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Secretin Acetate CAS NO.17034-35-4/CAS NO. 10813-74-8

Secretin Acetate is a high-purity, synthetic 27-amino-acid peptide hormone formulated for diagnostic and therapeutic applications in gastroenterology. Derived from the natural gastrointestinal hormone secretin, this peptide acts as a potent stimulator of pancreatic bicarbonate secretion and gastric acid inhibitor. Available as a white to off-white lyophilized powder with verified biological activity, it is manufactured under stringent quality standards to ensure consistency and reliability. Our pharmaceutical-grade product is ideal for pancreatic function testing, gastrointestinal disorder diagnosis, and advanced research in digestive physiology.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Secretin Acetate
CAS NO.	10813-74-8/17034-35-4
Appearance	White to off-white (powder); colorless to pale yellow (solution)
Molecular Formula	C130H220N44O41
Molecular Weight	3055.41 g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in water, 0.9% sodium chloride injection, and 5% dextrose injection
Endotoxin	< 1.0 EU/mg
Biological Activity	Gastrointestinal hormone; stimulates pancreatic bicarbonate and fluid secretion, inhibits gastric acid secretion, and regulates duodenal pH.
Storage Conditions	Store at 2-8°C, protected from light and moisture. After reconstitution, use immediately or store as directed.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

Secretin Acetate functions by binding to specific secretin receptors (SCTR) located on pancreatic ductal cells and gastric parietal cells. This receptor activation stimulates adenylate cyclase, increasing intracellular cAMP levels, which in turn promotes the secretion of bicarbonate-rich fluid from the pancreas and inhibits gastric acid production. The result is enhanced neutralization of duodenal acidity, optimized digestive enzyme activity, and regulated gastrointestinal pH balance.

2.PRODUCT INDICATIONS

Pancreatic Function Testing: Diagnostic assessment of exocrine pancreatic insufficiency and chronic pancreatitis

Gastrinoma Diagnosis: Secretin stimulation test for Zollinger-Ellison syndrome confirmation

Gastrointestinal Research: Studies of digestive hormone physiology and pancreatic secretion mechanisms

Therapeutic Applications: Adjunct management of duodenal ulcers and pancreatic insufficiency

Pharmaceutical Development: Active ingredient for diagnostic kits and gastrointestinal formulations

3.CLINICAL EFFICACY OF PRODUCT

Diagnostic Accuracy: High sensitivity and specificity in detecting pancreatic dysfunction and gastrin-secreting tumors

Rapid Response: Measurable increase in pancreatic bicarbonate secretion within 30-60 minutes post-administration

Therapeutic Benefit: Effective reduction in gastric acidity and improvement in duodenal ulcer healing rates

Safety Profile: Well-tolerated with minimal adverse effects, primarily transient flushing or nausea

Quality Assurance: ≥95% HPLC purity with batch-to-batch consistency and validated biological activity

Regulatory Compliance: Manufactured in accordance with pharmacopeial standards for diagnostic and therapeutic use

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.