PNC27 peptide

PNC27 Peptide (CAS No. Confidential) is a high-purity synthetic peptide derived from the p53 tumor suppressor protein. The molecular formula and molecular weight are customized based on the specific sequence and modifications requested by the client, ensuring precise performance in targeted oncology and apoptosis research.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	PNC27 Peptide
CAS NO.
Appearance
Molecular Formula	C188H293N53O44S
Molecular Weight	4032.13g/mol
Amino Acid Sequence
Purity (RP-HPLC)	≥95.0% (can be customized to ≥98.0%)
Solubility	Soluble in water, PBS, or dilute acetic acid solution
Endotoxin	< 1.0 EU/mg
Biological Activity	Designed to bind to mutant p53 in cancer cells and induce selective apoptosis; used in oncology research and anticancer drug development studies.
Storage Conditions	Store at –20°C, protected from light and moisture. For long-term storage, recommend –80°C.
Stock Location	Stock in USA
MOQ	10mg

1.MECHANISM OF ACTION

This peptide functions by binding selectively to the cell membrane-bound form of mutant p53 in cancer cells, forming pores that disrupt membrane integrity and induce rapid, caspase-independent apoptosis. This targeted mechanism allows it to eliminate cancer cells while sparing normal cells that do not express the mutant protein.

2.PRODUCT INDICATIONS

PNC27 Peptide is primarily applied in cancer research, especially for studying p53-related tumor biology and developing novel apoptosis-inducing therapies. It is used in preclinical studies for solid tumors, hematological malignancies, and drug resistance research, as well as in investigations of targeted cancer cell elimination strategies.

3.CLINICAL EFFICACY OF PRODUCT

Preclinical studies demonstrate that PNC27 Peptide effectively inhibits tumor growth and induces cancer cell death in various models, including colon, breast, and pancreatic cancers. Its specificity for mutant p53-expressing cells enhances its therapeutic potential, though clinical efficacy in humans is still under evaluation in ongoing trials.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.

Shipping Methods

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.