Ghrelin (Rat) CAS NO.258338-12-4
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Ghrelin (Rat) |
| CAS NO. | 258338-12-4 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C147H245N45O42 |
| Molecular Weight | 3314.8g/mol |
| Amino Acid Sequence | Gly-Ser-Ser(n-octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg (28 amino acids) |
| Purity (RP-HPLC) | ≥ 95% (can be customized to ≥ 98%) |
| Solubility | Soluble in water, dilute acetic acid, and PBS |
| Endotoxin | < 1.0 EU/mg |
| Biological Activity | Endogenous peptide hormone that acts as a growth hormone secretagogue and stimulates appetite via activation of the ghrelin receptor (GHSR-1a) in rats. |
| Storage Conditions | Store at –20°C, protected from light and moisture. Long-term storage recommended at –80°C. |
| Stock Location | Stock in USA |
| MOQ | 1mg |
1.MECHANISM OF ACTION
Ghrelin (Rat) acts as an endogenous ligand for the growth hormone secretagogue receptor (GHSR-1a), stimulating the release of growth hormone from the pituitary gland. It also influences appetite and energy homeostasis by activating neurons in the hypothalamus, thereby promoting food intake and modulating metabolic pathways.
2.PRODUCT INDICATIONS
This peptide is used in research focused on growth hormone regulation, obesity, metabolic disorders, and neuroendocrine signaling. It is also applied in studies investigating appetite control, cachexia, and the development of therapeutic strategies for conditions related to growth and metabolism.
3.CLINICAL EFFICACY OF PRODUCT
Preclinical studies demonstrate that Ghrelin (Rat) effectively stimulates growth hormone secretion, increases food intake, and promotes weight gain in animal models. Its potential therapeutic applications in treating cachexia, growth disorders, and metabolic syndromes are supported by experimental data, though clinical translation is still under investigation.
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