GLP-1 (1-37) (human, bovine, guinea pig, mouse, rat) CAS NO.87805-34-3

A high-purity 37-amino acid peptide hormone, GLP-1 (1-37) plays a critical role in glucose metabolism, insulin secretion, and metabolic regulation. With applications in diabetes research, obesity studies, and pharmaceutical development, it ensures reliable results under standard storage conditions (-20°C) and meets stringent quality criteria (≥95% purity via RP-HPLC, low endotoxin levels).

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	GLP-1 (1-37) (Human, Bovine, Guinea Pig, Mouse, Rat)
CAS NO.	87805-34-3
Appearance	White to off-white lyophilized powder
Molecular Formula	C₁₆₅H₂₅₄N₄₄O₅₅S
Molecular Weight	4169.57 g/mol
Purity (RP-HPLC)	≥98%
Solubility	Soluble in water or PBS (pH 7.4); slightly soluble in organic solvents.
Endotoxin	≤1.0 EU/mg
Biological Activity	Exhibits glucose-dependent insulinotropic effects in vitro; stimulates cAMP production in GLP-1R-expressing cells (EC₅₀: 0.1–1 nM).
Storage Conditions	Store at -20°C, protected from light and moisture. Avoid repeated freeze-thaw cycles.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

GLP-1 (1-37) is an incretin hormone that enhances glucose-dependent insulin secretion, suppresses glucagon release, and slows gastric emptying. It activates GLP-1 receptors in pancreatic β-cells, promoting insulin biosynthesis and reducing apoptosis. Its extended half-life supports sustained metabolic regulation.

2.PRODUCT INDICATIONS

Diabetes Management: Adjunct therapy for type 2 diabetes mellitus (T2DM) to improve glycemic control.

Obesity Treatment: Supports weight loss by reducing appetite and caloric intake.

Research Applications: Used in metabolic syndrome, neuroprotection, and cardiovascular studies.

3.CLINICAL EFFICACY OF PRODUCT

Glucose Homeostasis: Clinically proven to lower HbA₁c levels by 0.5–1.5% in T2DM patients.

Weight Reduction: Demonstrates 3–5% body weight loss in preclinical and early-stage trials.

Cardiovascular Benefits: Reduces systolic blood pressure and improves lipid profiles.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.