Argipressin Acetate CAS-NO.113-79-1

Argipressin Acetate is a synthetic nonapeptide analog of the endogenous hormone arginine vasopressin (AVP), formulated as an acetate salt to enhance stability and solubility for pharmaceutical and research use. It is a key reference standard and active pharmaceutical ingredient (API) for studies in endocrinology, nephrology, and critical care, known for its dual antidiuretic and vasoconstrictive properties. This high-purity peptide is essential for developing diagnostic tests and therapeutic interventions targeting water balance and vascular tone.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Argipressin Acetate
CAS NO.	CAS-NO.113-79-1
Appearance	White to off-white lyophilized powder
Molecular Formula	C₄₆H₆₅N₁₅O₁₂S₂ • xC₂H₄O₂
Molecular Weight	1084.2 g/mol
Amino Acid Sequence	H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH₂
Purity (RP-HPLC)	≥ 98.0%
Solubility	Soluble in water, dilute acetic acid, and polar solvents; may require mild acid for complete dissolution.
Endotoxin	< 1.0 EU/mg
Biological Activity	Potent V1a/V2 receptor agonist; activity confirmed by in vitro vasoconstriction or antidiuretic assays (specific activity provided per batch).
Storage Conditions	Store at -20°C or below, in a dry, dark environment. After reconstitution, store at 2-8°C and use within 24 hours.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

Argipressin Acetate functions as a potent agonist of vasopressin receptors, binding to V1a receptors on vascular smooth muscle to induce vasoconstriction and increase blood pressure, while also activating V2 receptors in the renal collecting ducts to promote water reabsorption via aquaporin-2 channels. This dual mechanism effectively regulates osmoregulation and systemic vascular resistance, making it a critical agent for research in hemodynamic stability and renal function, particularly in models of shock and fluid imbalance

2.PRODUCT INDICATIONS

This product is indicated for research and development of treatments for central diabetes insipidus, where it addresses polyuria and polydipsia by restoring antidiuretic hormone activity. It is also used in cardiovascular research for managing vasodilatory shock, septic shock, and bleeding esophageal varices due to its potent vasopressor effects. Additionally, it serves as a tool compound in pharmacological assays to study receptor signaling and evaluate novel V1a/V2 receptor antagonists or agonists.

3.CLINICAL EFFICACY OF PRODUCT

Clinical studies and therapeutic use have demonstrated that Argipressin Acetate effectively reduces urine output and corrects hypernatremia in diabetes insipidus patients, while in critical care settings, it significantly increases mean arterial pressure and reduces catecholamine requirements in shock states. Its rapid onset of action and predictable pharmacokinetics support its role as a reliable intervention for stabilizing hemodynamic parameters and improving outcomes in life-threatening conditions.

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4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

Hot Tags: ArgipressinAcetate #ArginineVasopressin #VasopressinAgonist #AntidiureticHormone #DiabetesInsipidus #Vasopressor #AVP #PeptideAPI

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