Galanin Message Associated Peptide (1-41), amide

Galanin Message Associated Peptide (1-41), amide, also known as GMAP (1-41), amide or Preprogalanin (65-105), amide, is a synthetic 41-amino acid neuropeptide derived from the C-terminal region of preprogalanin. This high-purity peptide exhibits a range of biological activities, including antimicrobial, immunomodulatory, and neuroprotective effects. Available as a white to off-white lyophilized powder with HPLC-verified purity, it is designed for advanced research in neuroscience, immunology, and infectious disease. Our product is manufactured under stringent quality controls to ensure consistent performance in both in vitro and in vivo studies, making it a valuable tool for investigating galanin-related pathways and host defense mechanisms.

Send Email

Download

TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Galanin Message Associated Peptide (1-41), amide; GMAP (1-41), amide; Preprogalanin (65-105), amide
CAS NO.	/
Appearance	White to off-white lyophilized powder
Molecular Formula	C206H326N56O64S
Molecular Weight	4643.3 g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in water, dilute acetic acid, DMSO; gentle solubilization may be required.
Endotoxin	< 1.0 EU/mg
Biological Activity	Glycol-associated peptide (GMAP) is a C-terminal processing product of preprogalanin and possesses antibacterial, immunomodulatory, and neuroprotective activities; it can affect pain perception, inflammatory responses, and behavior.
Storage Conditions	Store at -20°C or below, protected from light and moisture. After reconstitution, aliquot and store at -20°C
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

GMAP (1-41), amide functions through multiple pathways, including modulation of galanin receptors and direct antimicrobial activity. It binds to galanin receptors (GalR1, GalR2, GalR3) to influence neurotransmitter release, pain perception, and stress responses. Additionally, its amphipathic structure enables membrane disruption in microbial cells, providing broad-spectrum antimicrobial effects. The peptide also modulates cytokine production and immune cell activity, linking neural and immune system functions in health and disease.

2.PRODUCT INDICATIONS

Neuroscience Research: Study of galanin signaling, pain modulation, stress responses, and neurodegenerative disorders

Immunology & Infection Research: Investigation of antimicrobial peptides, host defense mechanisms, and sepsis models

Psychiatric & Behavioral Studies: Exploration of anxiety, depression, and stress-related behaviors

Drug Discovery: Screening for novel antimicrobial, neuroprotective, or immunomodulatory agents

Preclinical Disease Models: Use in animal models of infection, inflammation, chronic pain, and neurological conditions

3.CLINICAL EFFICACY OF PRODUCT

Validated Bioactivity: Demonstrated antimicrobial, neuroprotective, and immunomodulatory effects in experimental models

High Purity: ≥95% purity by RP-HPLC with mass spectrometry confirmation of sequence and amidation

Research Reproducibility: Consistent performance in antimicrobial assays, cytokine studies, and behavioral tests

Broad Application Scope: Suitable for microbiological, cellular, immunological, and neuropharmacological experiments

Quality Assurance: Produced under controlled conditions with low endotoxin levels for research use

Translational Relevance: Supports studies on novel therapeutic strategies for infections, inflammatory diseases, and neurological disorders

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.