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[Tyr0] Gastric Inhibitory Peptide (23-42), human

[Tyr0] Gastric Inhibitory Peptide (23-42), human is a synthetic peptide fragment derived from the C-terminal region of human Gastric Inhibitory Polypeptide (GIP), featuring an N-terminal tyrosine modification. This 20-amino acid peptide (including the added Tyr residue) is designed for enhanced detection and analytical applications in metabolic research. The tyrosine addition facilitates radiolabeling, improves solubility, and enables efficient conjugation for immunoassays. Supplied as a high-purity lyophilized powder with HPLC-verified quality, this peptide serves as a valuable tool for antibody development, receptor binding studies, and diagnostic assay development related to incretin hormone research.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	[Tyr0] Gastric Inhibitory Peptide (23-42), human
CAS NO.	/
Appearance	White to off-white lyophilized powder
Molecular Formula	C119H182N34O31
Molecular Weight	2584.9g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in water, dilute acetic acid, DMSO
Endotoxin	< 1.0 EU/mg
Biological Activity	A Tyr-modified derivative of the C-terminal fragment (positions 23-42) of human gastric inhibitory peptide (GIP); this fragment may be involved in GIP receptor binding and signal regulation, and is commonly used in receptor structure-function studies, antibody development, or as a detection standard.
Storage Conditions	Store at -20°C or below, protected from light and moisture. After reconstitution, aliquot and store at -20°C
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

[Tyr0] GIP (23-42), human represents the C-terminal fragment of the full-length GIP hormone, which may contain receptor interaction domains or antibody recognition epitopes. The N-terminal tyrosine modification does not significantly alter the peptide's biological properties but provides a functional handle for conjugation, labeling, or detection purposes. This peptide can be used to study the role of specific GIP domains in receptor binding, to generate antibodies targeting the C-terminal region, or as a standard in immunoassays. It may exhibit partial receptor binding activity depending on the specific fragment and experimental conditions, but its primary utility lies in analytical and detection applications rather than full biological agonism.

2.PRODUCT INDICATIONS

Antibody Production: Serve as an immunogen to generate polyclonal or monoclonal antibodies targeting the C-terminal region of GIP

Receptor Binding Studies: Investigate the role of specific GIP domains in receptor interaction and signal transduction

Diagnostic Research: Develop diagnostic tools for measuring GIP levels in metabolic disorders

Conjugation Applications: Utilize the tyrosine residue for radiolabeling (e.g., with iodine-125) or chemical conjugation to carriers

Structural Studies: Analyze peptide-receptor interactions and epitope mapping

Immunoassay Development: Use as a coating antigen, standard, or tracer in ELISA, RIA, or other immunoassays for GIP detection

3.CLINICAL EFFICACY OF PRODUCT

High Purity: ≥95% by RP-HPLC with mass spectrometry confirmation of sequence and modification

Enhanced Detectability: N-terminal tyrosine facilitates efficient radiolabeling and conjugation for sensitive detection methods

Batch Consistency: Reproducible synthesis and purification ensure reliable performance across experiments

Analytical Utility: Validated for use in immunoassays, antibody development, and receptor binding studies

Quality Documentation: Each batch includes Certificate of Analysis with purity, mass spec, and amino acid analysis data

Research Flexibility: Suitable for both in vitro binding studies and diagnostic assay development

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.