TECHNICAL SPECIFICATIONS
Item
| Specification
|
|---|
Product Name
| Galanin, porcine
|
CAS NO.
| 88813-36-9 |
Appearance
| White to off-white lyophilized powder
|
Molecular Formula
| C146H213N43O40
|
Molecular Weight
| 3210.55 g/mol |
Purity (RP-HPLC)
| ≥ 95.0% |
Solubility
| Soluble in water, acetic acid (0.1%), DMSO; may require gentle vortexing or sonication |
| Endotoxin | < 1.0 EU/mg
|
Biological Activity
| Neuropeptide; inhibits insulin secretion, modulates neurotransmitter release, and regulates feeding behavior, nociception, and memory.
|
Storage Conditions
| Store at -20°C or below, protected from light and moisture. After reconstitution, aliquot and store at -20°C.
|
Stock Location
| Stock in USA
|
MOQ
| 1g |
1.MECHANISM OF ACTION
Galanin, porcine functions primarily by binding to and activating G-protein coupled galanin receptors (GalR1, GalR2, and GalR3). This interaction modulates intracellular signaling pathways, including inhibition of adenylate cyclase and regulation of ion channels, leading to reduced neurotransmitter release (such as acetylcholine, norepinephrine, and glutamate), altered neuronal excitability, and downstream effects on hormone secretion, feeding behavior, and nociception. Its action is highly conserved across species, making it a reliable tool for translational neuroscience and endocrine research.
2.PRODUCT INDICATIONS
Neuroscience Research: Investigation of synaptic transmission, learning and memory, anxiety, depression, and neurodegenerative diseases.
Endocrine Studies: Exploration of insulin secretion, growth hormone regulation, and metabolic disorders.
Pain and Nociception: Research on galanin’s role in modulating pain pathways and inflammatory responses.
Feeding Behavior and Obesity: Studies on appetite regulation, energy homeostasis, and related metabolic syndromes.
Drug Discovery: Screening and development of galanin receptor-targeted therapeutics for neurological and endocrine disorders.
3.CLINICAL EFFICACY OF PRODUCT
Validated Biological Activity: Demonstrated potent receptor binding and functional modulation in cell-based and animal models.
High Purity: ≥95% by RP-HPLC with confirmed amino acid sequence and molecular weight via mass spectrometry.
Reproducible Research Outcomes: Consistent performance in neurotransmitter release assays, hormone secretion studies, and behavioral tests.
Translational Relevance: Supports preclinical studies on epilepsy, Alzheimer’s disease, diabetes, and chronic pain.
Quality Assurance: Produced under GLP-like conditions with low endotoxin levels suitable for in vitro and in vivo applications.
Regulatory Compliance: Suitable for use in FDA- and EMA-relevant research and drug development pipelines.
4.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
