Survodutide CAS NO.2805997-46-8
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Survodutide |
| CAS NO. | 2805997-46-8 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C192H289N47O61 |
| Molecular Weight | 4231.62 g/mol |
| Purity (RP-HPLC) | ≥98.0% |
| Solubility | Soluble in water or aqueous buffers (e.g., PBS, pH 7.4); reconstitution required |
| Endotoxin | ≤1 EU/mg |
| Biological Activity | Dual agonist of GLP-1R and GCGR; promotes weight loss, improves glycemic control, and modulates hepatic lipid metabolism |
| Storage Conditions | Store at 2–8°C protected from light; do not freeze |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Survodutide operates through a synergistic dual-receptor activation strategy, where its GLP-1R agonism component reduces food intake and delays gastric emptying to lower energy intake, while its GCGR agonism component directly increases hepatic energy expenditure by promoting fatty acid oxidation and reducing de novo lipogenesis in the liver. This dual-action approach not only facilitates significant weight reduction but also directly targets hepatic steatosis and inflammation, offering a mechanism that is partially independent of weight loss for improving liver health, which is a distinct advantage over single GLP-1 receptor agonists.
2.PRODUCT INDICATIONS
This product is indicated for use as a reference standard in HPLC analysis for the quantification of anthocyanins in plant extracts and food products. In the development of health supplements, it is targeted for formulations aimed at supporting cardiovascular health, anti-aging, and cellular protection. It is also suitable for research into chemoprevention, particularly for breast and leukemia cell lines, and for studies investigating natural colorants in the food and cosmetic industries.
3.CLINICAL EFFICACY OF PRODUCT
Clinical trial data, notably from the Phase 2 study published in the New England Journal of Medicine, demonstrated that after 48 weeks of treatment, up to 83% of MASH patients achieved histological improvement without worsening of fibrosis, and up to 64.5% achieved an improvement in fibrosis stage without worsening of MASH, significantly outperforming placebo. Additionally, the therapy led to a mean body weight reduction of up to 19% in obese patients without diabetes, alongside substantial reductions in liver fat content and improvements in non-invasive fibrosis biomarkers, establishing its robust efficacy profile for both liver disease resolution and substantial weight management.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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