Carperitide ( ANP (1-28), human ) CAS NO.89213-87-6
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Carperitide ( ANP (1-28), human ) |
| CAS NO. | 89213-87-6 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C127H203N45O39S3 |
| Molecular Weight | 3080.44 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in water; reconstitute with sterile distilled water or PBS |
| Endotoxin | ≤0.1 EU/mg |
| Biological Activity | Potent vasodilator and natriuretic agent; activates NPR-A, increases cGMP |
| Storage Conditions | Store at 2–8°C, protected from light; stable for 24 months unopened |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Carperitide exerts its therapeutic effects by binding to natriuretic peptide receptor-A (NPR-A) on target cells, activating guanylyl cyclase to increase intracellular cyclic guanosine monophosphate (cGMP) levels. This signaling cascade induces potent vasodilation in both arteries and veins, effectively reducing systemic vascular resistance (afterload) and central venous pressure (preload). Simultaneously, it acts directly on the kidneys to inhibit sodium reabsorption in the collecting ducts, producing a natriuresis and diuresis distinct from loop diuretics. Furthermore, it suppresses the renin-angiotensin-aldosterone system (RAAS) and sympathetic nervous system, providing a comprehensive counter-regulatory approach to heart failure pathophysiology.
2.PRODUCT INDICATIONS
Carperitide is clinically indicated for the treatment of acute decompensated heart failure, particularly in patients presenting with dyspnea and pulmonary congestion due to volume overload. It is also investigated for use in perioperative settings, such as during cardiac surgery, to maintain hemodynamic stability and protect renal function. The product is targeted at healthcare providers managing hospitalized patients who require rapid unloading therapy and have adequate blood pressure to tolerate vasodilation. Additionally, it serves as a critical research tool in preclinical studies focusing on cardiovascular pharmacology, hypertension models, and renal function assessment.
3.CLINICAL EFFICACY OF PRODUCT
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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