english

gp100 (619-627)

Introducing gp100 (619–627), a premium synthetic peptide engineered for cutting-edge oncology and immunotherapy research. With a precise molecular formula of C₄₉H₈₂N₁₄O₁₄S and a molecular weight of 1123.35, this high-purity antigenic sequence (619–627) targets melanoma cells via MHC class I pathways, enabling robust activation of cytotoxic T lymphocytes (in vitro). Ideal for developing personalized cancer therapies, it delivers consistent results in cell-based assays, vaccine design, and functional validation studies. Backed by rigorous quality control and supported by ISO-certified manufacturing, this peptide empowers researchers to explore antigen-specific immune responses with confidence.

Send Email

Download

TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	GLP - 2 (1 - 33) (human)
CAS NO.	223460 - 79 - 5
Appearance	White to off-white lyophilized powder
Molecular Formula	C₁₆₅H₂₅₄N₄₄O₅₅S
Molecular Weight	5040.74g/mol
Purity (RP-HPLC)	≥98%
Solubility	Soluble in water or phosphate - buffered
Endotoxin	≤1.0 EU/mg
Biological Activity	GLP - 2 (1 - 33) (human) has significant biological activity. It is known to play a key role in promoting intestinal growth, enhancing intestinal epithelial cell proliferation, and increasing intestinal absorption capacity. In addition, it can modulate the immune response within the gut, protecting the intestinal mucosa from damage and inflammation.
Storage Conditions	To maintain the stability and integrity of GLP - 2 (1 - 33) (human), it should be stored at - 20°C or below in a dry environment.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

Stimulates cytotoxic T lymphocytes (CTLs) via major histocompatibility complex (MHC) class I presentation.

Enhances antigen-specific immune responses against melanoma cells expressing gp100.

Facilitates precise targeting of tumor-associated antigens for immunotherapy applications.

2.PRODUCT INDICATIONS

Research Use Only: Intended for preclinical studies on melanoma immunotherapy.

Cell-Based Assays: Suitable for evaluating T-cell activation and antitumor activity in vitro.

Therapeutic Development: Supports the design of gp100-based vaccines or adoptive cell therapies.

3.CLINICAL EFFICACY OF PRODUCT

Preclinical Studies: Demonstrated potent CTL proliferation and cytokine release in melanoma models.

Functional Validation: Proven efficacy in enhancing tumor cell lysis viaMHC-restricted pathways.

Research Applications: Enables validation of gp100-targeted immunotherapies in benchtop experiments.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.