Octreotide Acetate CAS NO.83150-76-9/79517-01-4

Octreotide Acetate CAS NO.83150-76-9/79517-01-4

Octreotide Acetate CAS NO.83150-76-9/79517-01-4

Octreotide Acetate CAS NO.83150-76-9/79517-01-4

Octreotide Acetate CAS NO.83150-76-9/79517-01-4

Octreotide Acetate is a synthetic cyclic octapeptide and a long-acting analogue of the natural hormone somatostatin. It is designed to overcome the limitations of native somatostatin by offering a significantly prolonged duration of action, making it suitable for chronic management of hormone-related disorders. Available in both immediate-release and long-acting release (LAR) depot formulations, this injectable product is a cornerstone in the treatment of rare endocrine conditions, providing sustained control over pathological hormone secretion with reduced dosing frequency compared to conventional therapies.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Octreotide Acetate
CAS NO.
83150-76-9/79517-01-4
Appearance
White to off-white powder
Molecular Formula
C49H64N10O10S2
Molecular Weight
 1019.24 g/mol
Purity (RP-HPLC)
≥ 98.0%
Solubility

Soluble in water; slightly soluble in methanol; insoluble in ethanol

Endotoxin≤0.1 EU/mg
Biological Activity
Potent somatostatin receptor agonist; inhibits GH, glucagon, insulin release
Storage Conditions
Store at 2–8°C, protected from light; avoid freezing
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

Octreotide Acetate functions as a potent somatostatin receptor agonist, binding with high affinity to somatostatin receptor subtypes (primarily SSTR2 and SSTR5) expressed on target tissues. Its primary pharmacological action is the suppression of excessive hormone secretion; it potently inhibits the release of growth hormone (GH), glucagon, and insulin, and reduces the secretion of gastroenteropancreatic peptides such as gastrin, vasoactive intestinal peptide (VIP), and serotonin. Additionally, it exerts a physiological effect by reducing splanchnic blood flow, which is critical in managing gastrointestinal bleeding. This multifaceted mechanism makes it effective in controlling symptoms driven by hormonal hypersecretion and in stabilizing hemodynamic conditions.

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2.PRODUCT INDICATIONS

This product is indicated for a specialized patient population, primarily targeting rare neuroendocrine and growth disorders. Key approved uses include the long-term management of acromegaly to reduce elevated GH and IGF-1 levels in patients inadequately controlled by surgery or radiation, and the symptomatic treatment of gastroenteropancreatic neuroendocrine tumors (GEP-NETs), including carcinoid syndrome (flushing, diarrhea), VIPomas, and glucagonomas. It is also utilized in clinical settings for the emergency treatment of esophageal variceal bleeding in cirrhotic patients and for the prevention of complications following pancreatic surgery, addressing both chronic endocrine imbalances and acute critical care needs.

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3.CLINICAL EFFICACY OF PRODUCT

Clinical studies have demonstrated that Octreotide Acetate provides significant and rapid symptomatic relief. In acromegaly, long-term therapy normalizes GH and IGF-1 levels in a majority of patients, leading to improvements in soft tissue swelling and headache. For patients with functional GEP-NETs, it effectively controls debilitating symptoms such as severe diarrhea and flushing, with long-acting formulations (LAR) showing comparable efficacy to daily subcutaneous injections while significantly improving quality of life through less frequent dosing. Real-world evidence also supports its role in reducing rebleeding rates in variceal hemorrhage and mitigating fistula formation post-pancreatectomy, establishing it as a versatile agent with proven efficacy across its labeled indications.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.


Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


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If you have any product requirements, please send an email to:info@huanqiukeji9.com;whatsapp:85246842553

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