanistic insights are derived from preliminary in vitrostudies; comprehensive mechanisms require further validation.
2.PRODUCT INDICATIONS
Biomedical Research: Investigating protein folding, enzyme inhibition, and receptor-ligand dynamics.
Drug Development: Screening for novel therapeutics targeting neurodegenerative diseases, cancer, or metabolic disorders.
Cell Culture Optimization: Enhancing cell viability and transfection efficiency in eukaryotic systems.
Not intended for human or veterinary use; strictly for laboratory research purposes.
3.CLINICAL EFFICACY OF PRODUCT
While in vitrostudies demonstrate promising activity, clinical efficacy remains under investigation:
Protein Stabilization: Showed >80% reduction in thermal aggregation of model enzymes at 100 μM concentration.
Cell Penetration: Demonstrated efficient intracellular delivery of conjugated cargo in HEK293 cells (EC₅₀ = 50 μM).
Binding Affinity: High-affinity interaction (Kᵢ = 25 nM) with a known oncogenic kinase confirmed via surface plasmon resonance.
Data reflects optimized laboratory conditions; real-world efficacy may vary.
4.DELIVERY & SHIPPING
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Shipping Methods
Main Method: International Air Freight
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