Aviptadil CAS NO.40077-57-4
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Aviptadil |
| CAS NO. | 40077-57-4 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C147H238N44O42S |
| Molecular Weight | 3326.08 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in water or acidic aqueous solution |
| Endotoxin | < 0.1 EU/mg |
| Biological Activity | Potent vasoactive intestinal peptide analog; exhibits anti-inflammatory & pulmonary protective effects |
| Storage Conditions | Store at 2–8°C, protected from light and moisture |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Aviptadil exerts its effects by selectively binding to VPAC1 and VPAC2 receptors highly expressed on alveolar type II (AT2) cells, which are crucial for surfactant production and lung repair. This binding triggers intracellular cAMP signaling, leading to a multi-faceted protective response: it significantly inhibits the production of pro-inflammatory cytokines like IL-6 and TNF-α, blocks viral-induced caspase-3 activation to prevent apoptosis of lung cells, and promotes surfactant synthesis. Additionally, it induces bronchodilation and pulmonary vasodilation, collectively working to reduce inflammation, protect against further lung damage, and improve oxygenation in compromised patients.
2.PRODUCT INDICATIONS
The primary focus of Aviptadil is the treatment of critical respiratory disorders, including Acute Respiratory Distress Syndrome (ARDS) and respiratory failure in critically ill COVID-19 patients. It is also investigated for use in pulmonary arterial hypertension (PAH), pulmonary fibrosis, and sarcoidosis. The product is intended for hospitalized patients experiencing severe hypoxemia or those at high risk of progressing to mechanical ventilation, offering a potential therapeutic option where standard care has been insufficient. It is often utilized in ICU settings or clinical trials for individuals requiring advanced life support due to acute lung injury.
3.CLINICAL EFFICACY OF PRODUCT
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags:Aviptadil, VIP, RLF100, ZYESAMI, ARDS, COVID19, RespiratoryFailure, PulmonaryHypertension, CriticalCare, CytokineStorm, LungInjury, PeptideTherapy, NeuroRx, ClinicalTrials, Supplier, Manufacturer, Bulk order, Pharmaceutical.
If you have any product requirements, please send an email to:info@huanqiukeji9.com;whatsapp:85246842553
