TECHNICAL SPECIFICATIONS
Item
| Specification
|
|---|
Product Name
| Lypressin Acetate
|
CAS NO.
| 50-57-7 |
Appearance
| White to off-white lyophilized powder
|
Molecular Formula
| C46H65N13O12S2
|
Molecular Weight
| 1056.22 g/mol |
Purity (RP-HPLC)
| ≥ 95.0% |
Solubility
| Soluble in water, dilute acetic acid, and physiological saline. |
| Endotoxin | < 1.0 EU/mg
|
Biological Activity
| Synthetic vasopressin analog; acts as an antidiuretic hormone (ADH) via V2 receptors; also has vasoconstrictive activity via V1a receptors.
|
Storage Conditions
| Store at 2-8°C, protected from light and moisture. After reconstitution, use immediately or store as directed.
|
Stock Location
| Stock in USA
|
MOQ
| 1g |
1.MECHANISM OF ACTION
Fibronectin CS-1 Peptide exerts its biological effects through high-affinity binding to the α4β1 integrin receptor (VLA-4) expressed on leukocytes, endothelial cells, and certain tumor cells. The peptide's LDV (Leu-Asp-Val) motif serves as the core recognition sequence that mimics the natural binding site in fibronectin. Upon binding to α4β1 integrin, it triggers intracellular signaling cascades that can either promote or inhibit cell adhesion, migration, and activation, depending on the cellular context.
2.PRODUCT INDICATIONS
Cell Adhesion Studies: As a specific ligand or competitive inhibitor in assays investigating α4β1 integrin-mediated cell adhesion and migration.
Inflammation Research: To study leukocyte trafficking, endothelial cell interactions, and inflammatory responses in experimental models.
Cancer Metastasis Research: As a tool to investigate the role of integrin-mediated adhesion in tumor cell invasion and metastasis.
Biomaterial Functionalization: For coating surfaces to promote or modulate specific cell adhesion in tissue engineering applications.
Drug Discovery: As a lead compound or screening tool for developing novel anti-inflammatory or anti-metastatic agents targeting α4β1 integrin.
3.CLINICAL EFFICACY OF PRODUCT
As a research reagent, Fibronectin CS-1 Peptide itself is not approved for clinical use. Its "efficacy" is demonstrated in preclinical research settings. Studies show that this peptide can effectively inhibit α4β1 integrin-mediated cell adhesion in vitro with IC50 values in the micromolar range. In animal models of inflammation, administration of CS-1 peptide has been shown to reduce leukocyte infiltration and tissue damage. In experimental metastasis models, the peptide has demonstrated the ability to inhibit tumor cell adhesion to endothelial cells and reduce metastatic colonization. However, these effects are context-dependent and require further validation.
4.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
